[1]段 帮,吴华东.灯盏花素联合盐酸倍他司汀治疗眩晕症的疗效[J].医学信息,2021,34(23):87-89.[doi:10.3969/j.issn.1006-1959.2021.23.024]
　DUAN Bang,WU Hua-dong.Therapeutic Effect of Breviscapine Combined with Betahistine Hydrochloride on Vertigo[J].Medical Information,2021,34(23):87-89.[doi:10.3969/j.issn.1006-1959.2021.23.024]
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灯盏花素联合盐酸倍他司汀治疗眩晕症的疗效()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
34卷
期数:
2021年23期
页码:
87-89
栏目:
论著
出版日期:
2021-12-01

文章信息/Info

Title:
Therapeutic Effect of Breviscapine Combined with Betahistine Hydrochloride on Vertigo
文章编号:
1006-1959（2021）23-0087-03
作者:
段 帮; 吴华东
（贵溪市人民医院神经内科，江西 贵溪 335400）
Author(s):
DUAN Bang; WU Hua-dong
(Department of Neurology,Guixi People’s Hospital,Guixi 335400,Jiangxi,China)
关键词:
盐酸倍他司汀; 眩晕症; 血浆黏度
Keywords:
Betahistine hydrochloride; Vertigo; Plasma viscosity
分类号:
R441.2
DOI:
10.3969/j.issn.1006-1959.2021.23.024
文献标志码:
A
摘要:
目的 观察灯盏花素联合盐酸倍他司汀治疗眩晕症的临床疗效。方法 选取2019年1月-2021年6月我院诊治的52例眩晕症患者为研究对象，采用随机数字表法分为对照组和观察组，各26例。对照组予以注射用灯盏花素治疗，观察组在对照组基础上联合盐酸倍他司汀注射液治疗，比较两组治疗疗效、眩晕症症状消失时间、眩晕障碍评分、临床症状评分、血液流变学指标(血浆黏度、红细胞聚集指数）及不良反应发生情况。结果 观察组治疗总有效率为92.30%，高于对照组的80.76%，差异有统计学意义（P＜0.05）；观察组眩晕症症状消失时间短于对照组，眩晕障碍评分低于对照组，差异有统计学意义（P＜0.05）；观察组眩晕、头痛、恶心呕吐评分低于对照组，差异有统计学意义（P＜0.05）；观察组血浆黏度、红细胞聚集指数低于对照组，差异有统计学意义（P＜0.05）；两组不良反应总发生率比较，差异无统计学意义（P＞0.05）。结论 灯盏花素联合盐酸倍他司汀治疗眩晕症效果确切，可缩短症状消失时间，改善临床症状及血液流变学指标，且联合用药不增加不良反应发生几率。
Abstract:
Objective To observe the clinical effect of breviscapine combined with betahistine hydrochloride in the treatment of vertigo.Methods A total of 52 patients with vertigo who were treated in our hospital from January 2019 to June 2021 were selected as the research objects. They were divided into control group and observation group by random number table method, 26 cases in each group. The control group was treated with breviscapine for injection, and the observation group was treated with betahistine hydrochloride injection on the basis of the control group. The therapeutic effect, disappearance time of vertigo symptoms, vertigo disorder score, clinical symptom score, hemorheology indexes (plasma viscosity, erythrocyte aggregation index) and adverse reactions were compared between the two groups.Results The total effective rate of the observation group was 92.30%, which was higher than 80.76% of the control group, and the difference was statistically significant (P<0.05). The disappearance time of vertigo symptoms in the observation group was shorter than that in the control group, and the vertigo disorder score was lower than that in the control group, the difference was statistically significant (P<0.05). The scores of vertigo, headache, nausea or vomiting in the observation group were lower than those in the control group, and the difference was statistically significant (P<0.05). The plasma viscosity and erythrocyte aggregation index in the observation group were lower than those in the control group, and the difference was statistically significant (P<0.05). There was no significant difference in the total incidence of adverse reactions between the two groups (P>0.05).Conclusion Breviscapine combined with betahistine hydrochloride is effective in the treatment of vertigo, which can shorten the disappearance time of symptoms, improve clinical symptoms and hemorheology indexes, and the combination does not increase the incidence of adverse reactions.

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更新日期/Last Update: 1900-01-01