[1]陈海丹,张 华,曾繁娟,等.2005年~2015年三亚地区出生低体重儿罹患慢性肾脏病危险因素的横断面研究[J].医学信息,2021,34(03):151-153.[doi:10.3969/j.issn.1006-1959.2021.03.042]
　CHEN Hai-dan,ZHANG Hua,ZENG Fan-juan,et al.A Cross-sectional Study on the Risk Factors of Chronic Kidney Disease in Low Birth Weight Infants in Sanya from 2005 to 2015[J].Medical Information,2021,34(03):151-153.[doi:10.3969/j.issn.1006-1959.2021.03.042]
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2005年~2015年三亚地区出生低体重儿罹患慢性肾脏病危险因素的横断面研究()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
34卷
期数:
2021年03期
页码:
151-153
栏目:
调查分析
出版日期:
2021-02-01

文章信息/Info

Title:
A Cross-sectional Study on the Risk Factors of Chronic Kidney Disease in Low Birth Weight Infants in Sanya from 2005 to 2015
文章编号:
1006-1959（2021）03-0151-03
作者:
陈海丹; 张 华; 曾繁娟; 等
（三亚中心医院/海南省第三人民医院儿科，海南 三亚 572000）
Author(s):
CHEN Hai-dan; ZHANG Hua; ZENG Fan-juan; et al.
(Department of Pediatrics,Sanya Central Hospital/the Third People’s Hospital of Hainan Province,Sanya 572000,Hainan,China)
关键词:
三亚地区; 慢性肾病; 低出生体重儿
Keywords:
Sanya area; Chronic kidney disease; Low birth weight infants
分类号:
R692
DOI:
10.3969/j.issn.1006-1959.2021.03.042
文献标志码:
A
摘要:
目的 调查三亚地区2005年~2015年出生低体重儿罹患慢性肾脏疾病（CKD）的检出率，分析其危险因素。方法 收集2005~2015年海南省三亚地区3个重点医院的出生低体重儿，对所有可追溯的儿童进行为期24个月随访，观察CKD的筛出率，采用Logistic回归分析出生低体重儿发生CKD的危险因素。结果 最终纳入1219例低出生体重儿，共确诊CKD患儿33例，检出率为2.71%，其中CKDⅠ期20例，CKDⅡ期13例；单因素分析显示，不同孕周、出生体重、血肌酐、Ccr、舒张压、血尿素氮、血清白蛋白、尿白蛋白、空腹血糖、运动行为指数的出生低体重儿CKD的检出率比较，差异有统计学意义（P＜0.05）；二元Logistic回归分析显示，孕周、Ccr、血清白蛋白和运动行为指数是早产儿及出生低体重儿罹患CKD的保护因素，血肌酐、舒张压、尿白蛋白、空腹血糖是早产儿及出生低体重儿罹患CKD的危险因素。结论 血肌酐、舒张压、尿白蛋白、空腹血糖是低出生体重儿发生CKD的危险因素，而高运动指数、高血清白蛋白、高孕周有利于降低低出生体重儿CKD的发生。
Abstract:
Objective To investigate the detection rate of chronic kidney disease (CKD) in low birth weight infants in Sanya from 2005 to 2015, and analyze its risk factors.Methods A collection of low birth weight infants from three key hospitals in Sanya, Hainan Province from 2005 to 2015 was conducted. All traceable children were followed up for 24 months to observe the screening rate of CKD.Logistic regression was used to analyze the risk factors of CKD in low birth weight infants.Results Finally, 1219 low birth weight infants were included. A total of 33 children with CKD were diagnosed with a detection rate of 2.71%, including 20 cases of CKD stage I and 13 cases of CKD stage II;Univariate analysis showed that the detection rate of CKD in low birth weight infants with different gestational weeks, birth weight, blood creatinine, Ccr, diastolic blood pressure, blood urea nitrogen, serum albumin, urine albumin, fasting blood glucose, and exercise behavior index were compared,the difference was statistically significant (P＜0.05);Binary Logistic regression analysis showed that gestational age, Ccr, serum albumin and exercise behavior index are the protective factors for premature infants and low birth weight infants from CKD. Serum creatinine, diastolic blood pressure, urine albumin, and fasting blood glucose were preterm infants and births. Risk factors for CKD in low birth weight infants.Conclusion Serum creatinine, diastolic blood pressure, urine albumin, and fasting blood glucose are risk factors for CKD in low birth weight infants. High exercise index, high serum albumin, and high gestational age are beneficial to reduce the occurrence of CKD in low birth weight infants.

参考文献/References:

[1]王颖颖,曹云.新生儿急性肾损伤诊断及生物标记物研究进展[J].中华围产医学杂志,2018,21(9):626-631. [2]谢剑露,刘绍基.新生儿急性肾损伤与慢性肾脏病[J].国际儿科学杂志,2015(4):405-408. [3]Das SK,Mannan M,Faruque ASG,et al.Effect of birth weight on adulthood renal function:A bias-adjusted meta-analytic approach[J].Nephrology,2016(2016):547-565. [4]Abitbol CL,Moxey-Mims M.Chronic kidney disease:Low birth weight and the global burden of kidney disease[J].Nature Reviews Nephrology,2016,12(4):199-200. [5]邵肖梅,叶鸿帽,丘小汕.实用新生儿学[M].第4版.北京:人民卫生出版社,2011. [6]王学晶.儿童肾小球滤过率的评估方法[J].中华儿科杂志,2016,54(7):539-542. [7]Jabbari B,Vaziri ND.The nature,consequences,and management of neurological disorders in chronic kidney disease[J].Hemodialysis International,2018,22(2):150-160. [8]Zhao YY.Applications of LC-based metabolomics in chronic kidney diseases[J].Chinese Journal of Pharmacology and Toxicology,2013,27(5):769-775. [9]Langley-Evans SC.Critical differences between two low protein diet protocols in the programming of hypertension in the rat[J].Int J Food Sci Nutr,2000,51(1):11-17. [10]Brennan S,Kandasamy Y.Renal parenchymal thickness as a measure of renal growth in low-birth-weight infants versus normal-birth-weight infants[J].Ultrasound in Medicine&Biology,2013,39(12):2315-2320. [11]张若林,帅兰军,李晓燕,等.出生体重与慢性肾脏病关联性的系统评价和Meta分析[J].中国循证儿科杂志,2017,12(2):93-99. [12]Girndt M.Diagnosis and treatment of chronic kidney disease[J].Internist(Berl),2017,58(3):243-256. [13]赵璐,梅长林,邬碧波,等.上海市静安区慢性肾脏病高危人群社区筛查结果分析[J].中华肾脏病杂志,2020,36(1):1-5. [14]冯晋,张爱华.慢性肾脏病合并高血压的新机制[J].中华肾病研究电子杂志,2020,9(1):33-37. [15]刘旭利,程庆砾,高军,等.北京城区军队高龄男性代谢综合征与慢性肾脏病的相关性研究[J].中华保健医学杂志,2020,22(2):169-172. [16]张晓蕾,贾鸿雁.早期慢性肾脏病患者社区-家庭-自我管理近远期效果分析[J].中国全科医学,2020,23(11):1361-1367. [17]北京大学医学系糖尿病肾脏病专家共识协作组.糖尿病肾脏病诊治专家共识[J].中华医学杂志,2020,100(4):247-260.

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更新日期/Last Update: 1900-01-01