[1]党佳蓉,党琳慧,郭煦妍,等.糖尿病肾病的发病机制研究[J].医学信息,2022,35(17):161-165.[doi:10.3969/j.issn.1006-1959.2022.17.044]
 DANG Jia-rong,DANG Lin-hui,GUO Xu-yan,et al.Study on Pathogenesis of Diabetic Nephropathy[J].Journal of Medical Information,2022,35(17):161-165.[doi:10.3969/j.issn.1006-1959.2022.17.044]
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糖尿病肾病的发病机制研究()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
35卷
期数:
2022年17期
页码:
161-165
栏目:
综述
出版日期:
2022-09-01

文章信息/Info

Title:
Study on Pathogenesis of Diabetic Nephropathy
文章编号:
1006-1959(2022)17-0161-05
作者:
党佳蓉党琳慧郭煦妍
(陕西中医药大学基础医学院,陕西 咸阳 712046)
Author(s):
DANG Jia-rongDANG Lin-huiGUO Xu-yanet al.
(School of Basic Medicine,Shaanxi University of Traditional Chinese Medicine,Xianyang 712046,Shaanxi,China)
关键词:
糖尿病肾病糖尿病代谢性疾病晚期糖基化终末产物炎症因子
Keywords:
Diabetic nephropathyDiabetes mellitusMetabolic diseasesAdvanced glycation end productsInflammatory factors
分类号:
R587.1
DOI:
10.3969/j.issn.1006-1959.2022.17.044
文献标志码:
A
摘要:
糖尿病肾病(DN)是对患者负担最重的糖尿病(DM)并发症之一,是一种代谢性疾病。目前为止,对糖尿病肾病病理生理机制的研究表明其发病机制是多因素的,且各发病机制之间相互作用共同导致该病的发生发展。本文主要从晚期糖基化终末产物、炎症因子、纤维化、肾素、血脂、活性氧、低氧及高血压等方面对糖尿病肾病的发病机制进行综述,以期为临床医生诊治及干预糖尿病肾病提供参考。
Abstract:
Diabetic nephropathy (DN) is one of the most serious complications of diabetes mellitus (DM), which is a metabolic disease. So far, studies on the pathophysiological mechanism of DN have shown that its pathogenesis is multi-factorial, and the interaction between the pathogenesis leads to the occurrence and development of diabetic nephropathy. This article reviews the pathogenesis of diabetic nephropathy from advanced glycation end products, inflammatory factors, fibrosis, renin, blood lipids, reactive oxygen species, hypoxia and hypertension, in order to provide reference for clinicians to diagnose and treat diabetic nephropathy.

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更新日期/Last Update: 1900-01-01