参考文献/References:
[1]Neves LPP,Marcondes RR,Maffazioli GN,et al.Nutritional and dietary aspects in polycystic ovary syndrome: insights into the biology of nutritional interventions[J].Gynecol Endocrinol,2020,36(12):1047-1050.[2]曹梦娣.补肾健脾法改善PCOS慢性低度炎症状态的疗效及其与肥胖相关性的研究[D].南京:南京中医药大学,2021.[3]Hopkins AL.Network pharmacology:The next paradigm in drug discovery[J].Nature Chemical Biology,2008,4(11):682-690.[4]韩聪,夏铭鸿,胡渊龙,等.基于网络药理学和分子对接分析续断-桑寄生改善多囊卵巢综合征作用的机制[J].山东科学,2022,35(3):7-16.[5]袁仁智,唐鹏,肖卫琼,等.当归-菟丝子干预肾虚血瘀型多囊卵巢综合征网络药理学作用机制[J].新中医,2020,52(3):83-88.[6]肖卫琼,袁仁智,康开彪.半夏-苍术-香附组药干预痰湿型多囊卵巢综合征的生物机制[J].中医药导报,2020,26(13):144-150.[7]侯阿美,储继军.基于数据挖掘的中医药治疗多囊卵巢综合征的用药规律分析[J].西南医科大学学报,2021,44(4):392-398.[8]Szklarczyk D,Gable AL,Lyon D,et al.STRING v11: protein-protein association networks with increased coverage, supporting functional discovery in genome-wide experimental datasets[J].Nucleic Acids Res,2019,47(D1):D607-D613.[9]Zhou Y,Zhou B,Pache L,et al.Metascape provides a biologist-oriented resource for the analysis of systems-level datasets[J].Nat Commun,2019,10(1):1523.[10]郭灵娜.补肾化痰汤联合二甲双胍治疗多囊卵巢综合征临床观察[J].光明中医,2022,37(16):3003-3005.[11]刘畅.补肾健脾方对多囊卵巢综合征患者行体外受精-胚胎移植助孕后妊娠结局的影响[D].杭州:浙江中医药大学,2022.[12]李燕,陈素红,吉星,等.白术多糖对自发性2型糖尿病小鼠血糖及相关指标的影响[J].中国实验方剂学杂志,2015,21(10):162-165.[13]柯江维,王建红,赵宏.菟丝子黄酮对心理应激雌性大鼠海马-下丘脑-垂体-卵巢轴性激素受体的影响[J].中草药,2006,37(1):90-92.[14]Shah KN,Patel SS.Phosphatidylinositide 3-kinase inhibition: A new potential target for the treatment of polycystic ovarian syndrome[J].Pharm Biol,2016,54(6):975-983.[15]Mihanfar A,Nouri M,Roshangar L,et al.Therapeutic potential of quercetin in an animal model of PCOS: Possible involvement of AMPK/SIRT-1 axis[J].Eur J Pharmacol,2021,900:174062.[16]Santos JMS,Monte APO,TLBGLins,et al.Kaempferol can be used as the single antioxidant in the in vitro culture medium, stimulating sheep secondary follicle development through the phosphatidylinositol 3-kinase signaling pathway[J].Theriogenology,2019.136:86-94.[17]Jiang H,Yamashita Y,Nakamura A,et al.Quercetin and its metabolite isorhamnetin promote glucose uptake through different signalling pathways in myotubes[J].Sci Rep,2019,9(1):2690.[18]Nekoonam S,Naji M,Nashtaei MS,et al.Expression of AKT1 along with AKT2 in granulosa-lutein cells of hyperandrogenic PCOS patients[J].Arch GynecolObstet,2017,295(4):1041-1050.[19]Goto M,Iwase A,Ando H,et al.PTEN and Akt expression during growth of human ovarian follicles[J].J Assist Reprod Genet,2007,24(11):541-546.[20]Chen WS,Peng XD,Wang Y,et al.Leptin deficiency and beta-cell dysfunction underlie type 2 diabetes in compound Akt knockout mice[J].Mol Cell Biol,2009,29(11):3151-3162.[21]George S,Rochford JJ,Wolfrum C,et al.A family with severe insulin resistance and diabetes due to a mutation in AKT2[J].Science,2004,304(5675):1325-1328.[22]van Dijk TH,Laskewitz AJ,Grefhorst A,et al.A novel approach to monitor glucose metabolism using stable isotopically labelled glucose in longitudinal studies in mice[J].Lab Anim,2013,47(2):79-88.[23]Monden M,Koyama H,Otsuka Y,et al.Receptor for advanced glycation end products regulates adipocyte hypertrophy and insulin sensitivity in mice: involvement of Toll-like receptor 2[J].Diabetes,2013,62(2):478-489.[24]Foroozanfard F,Soleimani A,Arbab E,et al.Relationship between IL-17 serum level and ambulatory blood pressure in women with polycystic ovary syndrome[J].J Nephropathol,2017,6(1):15-24.[25]Xie Q,Xiong X,Xiao N,et al.Mesenchymal Stem Cells Alleviate DHEA-Induced Polycystic Ovary Syndrome (PCOS) by Inhibiting Inflammation in Mice[J].Stem Cells Int,2019,2019:9782373.