[1]杨 俊.C反应蛋白、SAA对尿毒症透析患者微炎症状态的诊断价值[J].医学信息,2024,37(23):159-162.[doi:10.3969/j.issn.1006-1959.2024.23.038]
　YANG Jun.Diagnostic Value of C-reactive Proteinand SAA in Micro-inflammatory State of Uremic Dialysis Patients[J].Journal of Medical Information,2024,37(23):159-162.[doi:10.3969/j.issn.1006-1959.2024.23.038]
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C反应蛋白、SAA对尿毒症透析患者微炎症状态的诊断价值()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
37卷
期数:
2024年23期
页码:
159-162
栏目:
诊疗技术
出版日期:
2024-12-01

文章信息/Info

Title:
Diagnostic Value of C-reactive Proteinand SAA in Micro-inflammatory State of Uremic Dialysis Patients
文章编号:
1006-1959（2024）23-0159-04
作者:
杨 俊
上饶市中医院检验科，江西 上饶 334000
Author(s):
YANG Jun
Laboratory Department of Shangrao Hospital of Traditional Chinese Medicine,Shangrao 334000,Jiangxi,China
关键词:
尿毒症; 血液透析; 微炎症状态; C-反应蛋白; 血清淀粉样蛋白A
Keywords:
Hemodialysis; Micro-inflammatory state; C-reactive protein; Serum amyloid protein A
分类号:
R446
DOI:
10.3969/j.issn.1006-1959.2024.23.038
文献标志码:
A
摘要:
目的 研究C-反应蛋白（CRP）与血清淀粉样蛋白A（SAA）对尿毒症透析患者微炎症状态的诊断价值。方法 以2022年1月-2023年11月于上饶市中医院行透析治疗的60例尿毒症患者为研究对象，将存在微炎症状态的34例患者设为微炎症组，非炎症患者26例设为非炎症组，均行CRP、SAA检测。比较尿毒症患者透析前与透析后的CRP、SAA水平，对比微炎症组与非炎症组患者CRP、SAA水平；绘制受试者工作特征曲线（ROC），分析CRP、SAA对尿毒症透析患者微炎症状态的诊断价值。结果 尿毒症患者透析后CRP、SAA水平高于透析前（P＜0.05）；微炎症组CRP、SAA水平高于非炎症组（P＜0.05）；ROC曲线显示，CRP、SAA对尿毒症透析患者微炎症状态具有确切诊断价值（AUC＞0.5，P＜0.05），且两者联合检测的AUC值高于其单独检测（P＜0.05）。结论 CRP、SAA对尿毒症透析患者微炎症状态具有确切诊断价值，两者联合检测诊断效能更高。
Abstract:
Objective To study the diagnostic value of C-reactive protein (CRP) and serum amyloid A (SAA) for microinflammatory state in uremic dialysis patients.Methods From January 2022 to November 2023,60 patients with uremia who underwent dialysis treatment in Shangrao Hospital of Traditional Chinese Medicine were selected as the research objects. 34 patients with micro-inflammatory state were set as micro-inflammatory group, and 26 patients with non-inflammatory state were set as non-inflammatory group. CRP and SAA were detected in all patients. The levels of CRP and SAA in uremic patients before and after dialysis were compared. The levels of CRP and SAA in the micro-inflammatory group and the non-inflammatory group were compared. The receiver operating characteristic curve (ROC) was drawn to analyze the diagnostic value of CRP and SAA in the micro-inflammatory state of uremic dialysis patients.Results The levels of CRP and SAA in uremic patients after dialysis were higher than those before dialysis (P<0.05). The levels of CRP and SAA in the micro-inflammation group were higher than those in the non-inflammation group (P<0.05). ROC curve showed that CRP and SAA had definite diagnostic value for microinflammatory state in uremic dialysis patients (AUC>0.5, P<0.05), and the AUC value of combined detection was higher than that of single detection (P<0.05).Conclusion CRP and SAA have definite diagnostic value for micro-inflammatory state in uremic dialysis patients, and the combined detection of CRP and SAA has higher diagnostic efficiency.

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更新日期/Last Update: 1900-01-01