[1]王梦琳,周燕子,邱咪咪,等.金匮肾气汤加减治疗脾肾阳虚型糖尿病肾病的效果[J].医学信息,2025,38(02):144-148.[doi:10.3969/j.issn.1006-1959.2025.02.028]
　WANG Menglin,ZHOU Yanzi,QIU Mimi,et al.Effect of Modified Jingui Shenqi Decoction in the Treatment of Diabetic Nephropathy of Spleen and Kidney Yang Deficiency Type[J].Journal of Medical Information,2025,38(02):144-148.[doi:10.3969/j.issn.1006-1959.2025.02.028]
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金匮肾气汤加减治疗脾肾阳虚型糖尿病肾病的效果()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
38卷
期数:
2025年02期
页码:
144-148
栏目:
论著
出版日期:
2025-01-15

文章信息/Info

Title:
Effect of Modified Jingui Shenqi Decoction in the Treatment of Diabetic Nephropathy of Spleen and Kidney Yang Deficiency Type
文章编号:
1006-1959（2025）02-0144-05
作者:
王梦琳1; 周燕子1; 邱咪咪2; 黄晓鹏1; 刘丽秀3
吉水县人民医院肾内科1，内分泌风湿免疫科2，血透室3，江西 吉水 331600
Author(s):
WANG Menglin1;  ZHOU Yanzi1;  QIU Mimi2;  HUANG Xiaopeng1;  LIU Lixiu3
Department of Renal Medicine1, Department of Endocrine, Rheumatology Immunology2, Hemodialysis Room3, Jishui County People’s Hospital， Jishui 331600, Jiangxi, China
关键词:
金匮肾气汤; 加减; 脾肾阳虚型; 糖尿病肾病
Keywords:
Jinkui Shenqi decoction;  Modified;  Spleen and kidney yang deficiency type;  Diabetic nephropathy
分类号:
R587.2
DOI:
10.3969/j.issn.1006-1959.2025.02.028
文献标志码:
A
摘要:
目的 分析金匮肾气汤加减治疗脾肾阳虚型糖尿病肾病的效果。方法 选取吉水县人民医院2021年1月-2023年6月收治的60例脾肾阳虚型糖尿病肾病患者作为研究对象，按照随机数字表法分为对照组和研究组，各30例。对照组采取常规西医干预，研究组予以金匮肾气汤加减治疗。比较两组患者治疗有效率、肾功能[尿素氮（BUN）、24 h蛋白尿、肌酐（Scr）、肾小球滤过率（eGFR）、尿白蛋白排泄率（UAER）]、水肿程度（体质量、腹围、尿量、夜尿次数）及中医症候积分。结果 研究组治疗总有效率高于对照组（P＜0.05）。研究组治疗后UAER、24 h蛋白尿、Scr、BUN水平低于对照组（P＜0.05）；研究组eGFR水平高于对照组（P＜0.05）；研究组体质量、腰围、夜尿次数低于对照组（P＜0.05）；研究组尿量高于对照组（P＜0.05）。研究组中医症候积分低于对照组（P＜0.05）。结论 金匮肾气汤加减治疗脾肾阳虚型糖尿病肾病的效果确切，能够改善患者肾功能，减轻患者水肿程度和中医症候积分，值得临床应用。
Abstract:
Objective To analyze the effect of modified Jinkui Shenqi decoction in the treatment of diabetic nephropathy with spleen and kidney yang deficiency. Methods A total of 60 patients with diabetic nephropathy of spleen and kidney yang deficiency type admitted to Jishui County People’s Hospital from January 2021 to June 2023 were selected as the research objects. According to the random number table method, they were divided into control group and study group, with 30 patients in each group. The control group was treated with routine western medicine intervention, and the study group was treated with modified Jinkui Shenqi decoction. The effective rate of treatment, renal function [urea nitrogen (BUN), 24 h proteinuria, creatinine (Scr), glomerular filtration rate (eGFR), urinary albumin excretion rate (UAER)], edema degree (body mass, abdominal circumference, urine volume, nocturia frequency) and TCM syndrome score were compared between the two groups. Results The total effective rate of treatment in the study group was higher than that in the control group (P<0.05). The levels of UAER, 24 h proteinuria, Scr and BUN in the study group were lower than those in the control group (P<0.05). The eGFR level in the study group was higher than that in the control group (P<0.05). The body mass, waist circumference and frequency of nocturia in the study group were lower than those in the control group (P<0.05). The urine volume of the study group was higher than that of the control group (P<0.05). The TCM symptom scores of the study group were lower than those of the control group (P<0.05). Conclusion Modified Jingui Shenqi decoction is effective in the treatment of diabetic nephropathy with spleen and kidney yang deficiency type, which can improve the renal function of patients, reduce the degree of edema and TCM syndrome score, and is worthy of clinical application.

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更新日期/Last Update: 1900-01-01