[1]盛海龙,方长太,查佳安.超声造影对重症急性胰腺炎并发早期急性肾损的诊断价值[J].医学信息,2022,35(09):171-174.[doi:10.3969/j.issn.1006-1959.2022.09.044]
　SHENG Hai-long,FANG Chang-tai,ZHA Jia-an.Diagnostic Value of Contrast-enhanced Ultrasonography in Severe Acute Pancreatitis Complicated with Early Acute Kidney Injury[J].Medical Information,2022,35(09):171-174.[doi:10.3969/j.issn.1006-1959.2022.09.044]
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超声造影对重症急性胰腺炎并发早期急性肾损的诊断价值()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
35卷
期数:
2022年09期
页码:
171-174
栏目:
诊疗技术
出版日期:
2022-05-01

文章信息/Info

Title:
Diagnostic Value of Contrast-enhanced Ultrasonography in Severe Acute Pancreatitis Complicated with Early Acute Kidney Injury
文章编号:
1006-1959（2022）09-0171-04
作者:
盛海龙; 方长太; 查佳安
（安徽医科大学附属安庆市立医院急诊科1，重症医学科2，安徽 安庆 246000）
Author(s):
SHENG Hai-long; FANG Chang-tai; ZHA Jia-an
(Department of Emergency1,Department of Critical Medicine2,Anqing Municipal Hospital Affiliated to Anhui Medical University,Anqing 246000,Anhui,China)
关键词:
超声造影; 重症急性胰腺炎; 急性肾损伤; 肾皮质; 血流灌注
Keywords:
Contrast-enhanced ultrasonography; Severe acute pancreatitis; Acute kidney injury; Renal cortex; Blood perfusion
分类号:
R692.5
DOI:
10.3969/j.issn.1006-1959.2022.09.044
文献标志码:
A
摘要:
目的 探讨超声造影对重症急性胰腺炎（SAP）并发早期急性肾损的诊断价值。方法 选取2019年12月-2021年6月安庆市立医院重症医学科收治的71例SAP患者作为研究对象，所有患者入院24 h内完成肾脏超声造影、肾功能指标（血肌酐、尿素氮、肌酐清除率）测定，然后根据KDIGO-AKI诊断标准将患者分成肾功能损伤（A1）组27例及非肾功能损伤（N1）组44例，比较两组超声造影参数（PI、TTP、AUC），连续7天监测患者肾功能，第7天再次根据AKI诊断标准将N1组患者分为肾功能损伤（A2）组15例及非肾功能损伤（N2）组29例，比较两组入院24 h内留取的肾脏造影参数与肾功能（血肌酐、尿素氮、肌酐清除率）指标。结果 A1组PI、AUC小于N1组，TTP大于N1组，差异有统计学意义（P＜0.05）；A2与N2组PI、TTP、AUC比较，差异均有统计学意义（P＜0.05）；两组血肌酐、尿素氮、肌酐清除率比较，差异无统计学意义（P＞0.05）。结论 肾脏超声造影在SAP性AKI的诊断中具有重要的预测价值；尤其在AKI早期，其造影参数变化早于实验室指标，通过造影参数定量分析急性肾损伤时肾实质血流灌注情况，在SAP并发AKI早期即可进行诊断。
Abstract:
Objective To investigate the diagnostic value of contrast-enhanced ultrasonography in severe acute pancreatitis complicated with early acute kidney injury.Methods Seventy-one patients with SAP admitted to the Department of Critical Care Medicine of Anqing Municipal Hospital from December 2019 to June 2021 were selected as subjects. All patients underwent renal contrast-enhanced ultrasound and renal function indexes (serum creatinine, urea nitrogen and creatinine clearance rate) were measured within 24 hours of admission. According to KDIGO-AKI diagnostic criteria, the patients were divided into renal function injury (A1) group (n=27) and non-renal function injury (N1) group (n=44). The contrast-enhanced ultrasound parameters (PI, TTP, AUC) were compared between the two groups, and the renal function of the patients was monitored for 7 days. On the 7th day, patients in the N1 group were again divided into renal function injury (A2) group (15 cases) and non-renal function injury (N2) group (29 cases) according to the AKI diagnostic criteria, and the renal angiography parameters and renal function (serum creatinine, urea nitrogen, creatinine clearance rate) indexes were compared between the two groups within 24 h after admission.Results PI and AUC of group A1 were lower than those of group N1, and TTP was higher than that of group N1, the difference was statistically significant(P<0.05). PI and AUC of group A1 were lower than those of group N1, and TTP was higher than that of group N1, the difference was statistically significant (P<0.05). There was no significant difference in serum creatinine, urea nitrogen and creatinine clearance rate between the two groups (P>0.05).Conclusion Renal contrast-enhanced ultrasonography has important predictive value in the diagnosis of SAP AKI. Especially in the early stage of AKI, the changes of contrast parameters are earlier than the laboratory indexes. Quantitative analysis of renal parenchymal blood perfusion in acute renal injury by contrast parameters can be used for early diagnosis of SAP complicated with AKI.

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更新日期/Last Update: 1900-01-01