[1]李函芮,秦丽微.经颅多普勒超声与头颅核磁检查对帕金森病患者的诊断价值[J].医学信息,2023,36(06):106-109.[doi:10.3969/j.issn.1006-1959.2023.06.023]
　LI Han-rui,QIN Li-wei.Diagnostic Value of Transcranial Doppler Ultrasound and Cranial Magnetic Resonance Imaging in Patients with Parkinson’s Disease[J].Journal of Medical Information,2023,36(06):106-109.[doi:10.3969/j.issn.1006-1959.2023.06.023]
点击复制

经颅多普勒超声与头颅核磁检查对帕金森病患者的诊断价值()

医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
36卷
期数:
2023年06期
页码:
106-109
栏目:
论著
出版日期:
2023-03-15

文章信息/Info

Title:
Diagnostic Value of Transcranial Doppler Ultrasound and Cranial Magnetic Resonance Imaging in Patients with Parkinson’s Disease
文章编号:
1006-1959（2023）06-0106-03
作者:
李函芮; 秦丽微
（1.佳木斯市肿瘤医院超声科，黑龙江 佳木斯 154002；2.佳木斯大学附属第一医院超声科，黑龙江 佳木斯 154002）
Author(s):
LI Han-rui; QIN Li-wei
(1.Department of Ultrasound,Jiamusi Tumor Hospital,Jiamusi 154002,Heilongjiang,China;2.Department of Ultrasound,the First Affiliated Hospital of Jiamusi University,Jiamusi 154002,Heilongjiang,China)
关键词:
经颅多普勒超声; 头颅核磁; 帕金森病
Keywords:
Transcranial Doppler ultrasound; Cranial nuclear magnetic resonance; Parkinson’s disease
分类号:
R445.1；R742.5
DOI:
10.3969/j.issn.1006-1959.2023.06.023
文献标志码:
A
摘要:
目的 观察经颅多普勒超声与头颅核磁检查对帕金森病患者的诊断价值。方法 选取2020年1月-2022年2月在佳木斯市肿瘤医院诊治的60例帕金森病患者为研究对象，定义为观察组，并选取同期在我院体检健康者60例为对照组，两组均进行经颅多普勒超声、头颅核磁检查。比较两组患者周围脑组织灰度值、黑质高回声面积、第三脑室宽度、脑桥面积、中脑面积、小脑中脚宽度、不同检测方法帕金森病（异常情况、轻度脑萎缩、腔隙性脑梗死、异常血管）检查结果以及诊断灵敏度、特异度。结果 观察组周围脑组织灰度值、黑质高回声面积均高于对照组（P＜0.05）；两组第三脑室宽度比较，差异无统计学意义（P＞0.05）；观察组脑桥面积、中脑面积、小脑中脚宽度与对照组比较，差异无统计学意义（P＞0.05）；经颅多普勒超声无异常情况、轻度脑萎缩、腔隙性脑梗死检出率与头颅核磁检出率比较，差异无统计学意义（P＞0.05），异常血管检出率高于头颅核磁检出率（P＜0.05）；经颅多普勒超声联合头颅核磁诊断灵敏度高于经颅多普勒超声诊断、头颅核磁诊断，特异度低于经颅多普勒超声诊断、头颅核磁诊断，且经颅多普勒超声诊断灵敏度高于头颅核磁诊断（P＜0.05），两者特异度比较，差异无统计学意义（P＞0.05）。结论 经颅多普勒超声与头颅核磁检查对帕金森病患者均具有一定的诊断价值，相比较而言经颅多普勒超声诊断灵敏度高、操作简单，且特异性无显著差异。
Abstract:
Objective To observe the diagnostic value of transcranial Doppler ultrasound and cranial nuclear magnetic resonance in patients with Parkinson’s disease.Methods From January 2020 to February 2022,60 patients with Parkinson’s disease diagnosed and treated in Jiamusi Tumor Hospital were selected as the observation group, and 60 healthy people who underwent physical examination in our hospital during the same period were selected as the control group. Both groups were examined by transcranial Doppler ultrasound and cranial nuclear magnetic resonance. The gray value of the surrounding brain tissue, the hyperechoic area of the substantia nigra, the width of the third ventricle, the area of the pons, the area of the midbrain, the width of the middle cerebellar peduncle, the results of different detection methods of Parkinson’s disease (abnormal condition, mild brain atrophy, lacunar infarction, abnormal blood vessels) and the diagnostic sensitivity and specificity were compared between the two groups.Results The gray value of the surrounding brain tissue and the hyperechoic area of the substantia nigra in the observation group were higher than those in the control group (P<0.05). There was no significant difference in the width of the third ventricle between the two groups (P＞0.05). There was no significant difference in pons area, midbrain area and cerebellar peduncle width between the observation group and the control group (P＞0.05). There was no significant difference in the detection rate of no abnormality, mild brain atrophy and lacunar infarction between transcranial Doppler ultrasound and cranial nuclear magnetic resonance (P＞0.05). The detection rate of abnormal blood vessels by transcranial Doppler ultrasound was higher than that by cranial nuclear magnetic resonance (P<0.05). The diagnostic sensitivity of transcranial Doppler ultrasound combined with cranial nuclear magnetic resonance was higher than that of transcranial Doppler ultrasound and cranial nuclear magnetic resonance alone, and the specificity was lower than that of transcranial Doppler ultrasound and cranial nuclear magnetic resonance alone, and the diagnostic sensitivity of transcranial Doppler ultrasound was higher than that of cranial nuclear magnetic resonance (P<0.05). There was no significant difference in specificity between the two (P＞0.05).Conclusion Transcranial Doppler ultrasound and cranial nuclear magnetic resonance examination have certain diagnostic value for patients with Parkinson’s disease. In comparison, transcranial Doppler ultrasound has high diagnostic sensitivity, simple operation, and no significant difference in specificity.

参考文献/References:

[1]Zhao XJ,Chi JH,Fan XY,et al.Application of Transcranial Doppler Sonography in the Early Diagnosis of Parkinson’s Disease[J].China & Foreign Medical Treatment,2017,15(13):112-113.[2]乔亚男,薛爽,顾卫红,等.帕金森病患者经颅脑实质超声所见与临床评价[J].中风与神经疾病,2016,33(3):226-229.[3]郑朋楼,杨斌,刘玲.帕金森病早期诊断的影像技术应用[J].中国中西医结合影像学杂志,2016,14(3):363-366.[4]张巍.经颅黑质超声与帕金森病的诊断及评估[J].诊断学理论与实践,2016(2):108-112.[5]董智芬,张迎春,盛余敬.帕金森病与阿尔茨海默病患者的经颅超声图像分析[J].中国医学影像技术,2017,14(2):178-180.[6]张丽.黑质回声与帕金森病的相关性分析[D].长春:吉林大学,2017.[7]中华医学会神经病学分会帕金森病及运动障碍学组,中国医师协会神经内科医师分会帕金森病及运动障碍专业委员会.中国帕金森病的诊断标准(2016 版)[J].中华神经科杂志,2016,49(4):268-271.[8]Yu SY,Cao CJ,Zuo LJ,et al.Clinical features and dysfunctions of iron metabolism in Parkinson disease patients with hyper echogenicity in substantia nigra: a cross-sectional study [J].BMC Neurol,2018,18(1):9.[9]贺伟光,范国华,罗蔚锋,等.多系统萎缩和帕金森病患者的磁共振影像学分析[J].中华老年医学杂志,2018(3):203-207.[10]唐北沙,陈生弟.中华医学会神经病学分会帕金森病及运动障碍学组.多系统萎缩诊断标准中国专家共识[J].中国综合临床,2018,34(5):385-389.[11]Moteri BLGA,Aslam M.Thyrotoxic periodic paralysis:a case report[J].International Journal of Health Sciences,2017,11(1):1-2.[12]孙逊,刘芳,阮伟伟,等.帕金森综合征PET/MR同步采集18F-FDG显像与ASL脑血流灌注成像相关性及鉴别诊断价值[J].中华核医学与分子影像杂志,2019,39(6):337-343.[13]马敬红,叶铮,马绍扬,等.早期帕金森病、多系统萎缩及进行性核上性麻痹理查森型工作记忆损害的比较[J].临床神经病学杂志,2019,32(4):245-248.[14]江名芳,牛广明,石峰.氢质子磁共振波谱在帕金森病诊断中的应用研究[J].疑难病杂志,2017,14(10):52-53.[15]管晓军,谢非,徐晓俊.定量磁敏感图黑质“燕尾征”在帕金森病诊断中的应用价值[J].中国现代神经疾病杂志,2018,13(4):247-251.[16]周雯,徐德敏,张辉,等.颅脑MRI在帕金森病与帕金森综合征、多系统萎缩、进行性核上性麻痹鉴别诊断的意义[J].罕少疾病杂志,2021,28(8):13-15.[17]于文文,王琦,吴晓丽.经颅超声和MRI对多系统萎缩与帕金森病患者的鉴别诊断价值[J].医学影像学杂志,2021,31(1):119-121.[18]彭素丹,陈颖,井秀娜,等.帕金森病与帕金森叠加综合征MRI中脑结构测量学特点及临床相关性研究[J].岭南急诊医学杂志,2021,20(10):101-103.[19]胡火有,韩漫夫,熊华花,等.经颅超声在诊断和鉴别诊断帕金森病中的应用及黑质回声与临床特征的关系研究[J].中国微侵袭神经外科杂志,2016,20(9):392-384.[20]吴大鹏,汪慧,盛灿,等.经颅多普勒超声黑质检测对帕金森病的诊断意义[J].卒中与神经疾病,2018,25(8):461-463.

相似文献/References:

[1]边 际.TCD血流动力学指标评价急性脑梗死患者认知功能损伤程度的价值[J].医学信息,2019,32(24):54.[doi:10.3969/j.issn.1006-1959.2019.24.017]
　BIAN Ji.Value of TCD Hemodynamic Index in Evaluating the Degree of Cognitive Impairment in Patients with Acute Cerebral Infarction[J].Journal of Medical Information,2019,32(06):54.[doi:10.3969/j.issn.1006-1959.2019.24.017]
[2]李函芮,秦丽薇.经颅多普勒超声对血管性帕金森病和原发性帕金森病的鉴别诊断价值[J].医学信息,2023,36(05):143.[doi:10.3969/j.issn.1006-1959.2023.05.028]
　LI Han-rui,QIN Li-wei.The Value of Transcranial Doppler Ultrasound in the Differential Diagnosis of Vascular Parkinson’s Disease and Primary Parkinson’s Disease[J].Journal of Medical Information,2023,36(06):143.[doi:10.3969/j.issn.1006-1959.2023.05.028]
[3]陈 艳,赵文芳,柳 芊.颈动脉超声联合经颅多普勒超声在缺血性脑血管疾病中的应用价值[J].医学信息,2023,36(13):119.[doi:10.3969/j.issn.1006-1959.2023.13.024]
　CHEN Yan,ZHAO Wen-fang,LIU Qian.Application Value of Carotid Ultrasound Combined with Transcranial Doppler Ultrasound in Ischemic Cerebrovascular Disease[J].Journal of Medical Information,2023,36(06):119.[doi:10.3969/j.issn.1006-1959.2023.13.024]
[4]胡甜甜.经颅多普勒超声联合颈动脉超声在老年脑梗死患者血管病变评估中的效果[J].医学信息,2026,39(03):114.[doi:10.3969/j.issn.1006-1959.2026.03.021]
　HU Tiantian.Effect of Transcranial Doppler Ultrasound Combined with Carotid Duplex Ultrasonographyin the Evaluation of Vascular Lesions in Elderly Patients with Cerebral Infarction[J].Journal of Medical Information,2026,39(06):114.[doi:10.3969/j.issn.1006-1959.2026.03.021]

更新日期/Last Update: 1900-01-01