[1]赵 超.能谱CT成像鉴别实性肺癌病理类型的定量参数及诊断作用分析[J].医学信息,2022,35(16):98-101.[doi:10.3969/j.issn.1006-1959.2022.16.023]
 ZHAO Chao.Quantitative Parameters and Diagnostic Value of Energy Spectrum CT Imaging in Differentiating Pathological Types of Solid Lung Cancer[J].Journal of Medical Information,2022,35(16):98-101.[doi:10.3969/j.issn.1006-1959.2022.16.023]
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能谱CT成像鉴别实性肺癌病理类型的定量参数及诊断作用分析()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
35卷
期数:
2022年16期
页码:
98-101
栏目:
论著
出版日期:
2022-08-15

文章信息/Info

Title:
Quantitative Parameters and Diagnostic Value of Energy Spectrum CT Imaging in Differentiating Pathological Types of Solid Lung Cancer
文章编号:
1006-1959(2022)16-0098-04
作者:
赵 超
(天津市静海区医院CT室,天津 301600)
Author(s):
ZHAO Chao
(CT Room,Jinghai Hospital,Tianjin 301600,China)
关键词:
实性肺癌能谱CT成像病理类型定量参数
Keywords:
Solid lung cancerEnergy spectrum CT imagingPathological typeQuantitative parameters
分类号:
R734.2;R445.3
DOI:
10.3969/j.issn.1006-1959.2022.16.023
文献标志码:
A
摘要:
目的 分析能谱CT成像鉴别实性肺癌病理类型的定量参数及诊断作用。方法 选取2019年10月-2021年10月经天津市静海区医院确诊的78例实性肺癌病例,给予能谱CT成像检查,对其定量参数及诊断作用进行分析。结果 平扫能谱CT定量参数Eff-Z(有效原子序数)、钙(水)浓度及能谱曲线斜率(K40-65keV)由大到小依次为腺癌>鳞癌>小细胞肺癌(P<0.05);动脉期能谱CT定量参数标准化碘浓度(NIC)及K40-65keV由大到小依次为腺癌>鳞癌>小细胞肺癌(P<0.05)。经ROC曲线分析显示,平扫参数[钙(水)浓度、Eff-Z、K40-65keV]与动脉期参数(NIC、K40-65keV)诊断小细胞肺癌与非小细胞肺癌的曲线下面积分别为0.65、0.63、0.68、0.70、0.57,诊断肺腺癌与鳞癌的曲线下面积分别为0.65、0.66、0.64、0.72、0.63。不同病理类型实性肺癌平扫能谱衰减曲线走势分型比较,差异有统计学意义(P<0.05),其中腺癌多表现为Ⅲ型,鳞癌主要为Ⅱ型,小细胞肺癌则集中在Ⅳ型。结论 能谱CT成像定量参数在不同病理类型的实性肺癌中存在差异,对肺腺癌、鳞癌及小细胞肺癌均具有确切的鉴别诊断价值。
Abstract:
Objective To analyze the quantitative parameters and diagnostic effects of energy spectrum CT imaging in identifying the pathological types of solid lung cancer.Methods A total of 78 solid lung cancer cases diagnosed by Tianjin Jinghai Hospital from October 2019 to October 2021 were selected for energy spectrum CT imaging, and their quantitative parameters and diagnostic effects were analyzed.Results The quantitative parameters Eff-Z (effective atomic number), calcium (water) concentration and energy spectrum curve slope (K40-65keV) of plain energy spectrum CT in descending order were adenocarcinoma>squamous cell carcinoma>small cell lung cancer (P<0.05); the normalized iodine concentration (NIC) and K40-65keV of spectral CT quantitative parameters in arterial phase were adenocarcinoma>squamous cell carcinoma>small cell lung cancer (P<0.05). (P<0.05). ROC curve analysis showed that the area under the curve of plain scan parameters [calcium (water) concentration, Eff-Z, K40-65keV] and arterial phase parameters (NIC, K40-65keV) in the diagnosis of small cell lung cancer and non-small cell lung cancer were 0.65, 0.63, 0.68, 0.70, 0.57, respectively; the area under the curve of lung adenocarcinoma and squamous cell carcinoma was 0.65, 0.66, 0.64, 0.72, 0.63, respectively. Different pathological types of solid lung cancer had differences in the trend classification of the flat scan energy spectrum attenuation curve (P<0.05), Among them, adenocarcinoma was mostly type Ⅲ, squamous cell carcinoma was mainly type Ⅱ, and small cell lung cancer was concentrated in type Ⅳ.Conclusion There are significant differences in the quantitative parameters of energy spectrum CT imaging in solid lung cancer of different pathological types, and it has a definite differential diagnosis value for lung adenocarcinoma, squamous cell carcinoma and small cell lung cancer.

参考文献/References:

[1]王炜华,孙希文,袁明远.高端高分辨薄层CT在早期肺腺癌诊断筛查中的应用[J].检验医学与临床,2019,16(7):865-869,873.[2]赵森,杜森,鲍志国,等.宝石能谱CT对肺鳞癌分化程度的评估价值分析[J].中国体视学与图像分析,2021,26(1):92-99.[3]李琳,罗娅红.一站式CT能谱联合灌注成像技术在肺癌病理类型鉴别中的应用研究[J].现代肿瘤医学,2021,29(6):1032-1035.[4]Cohen JG,Reymond E,Jankowski A,et al.Lung adenocarcinomas: correlation of computed tomography and pathology findings[J].Diagnostic & Interventional Imaging,2016,97(10):955-963.[5]梁远凤,李琦,罗天友.能谱CT平扫定量分析鉴别诊断周围型肺癌与结核球[J].中国医学影像技术,2017,33(8):1206-1210.[6]朱巧,任翠,张艳,等.能谱CT成像评价晚期非小细胞肺癌化疗近期疗效的价值[J].放射学实践,2020,35(8):953-959.[7]贾祯,李卫星,盛俊卿.GSI定量参数对NSCLC患者病理分化程度评估价值探讨[J].社区医学杂志,2020,18(12):886-890.[8]张武.宝石能谱 CT 成像在不同组织来源、病理类型肿瘤及其转移淋巴结中的诊断价值[J].临床和实验医学杂志,2016,15(8):813-815.[9]黄家瑶,汤光宇.宝石CT能谱成像技术在非小细胞肺癌患者中的应用价值[J].中国医师杂志,2020,22(3):432-434.[10]陈麦林,孙应实.能谱CT成像瞬时切换技术对于肺结节的临床价值[J].CT理论与应用研究,2019,28(6):701-708.[11]周智越,曹绍东,韩东,等.能谱CT支气管动脉成像在中央型肺癌中的应用价值[J].医学研究杂志,2019,48(8):150-153,99.[12] 吴金棉,陈云辉,黄洲,等.能谱CT成像定量分析在鉴别诊断周围型肺癌和肺炎性肿块中的临床价值[J].深圳中西医结合杂志,2017,27(17):27-28.[13]戴钢,邓克学,韦炜,等.能谱CT平扫定量分析在非小细胞肺癌与炎性肿块中的鉴别价值[J].中国医学计算机成像杂志,2019,25(1):23-26.[14]钱利明.宝石能谱CT成像的临床应用[J].实用医学影像杂志,2015,16(1):82-83.[15]闫凤全.能谱CT在肺癌病理分型中的应用价值分析[J].现代诊断与治疗,2019,30(15):2627-2628.[16]任占丽,贺太平,张喜荣,等.能谱CT多参数成像在鉴别肺癌病理类型中的价值[J].中国中西医结合影像学杂志,2020,18(5):486-489,501.[17]Fehrenbach U,Kahn J,B?觟ning G,et al.Spectral CT and its specific values in thestaging of patients with non-small cell lung cancer: technical possibilities andclinical impact[J].Clin Radiol,2019,74(6):456-466.[18]周航,武峰.肺癌CT能谱成像:定量分析及与TTF-1和EGFR表达水平的相关性[J].放射学实践,2017,32(8):839-842.[19]田彤彤,叶靖,彭铮堃,等.低剂量能谱CT结合ASIR重建对肺部炎性肿块与周围型肺癌的鉴别诊断价值[J].实用医学杂志,2017,33(16):2769-2772.[20]周静宜,刘芸,黄劲柏.宝石能谱CT成像在不同病理类型肺癌分类诊断的价值探讨[J].CT理论与应用研究,2017,26(3):291-298.[21]梁远凤,李琦,马超豪,等.肺癌癌周灌注的能谱CT定量研究[J].重庆医科大学学报,2017,42(3):357-360.[22]陈盈,姚琼瑛,郑昊,等.能谱CT在肺癌淋巴结转移诊断中的临床应用研究[J].肿瘤学杂志,2016,22(8):632-638.[23]曾炳亮,李滋聪,廖小清,等.双源CT能谱成像技术在肺内孤立性结节良恶性鉴别诊断的应用价值[J].江西医药,2016,51(5):391-394.[24]Wang P,Tang Z,Xiao Z,et al.Dual-energy CT in predicting Ki-67 expression in laryngeal squamous cell carcinoma[J].Eur J Radiol,2021,140:109774.[25]Gong HX,Zhang KB,Wu LM,et al.Dual Energy Spectral CT Imaging for Colorectal Cancer Grading: A Preliminary Study[J].PLoS One,2016,11(2):e0147756.[26]田双凤,田为中,夏建国,等.能谱CT成像技术在不同病理类型实性肺癌中的临床价值[J].交通医学,2021,35(3):287-290.

更新日期/Last Update: 1900-01-01