[1]陈燕红,张继州,蒋 畅,等.基于数据挖掘分析含天花粉成方制剂的组方规律[J].医学信息,2024,37(08):10-16.[doi:10.3969/j.issn.1006-1959.2024.08.002]
 CHEN Yan-hong,ZHANG Ji-zhou,JIANG Chang,et al.The Prescription Rule of Prescription Preparation Containing Radix Trichosanthis Based on Data mining[J].Journal of Medical Information,2024,37(08):10-16.[doi:10.3969/j.issn.1006-1959.2024.08.002]
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基于数据挖掘分析含天花粉成方制剂的组方规律()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
37卷
期数:
2024年08期
页码:
10-16
栏目:
中医药信息学
出版日期:
2024-04-15

文章信息/Info

Title:
The Prescription Rule of Prescription Preparation Containing Radix Trichosanthis Based on Data mining
文章编号:
1006-1959(2024)08-0010-07
作者:
陈燕红张继州蒋 畅
(1.福建中医药大学药学院,福建 福州 350122;2.福建省中医药科学院,福建 福州 350003)
Author(s):
CHEN Yan-hongZHANG Ji-zhouJIANG Changet al.
(1.College of Pharmacy,Fujian University of Traditional Chinese Medicine,Fuzhou 350122,Fujian,China; 2.Fujian Academy of Chinese Medical Science,Fuzhou 350003,Fujian,China)
关键词:
天花粉中药成方制剂中医传承计算平台组方规律
Keywords:
Radix TrichosanthisPreparation of traditional Chinese medicine prescriptionTraditional Chinese Medicine Inheritance Computing SystemPrescription rules
分类号:
R285
DOI:
10.3969/j.issn.1006-1959.2024.08.002
文献标志码:
A
摘要:
目的 基于中医传承计算平台(TCMICS)分析《中华人民共和国卫生部药品标准 中药成方制剂》(简称《中药成方制剂》)含天花粉方剂组方规律,为临床应用及新药研发提供参考。方法 运用中医传承计算平台(V3.0)软件,收集《中药成方制剂》中含天花粉方剂,整理后采用频次统计、关联规则等数据挖掘方法,对主治疾病、常用药对及组方规律进行分析,并对高频疾病和高频药对进行分析。结果 共获得含天花粉方剂143首,涉及中药352味,主治疾病80种。其中,与天花粉合用药物多为清热解毒、化痰止咳平喘药如甘草、桔梗、黄芩、玄参等。高频主治疾病为咳嗽、感冒、喉痹、消渴等,且用于治疗的高频药物组合与疾病的临床治则基本一致。结论 《中药成方制剂》中含天花粉方剂多具有清热生津、化痰止咳之功效。
Abstract:
bjective To analyze the prescription rules of formulae containing Radix Trichosanthis in Pharmaceutical Standard of the Ministry of Health of People’s Republic of China-Preparation of Traditional Chinese Medicine Prescription (Hereinafter referred to as Preparation of Traditional Chinese Medicine Prescription) based on Traditional Chinese Medicine Inheritance Computing System (TCMICS), then provide reference for clinical application and researching and inventing in new Chinese medicine.Methods Through TCMICS (V3.0), formulae containing Radix Trichosanthis in Preparation of Traditional Chinese Medicine Prescription were collected and organized. Data mining methods, such as frequency statistics, association rules and others, were used to analyze attending diseases, compatibility with commonly used drugs and combination rules, and to conduct in-depth analysis of high-frequency diseases and medicine pairs.Results There were a total of 143 prescriptions containing Radix Trichosanthis, involving 352 kinds of traditional Chinese medicine and 80 attending diseases. Among them, most of the drugs used in combination with Radix Trichosanthis were heat-clearing and detoxifying, phlegm-eliminating and cough-alleviating drugs such as licorice, Platycodon grandiflorum, Radix Scutellariae, Radix Scrophulariae. The high frequency attending diseases were cough, influenza, pharyngitis, diabetes, and the combination of high-frequency drugs used for treatment was basically consistent with the clinical rule of the disease.Conclusion The formulae containing Radix Trichosanthis in Preparation of Traditional Chinese Medicine Prescription have the effect of clearing heat, promoting fluid, dissolving phlegm and relieving cough.

参考文献/References:

[1]国家药典委员会.中华人民共和国药典:一部[M].北京:中国医药科技出版社,2020:57.[2]王宁.天花粉的本草考证[J].中医文献杂志,2006,24(3):19-22. [3]中华人民共和国卫生部药典委员会.中华人民共和国卫生部药品标准 中药成方制剂[M].北京:中华人民共和国卫生部药典委员会,1995.[4]宋宁,王新苗,樊俐慧,等.天花粉的临床应用及其用量探究[J].长春中医药大学学报,2020,36(3):433-435.[5]张秋艳,黄松丽,张琳婧,等.黄芪和天花粉对小鼠恶性黑色素瘤B16细胞增殖和迁移及E-cadherin、N-cadherin蛋白表达的影响[J].中国中医药信息杂志,2020,27(5):28-34.[6]戴良图,张华,王晨曦,等.天花粉蛋白治疗异位妊娠的临床应用及不良反应分析[J].海军医学杂志,2013,34(5):321-324.[7]刘巧,胡俊媛,王俭,等.中药天花粉对人恶性黑色素瘤细胞凋亡及Caspase-3活性的影响[J].中华中医药杂志,2015,30(2):534-536.[8]周凌,张伟,张子微,等.重构本草——天花粉[J].吉林中医药,2023,43(3):335-337.[9]赵洪伟,张宁,李自辉,等.解析玄参利水功效的古存今失[J].中医药信息,2018,35(2):24-27.[10]李琼,叶小利,陈新,等.天花粉降糖作用有效部位的研究[J].长春中医药大学学报,2012,28(1):9-11.[11]龚道锋,王甫成,纪东汉,等.不同产地天花粉中15种氨基酸的测定[J].中成药,2019,41(03):607-613.[12]张晓敏,牛宪立,魏妮娜,等.天花粉对糖尿病大鼠降糖作用的研究[J].中国民族民间医药,2020,29(7):13-16.[13]刘琼,李兵,雷蕾,等.基于数据挖掘分析已上市中成药治疗糖尿病及其微血管并发症的用药规律[J].中国中医药信息杂志,2021,28(5):25-31.[14]欧阳璐斯,夏婷,陶红,等.栝楼不同部位对卷烟烟气总粒相物诱导人支气管上皮细胞增殖及炎症因子表达的影响[J].中药新药与临床药理,2021,32(2):219-225.[15]邹纯才,吕文雅,周雨婷,等.瓜蒌薤白配伍抗凝血作用的研究[J].通化师范学院学报,2018,39(12):15-17,64.[16]张宇,姜德友.龙江医派马骥教授治疗咳嗽经验[J].西部中医药,2018,31(10):16-18.[17]章小红,杨宏志.《医学入门》论治咳嗽[J].江西中医药,2023,54(1):1-3,6.[18]高越,刘施,黄正德,等.含半夏中成药组方规律[J].医药导报,2019,38(12):1645-1651.[19]王冰.基于现代名老中医经验的流行性感冒辨证与方药规律研究[D].郑州:河南中医药大学,2016.[20]刘坚辉,陈楚仪,杨帏勋,等.基于网络药理学探析玉液汤对2型糖尿病的作用机制[J].中成药,2021,43(9):2534-2539.[21]李依诺,谷峰,杨宇峰,等.基于《黄帝内经》理论探究消渴病病因病机与治疗[J].实用中医内科杂志,2022,36(2):32-34.

更新日期/Last Update: 1900-01-01