[1]吕 冰,田利成,何振芬.限制性液体复苏与常规液体复苏治疗创伤性休克的疗效比较[J].医学信息,2021,34(23):114-116.[doi:10.3969/j.issn.1006-1959.2021.23.033]
 LYU Bing,TIAN Li-cheng,HE Zhen-fen.Comparison of Limited Fluid Resuscitation and Conventional Fluid Resuscitation in the Treatment of Traumatic Shock[J].Medical Information,2021,34(23):114-116.[doi:10.3969/j.issn.1006-1959.2021.23.033]
点击复制

限制性液体复苏与常规液体复苏治疗创伤性休克的疗效比较()
分享到:

医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
34卷
期数:
2021年23期
页码:
114-116
栏目:
论著
出版日期:
2021-12-01

文章信息/Info

Title:
Comparison of Limited Fluid Resuscitation and Conventional Fluid Resuscitation in the Treatment of Traumatic Shock
文章编号:
1006-1959(2021)23-0114-03
作者:
吕 冰田利成何振芬
(天津市宝坻区人民医院急诊科,天津 301800)
Author(s):
LYU BingTIAN Li-chengHE Zhen-fen
(Department of Emergency,Tianjin Baodi District People’s Hospital,Tianjin 301800,China)
关键词:
限制性液体复苏常规液体复苏创伤性休克
Keywords:
Limited fluid resuscitationConventional liquid recoveryTraumatic shock
分类号:
R641
DOI:
10.3969/j.issn.1006-1959.2021.23.033
文献标志码:
A
摘要:
目的 比较限制性液体复苏与常规液体复苏治疗创伤性休克的临床疗效。方法 选取2020年1月-2021年1月天津市宝坻区人民医院收治的98例创伤性休克患者作为研究对象,通过随机数字表法分为观察组和对照组,各49例。对照组采用常规液体复苏治疗,观察组采用限制性液体复苏治疗,比较两组血气指标[动脉血氧分压(PaO2)、动脉血二氧化碳分压(PaCO2)、血pH值、剩余碱(BE)以及血乳酸(BL)]、凝血功能指标[活化部分凝血活酶时间(APTT)、凝血酶时间(TT)、凝血酶原时间(PT)]、液体复苏时间、液体使用量及并发症发生情况。结果 两组治疗后PaO2、PaCO2、血pH值、BE、BL优于治疗前,且观察组优于对照组,差异有统计学意义(P<0.05);两组治疗后APTT、TT、PT高于治疗前,且观察组高于对照组,差异有统计学意义(P<0.05);观察组液体复苏时间低于对照组,液体使用量少于对照组,差异有统计学意义(P<0.05);观察组并发症总发生率为10.20%,低于对照组的30.61%,差异有统计学意义(P<0.05)。结论 限制性液体复苏治疗有利于改善创伤性休克患者氧代谢及凝血功能,预后良好,且并发症发生率低。
Abstract:
Objective To compare the clinical efficacy of limited fluid resuscitation and conventional fluid resuscitation in the treatment of traumatic shock.Methods A total of 98 patients with traumatic shock admitted to Tianjin Baodi District People ’ s Hospital from January 2020 to January 2021 were selected and divided into observation group and control group by random number table method, with 49 cases in each group. The control group was treated with conventional fluid resuscitation, and the observation group was treated with restrictive fluid resuscitation. The blood gas indexes [arterial oxygen partial pressure (PaO2), arterial carbon dioxide partial pressure (PaCO2), blood pH value, residual base (BE) and blood lactic acid (BL)], coagulation function indexes [activated partial thromboplastin time (APTT), thrombin time (TT), prothrombin time (PT)], fluid resuscitation time, fluid usage and complications were compared between the two groups.Results PaO2, PaCO2, blood pH, BE and BL in the two groups after treatment were better than those before treatment, and those in the observation group were better than the control group, the difference was statistically significant (P<0.05). APTT, TT and PT of the two groups after treatment were higher than those before treatment, and the observation group was higher than the control group, the difference was statistically significant (P<0.05). The fluid resuscitation time of the observation group was lower than that of the control group, and the liquid usage was less than that of the control group, the difference was statistically significant (P<0.05). The total incidence of complications in the observation group was 10.20%, which was lower than 30.61% in the control group, and the difference was statistically significant (P<0.05).Conclusion Limited fluid resuscitation is beneficial to improve oxygen metabolism and coagulation function in patients with traumatic shock, with good prognosis and low incidence of complications.

参考文献/References:

[1]张超,苏建文.PICCO技术指导限制性液体复苏在严重创伤失血性休克抢救中的应用[J].海南医学,2021,32(1):42-45. [2]Lou X,Lu G,Zhao M,et al.Preoperative fluid management in traumatic shock: A retrospective study for identifying optimal therapy of fluid resuscitation for aged patients[J].Medicine,2018,97(8):e9966.[3]赵磊,刘卓,李卫.高渗盐水输注联合限制性液体复苏、血量补充在重症胸部创伤后失血性休克患者急诊救治中的应用效果[J].临床医学研究与实践,2021,6(4):73-75. [4]惠晓艳,王小平.液体复苏策略治疗创伤性休克伴创伤性凝血功能障碍[J].血栓与止血学,2021,27(1):71-74.[5]Hwabejire JO,Nembhard CE,Oyetunji TA,et al.Abdominal compartment syndrome in traumatic hemorrhagic shock: is there a fluid resuscitation inflection point associated with increased risk?[J].Am J Surg,2016, 211(4):733-738.[6]陈东方,陈庆永,陈阳龙,等.限制性液体复苏联合体温管理在腹部严重创伤伴失血性休克患者中的应用效果[J].中华灾害救援医学,2020,8(1):52-54. [7]Wang H,Chen MB,Zheng XW,et al.Effectiveness and safety of hypotensive resuscitation in traumatic hemorrhagic shock: A protocol for meta-analysis[J].Medicine (Baltimore),2019,98(48):e18145.[8]吴春艳.限制性液体复苏应用于创伤失血性休克急救中对凝血功能的影响[J].血栓与止血学,2020,26(2):305-306.[9]严晓薇,李小东,李素清,等.限制性液体复苏在休克伴TIC患者中应用的临床研究[J].临床合理用药杂志,2018,11(11):8-9,11.[10]曹粒,眭建,叶向红.限制性液体复苏结合多模式疼痛管理对下肢骨折伴创伤失血性休克患者的影响[J].临床与病理杂志,2020,40(7):1763-1770.[11]Hjortrup PB,Haase N,Bundgaard H,et al.Restricting volumes of resuscitation fluid in adults with septic shock after initial management: the CLASSIC randomised, parallel-group, multicentre feasibility trial[J].Intensive Care Med,2016,42(11):1695-1705.[12]韩力,赵建文,王晓伟,等.限制性液体复苏对多发性骨折合并创伤失血性休克患者凝血功能、心肌损害指标及预后的影响[J].现代生物医学进展,2020,20(11):2068-2071. [13]范凤珍,黄有环,王安霞,等.冷沉淀凝血因子配合限制性液体复苏在创伤性失血性休克救治中的应用研究[J].临床急诊杂志,2020,21(7):563-567. [14]Chang R,Holcomb JB.Optimal Fluid Therapy for Traumatic Hemorrhagic Shock[J].Crit Care Clin,2017,33(1):15-36.[15]van Haren F.Personalised fluid resuscitation in the ICU: still a fluid concept[J].Crit Care,2017,21(Suppl 3):313.

更新日期/Last Update: 1900-01-01