[1]肖 阳,姜 波,龚 之.古方治疗轻度认知障碍的用药规律[J].医学信息,2025,38(02):29-32.[doi:10.3969/j.issn.1006-1959.2025.02.004]
 XIAO Yang,JIANG Bo,GONG Zhi,et al.Medication Rules of Ancient Prescriptions in the Treatment of Mild Cognitive Impairment[J].Journal of Medical Information,2025,38(02):29-32.[doi:10.3969/j.issn.1006-1959.2025.02.004]
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古方治疗轻度认知障碍的用药规律()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
38卷
期数:
2025年02期
页码:
29-32
栏目:
中医药信息学
出版日期:
2025-01-15

文章信息/Info

Title:
Medication Rules of Ancient Prescriptions in the Treatment of Mild Cognitive Impairment
文章编号:
1006-1959(2025)02-0029-04
作者:
肖 阳1姜 波12龚 之2
1.浙江中医药大学第三临床医学院,浙江 杭州 310053;2.舟山市中医院康复科,浙江 舟山 316099
Author(s):
XIAO Yang1 JIANG Bo1 2 GONG Zhi2
1.The Third Clinical Medical College of Zhejiang Chinese Medical University, Hangzhou 310053, Zhejiang, China;2.Rehabilitation Department of Zhoushan Hospital of Traditional Chinese Medicine, Zhoushan 316099, Zhejiang, China
关键词:
轻度认知障碍古方数据挖掘理论中医传承辅助平台用药规律
Keywords:
Mild cognitive impairment Ancient prescription Data mining theory Trasitional Chinese medicine inheritance auxiliary platform Medication rules
分类号:
R743
DOI:
10.3969/j.issn.1006-1959.2025.02.004
文献标志码:
A
摘要:
目的 研究古方治疗轻度认知障碍的用药规律。方法 收集《中华医典》中治疗轻度认知障碍的所有古方,应用中医药传承辅助平台进行药频分析、性味分析、归经分析、关联规则分析和新方分析。结果 共包括94个治疗轻度认知障碍的古方,其中包括146种中药。药性主要是温性药物,其次是寒性和平性药物;药味以甘为主,其次是苦味和辛味;药物的归经主要是心经,其次为脾经、肺经、肾经;常用药物有人参、远志、石菖蒲、茯苓、茯神等;提取17个核心药物组合;得到5首治疗轻度认知障碍的新方。结论 古方治疗轻度认知障碍以补虚为主,佐以安神、化痰类药物。
Abstract:
Objective To study the medication rules of ancient prescriptions in the treatment of mild cognitive impairment. Methods All ancient prescriptions for the treatment of mild cognitive impairment in Chinese Medical Classics were collected, and the traditional Chinese medicine inheritance auxiliary platform was used for frequency analysis, taste analysis, meridian tropism analysis, association rule analysis and new prescription analysis. Results A total of 94 ancient prescriptions for the treatment of mild cognitive impairment were included, including 146 traditional Chinese medicines. The medicinal properties were mainly warm drugs, followed by cold and peaceful drugs; the flavor of the medicine was mainly sweet, followed by bitter and pungent; the channel tropism of drugs was mainly the heart channel, followed by the spleen channel, the lung channel and the kidney channel; commonly used drugs were Rensheng, Yuanzhi, Shichangpu, Fuling, Fushen, etc.; extract 17 core drug combinations; five new prescriptions for the treatment of mild cognitive impairment were obtained. Conclusion In the treatment of mild cognitive impairment, the ancient prescription is mainly tonic, supplemented by sedative and expectorant drugs.

参考文献/References:

[1]Anderson ND.State of the science on mild cognitive impairment (MCI)[J].CNS Spectrums,2019,24(1):78-87.[2]Martin E,Velayudhan L.Neuropsychiatric Symptoms in Mild Cognitive Impairment: A Literature Review[J].Dement Geriatr Cogn Disord,2020,49(2):146-155.[3]Wang KN,Page AT,Etherton-Beer CD.Mild cognitive impairment: To diagnose or not to diagnose[J].Australas J Ageing,2021,40(2):111-115.[4]彭雯洁,秦瑶,韩红娟,等.轻度认知障碍转化为阿尔茨海默病的生存分析[J].现代预防医学,2020,47(16):2891-2894,2932.[5]Petersen RC,Lopez O,Armstrong MJ.Practice guideline update summary: Mild cognitive impairment: Report of the Guideline Development, Dissemination, and Implementation Subcommittee of the American Academy of Neurology[J].Neurology,2018,90(3):126-135.[6]马睛雅.老年轻度认知障碍非药物干预患者指南及患者决策辅助工具的构建[D].北京:北京协和医学院,2024.[7]饶志娟.康复护理在老年痴呆症患者中的应用价值[J].医学信息,2019,32(12):188-190.[8]Sanford AM.Mild Cognitive Impairment[J].Clin Geriatr Med,2017,33(3):325-337.[9]常诚,王昕,符为民,等.痴呆的中医病名探析[J].中医杂志,2014,55(24):2078-2080.[10]朱俊秀,闻永毅.基于《中国中医古籍总目》的数据挖掘[J].西部中医药,2023,36(4):35-38.[11]南京中医药大学.中药大辞典[M].上海:上海科学技术出版社,2006.[12]李娜娜,张芮铭,沙中玮,等.基于“浊邪害清”理论探讨轻度认知障碍的病机与辨治[J].中医杂志,2023,64(4):346-349.[13]沈英,黄小波.水火既济组方治疗卒中后轻度认知功能障碍临床研究[J].河北中医药学报,2019,34(2):14-17.[14]瞿融,马世平,詹莹,等.定志小丸对老龄大鼠学习记忆能力的影响[J].中国临床康复,2004,8(4):684-685.[15]雷贤明,曹云涛,杨洁,等.人参皂苷Rd对新生鼠脑室周围白质软化模型学习记忆的影响[J].现代医药卫生,2023,39(15):2539-2543,2548.[16]徐甜,马重阳,邓楠,等.基于网络药理学探讨人参茯苓药对治疗老年性痴呆的作用机制[J].中医杂志,2019,60(22):1957-1963.[17]孙灵芝,艾邸.菖蒲-远志药对组分对Aβ1-42诱导PC12细胞凋亡和钙离子浓度的影响[J].中西医结合心脑血管病杂志,2020,18(18):2991-2995.[18]徐青青,朱斌,计静,等.健脾化痰方联合认知训练治疗帕金森病轻度认知障碍临床研究[J].新中医,2023,55(17):91-95.[19]梅雪迎.健脾养心汤治疗老年性痴呆(心脾两虚型)的临床观察[D].郑州:河南中医药大学,2017.[20]李卉,张艳.人参皂苷与远志皂苷配伍治疗大鼠阿尔茨海默病的作用研究[J].吉林化工学院学报,2018,35(7):66-70.

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更新日期/Last Update: 1900-01-01