[1]涂志超.限制输血与积极输血治疗急性上消化道出血的疗效比较[J].医学信息,2023,36(11):91-94.[doi:10.3969/j.issn.1006-1959.2023.11.016]
　TU Zhi-chao.Efficacy Comparison of Restrictive Blood Transfusion and Active Blood Transfusion in the Treatment of Acute Upper Gastrointestinal Bleeding[J].Journal of Medical Information,2023,36(11):91-94.[doi:10.3969/j.issn.1006-1959.2023.11.016]
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限制输血与积极输血治疗急性上消化道出血的疗效比较()

医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
36卷
期数:
2023年11期
页码:
91-94
栏目:
论著
出版日期:
2023-06-01

文章信息/Info

Title:
Efficacy Comparison of Restrictive Blood Transfusion and Active Blood Transfusion in the Treatment of Acute Upper Gastrointestinal Bleeding
文章编号:
1006-1959（2023）11-0091-04
作者:
涂志超
（井冈山大学附属医院输血科，江西 吉安 343000）
Author(s):
TU Zhi-chao
(Department of Blood Transfusion,Jinggangshan University Affiliated Hospital,Ji’an 343000,Jiangxi,China)
关键词:
限制输血; 积极输血; 急性上消化道出血; 凝血功能
Keywords:
Restrictive blood transfusion; Active blood transfusion; Acute upper gastrointestinal bleeding; Coagulation function
分类号:
R457.1；R573.2
DOI:
10.3969/j.issn.1006-1959.2023.11.016
文献标志码:
A
摘要:
目的 比较限制输血与积极输血治疗急性上消化道出血的疗效。方法 选取2021年1月-2022年10月我院诊治的80例急性上消化道出血患者为研究对象，采用随机数字表法分为对照组和观察组，各组40例。对照组采用积极输血治疗，观察组采用限制输血治疗，比较两组止血效果、凝血功能指标[活化部分凝血活酶时间（APTT）、凝血酶原时间（PT）、纤维蛋白原（FIB）、凝血酶时间（TT）]、血液流变学（红细胞比容、血浆黏度）、再出血危险（Blatchford）评分以及不良反应发生率。结果 观察组止血成功率为95.00%，高于对照组的82.50%（P＜0.05）；观察组治疗后APTT、PT、TT均低于对照组，FIB高于对照组（P＜0.05）；观察组治疗后红细胞比容、血浆黏度均高于对照组（P＜0.05）；治疗3 d后，观察组Blatchford评分低于对照组（P＜0.05）；观察组不良反应发生率低于对照组（P＜0.05）。结论 与积极输血治疗比较，限制输血治疗急性上消化道出血的效果确切，可提高止血效果，改善凝血功能及血液流变学指标，降低再出血风险、不良反应发生率，值得临床应用。
Abstract:
Objective To compare the efficacy of restrictive blood transfusion and active blood transfusion in the treatment of acute upper gastrointestinal bleeding.Methods A total of 80 patients with acute upper gastrointestinal bleeding diagnosed and treated in our hospital from January 2021 to October 2022 were selected as the research objects. They were divided into control group and observation group by random number table method, with 40 patients in each group. The control group was treated with active blood transfusion, and the observation group was treated with restrictive blood transfusion. The hemostatic effect, coagulation function indexes [activated partial thromboplastin time (APTT), prothrombin time (PT), fibrinogen (FIB), thrombin time (TT)], hemorheology (hematocrit, plasma viscosity), rebleeding risk (Blatchford) score and incidence of adverse reactions were compared between the two groups.Results The success rate of hemostasis in the observation group was 95.00%, which was higher than 82.50% in the control group (P<0.05). After treatment, APTT, PT and TT in the observation group were lower than those in the control group, and FIB was higher than that in the control group (P<0.05). After treatment, the hematocrit and plasma viscosity of the observation group were higher than those of the control group (P<0.05). After 3 days of treatment, the Blatchford score of the observation group was lower than that of the control group (P<0.05). The incidence of adverse reactions in the observation group was lower than that in the control group (P<0.05).Conclusion Compared with active blood transfusion, restrictive blood transfusion is effective in the treatment of acute upper gastrointestinal bleeding. It can improve the hemostatic effect, improve the coagulation function and hemorheology indexes, reduce the risk of rebleeding and the incidence of adverse reactions, which is worthy of clinical application.

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更新日期/Last Update: 1900-01-01