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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:

33卷

期数:

2020年15期

页码:

167-169

栏目:

诊疗技术

出版日期:

2020-08-01

文章信息/Info

Title:

Diagnostic Value of Blue Laser Magnifying Gastroscope for Gastric MucosalAtrophy and Intestinal Metaplasia

文章编号:

1006-1959（2020）15-0167-03

作者:

赖 辉1; 余 焰1; 钟福杭2

上杭县医院消化内科1，病理科2，福建 龙岩 364200

Author(s):

LAI Hui1; YU Yan1; ZHONG Fu-hang2

Department of Gastroenterology1,Department of Pathology2,Shanghang County Hospital,Longyan 364200,Fujian,China

关键词:

蓝激光放大胃镜; 胃粘膜萎缩; 肠上皮化生

Keywords:

Blue laser magnifying gastroscope; Gastric mucosal atrophy; Intestinal metaplasia

分类号:

R573

DOI:

10.3969/j.issn.1006-1959.2020.15.053

文献标志码:

A

摘要:

目的 探讨蓝激光放大胃镜对胃粘膜萎缩及肠上皮化生的诊断效果。方法 选取2019年5月~2020年4月我院门诊及住院收治的上消化道症状患者113例作为研究对象，所有患者行无痛蓝激光胃镜检查。根据不同观察模式下胃粘膜肠上皮化生特异性表现进行分组：联动成像（LCI）模式下见淡紫色调，蓝激光放大胃镜（BLI-ME）下未见亮蓝嵴的患者纳入α组；LCI模式下未见淡紫色调、BLI-ME模式下存在亮蓝嵴的患者纳入β组；LCI模式下见淡紫色调且BLI-ME模式存在亮蓝嵴的患者纳入γ组。比较三组HP、活动性、炎性、萎缩及肠化生发生情况；结合病理诊断结果与内镜诊断结果，比较三组肠化生诊断的灵敏度、特异性、准确性。结果 三组HP、活动性、炎性及萎缩患者比较，差异无统计学意义（P＞0.05）；三组患者肠化生例数比较，差异有统计学意义（P＜0.05）；γ组胃粘膜肠上皮化生诊断的敏感性、特异性及准确性均高于α、β组，α组的敏感性、特异性及准确性略高于β，差异有统计学意义（P＜0.05）。对蓝激光胃镜下胃黏膜萎缩的白光、LCI、BLI-bri及BLI-ME镜下及病理表现予以观察，LCI及BLI观察模式下胃黏膜萎缩表现较白光下敏感性、特异性及准确性均较高。结论 蓝激光放大胃镜对于胃粘膜萎缩及肠上皮化生具有较高的诊断价值，LCI及BLI观察模式下胃黏膜萎缩表现较白光下敏感性、特异性及准确性均较高。

Abstract:

Objective To investigate the diagnostic effect of blue laser magnifying gastroscope on gastric mucosal atrophy and intestinal metaplasia. Methods 113 patients with upper gastrointestinal symptoms admitted to our hospital from May 2019 to April 2020 were selected as the research objects. All patients underwent painless blue laser gastroscopy. Groups were grouped according to the specific manifestations of gastric mucosal intestinal metaplasia under different observation modes: patients with lavender hue under Linked Imaging (LCI) mode and no bright blue ridge under blue laser magnifying gastroscope (BLI-ME) were included in the α group; Patients with no lavender tone in LCI mode and bright blue ridge in BLI-ME mode were included in the β group; patients with lavender tone in LCI mode and bright blue ridge in BLI-ME mode were included in the γ group. Compare the occurrence of HP, activity, inflammation, atrophy and intestinal metaplasia in the three groups; combine the results of pathological diagnosis and endoscopic diagnosis to compare the sensitivity, specificity and accuracy of the diagnosis of intestinal metaplasia in the three groups. Results There was no statistically significant difference among the three groups of patients with HP, activity, inflammation and atrophy (P>0.05); the three groups of patients with intestinal metaplasia compared with the number of cases, the difference was statistically significant (P<0.05); the stomach of the γ group the sensitivity, specificity and accuracy of the diagnosis of mucosal intestinal metaplasia were higher than those of the α and β groups. The sensitivity, specificity and accuracy of the α group were slightly higher than that of β,the difference was statistically significant (P<0.05). The white light, LCI, BLI-bri and BLI-ME microscopic and pathological manifestations of gastric mucosal atrophy under blue laser gastroscopy were observed. The sensitivity, specificity and accuracy of gastric mucosal atrophy under LCI and BLI observation modes are higher than those under white light.Conclusion Blue laser magnifying gastroscopy has high diagnostic value for gastric mucosal atrophy and intestinal metaplasia. The performance of gastric mucosal atrophy under LCI and BLI observation modes is more sensitive, specific and accurate than white light.

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更新日期/Last Update: 1900-01-01