[1]柳 伟,刘莎莎.桑芩止咳汤联合定喘汤加减治疗慢性阻塞性肺疾病的临床效果及对肺功能的影响[J].医学信息,2025,38(13):146-149.[doi:10.3969/j.issn.1006-1959.2025.13.029]
　LIU Wei,LIU Shasha.Clinical Effect of Sangqin Zhike Decoction Combined with Modified Dingchuan Decoction in the Treatment of Chronic Obstructive Pulmonary Disease and its Effect on Lung Function[J].Journal of Medical Information,2025,38(13):146-149.[doi:10.3969/j.issn.1006-1959.2025.13.029]
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桑芩止咳汤联合定喘汤加减治疗慢性阻塞性肺疾病的临床效果及对肺功能的影响()

医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
38卷
期数:
2025年13期
页码:
146-149
栏目:
论著
出版日期:
2025-07-01

文章信息/Info

Title:
Clinical Effect of Sangqin Zhike Decoction Combined with Modified Dingchuan Decoction in the Treatment of Chronic Obstructive Pulmonary Disease and its Effect on Lung Function
文章编号:
1006-1959（2025）13-0146-04
作者:
柳 伟1; 刘莎莎2
1.汉阴县中医医院药剂科，陕西 汉阴 725100；2.西安市高陵区中医医院药剂科，陕西 西安 710200
Author(s):
LIU Wei1;  LIU Shasha2
1.Department of Pharmacy, Hanyin County Hospital of Traditional Chinese Medicine, Hanyin 725100, Shaanxi, China;2.Department of Pharmacy, Gaoling District Hospital of Traditional Chinese Medicine, Xi’an 710200, Shaanxi, China
关键词:
桑芩止咳汤; 定喘汤; 慢性阻塞性肺疾病; 肺功能
Keywords:
Sangqin Zhike decoction;  Dingchuan decoction;  Chronic obstructive pulmonary disease;  Pulmonary function
分类号:
R259
DOI:
10.3969/j.issn.1006-1959.2025.13.029
文献标志码:
A
摘要:
目的 研究桑芩止咳汤联合定喘汤加减治疗慢性阻塞性肺疾病的临床效果及对肺功能的影响。方法 选取2023年5月-2024年5月汉阴县中医医院诊治的78例慢性阻塞性肺疾病患者为研究对象，采用随机数字表法分为对照组和研究组，各组39例。对照组采用常规西药治疗，研究组在对照组基础上给予桑芩止咳汤+定喘汤加减治疗，比较两组肺功能指标、临床治疗效果、中医证候积分、呼吸功能指标、不良反应发生率。结果 与对照组比较，研究组治疗后FVC、FEV1、FEV1/FVC更高（P＜0.05）；与对照组治疗总有效率的84.62%比较，研究组治疗总有效率更高，达97.44%（P＜0.05）；与对照组比较，研究组治疗后咳嗽、胸闷、气促、喘息积分更低（P＜0.05）；与对照组比较，研究组治疗后PaO2更高，PaCO2更低（P＜0.05）；研究组不良反应发生率（5.13%）与对照组（7.69%）比较，差异无统计学意义（P＞0.05）。结论 桑芩止咳汤联合定喘汤加减治疗慢性阻塞性肺疾病的效果理想，可减轻中医证候，改善呼吸和肺功能，且不会增加不良反应。
Abstract:
Objective To study the clinical effect of Sangqin Zhike decoction combined with modified Dingchuan decoction in the treatment of chronic obstructive pulmonary disease and its effect on lung function. Methods A total of 78 patients with chronic obstructive pulmonary disease diagnosed and treated in Hanyin County Hospital of Traditional Chinese Medicine from May 2023 to May 2024 were selected as the research objects. By using the random number table method, patients were divided into control group and study group, 39 patients per group. The control group was treated with conventional western medicine. The study group was treated with Sangqin Zhike decoction+modified Dingchuan decoction on the basis of the control group. The lung function index, clinical treatment effect, TCM syndrome score, respiratory function index and incidence of adverse reactions were compared between the two groups. Results Compared with the control group, FVC, FEV1 and FEV1/FVC were higher in the study group after treatment (P<0.05). Compared with 84.62% of the total effective rate of the control group, the total effective rate of the study group was higher, reaching 97.44% (P<0.05). Compared with the control group, the scores of cough, chest tightness, shortness of breath and wheezing in the study group were lower after treatment (P<0.05). Compared with the control group, PaO2 was higher and PaCO2 was lower in the study group after treatment (P<0.05). There was no significant difference in the incidence of adverse reactions between the study group (5.13%) and the control group (7.69%) (P>0.05). Conclusion Sangqin Zhike decoction combined with modified Dingchuan decoction is effective in the treatment of chronic obstructive pulmonary disease, which can reduce TCM syndromes, improve respiratory and pulmonary function, and will not increase adverse reactions.

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更新日期/Last Update: 1900-01-01