[1]许小桃.康复新液联合注射用奥美拉唑钠治疗消化性溃疡出血的临床效果[J].医学信息,2025,38(19):116-120.[doi:10.3969/j.issn.1006-1959.2025.19.024]
　XU Xiaotao.Clinical Effect of Kangfuxin Liquid Combined with Omeprazole Sodium for Injectionin the Treatment of Peptic Ulcer Bleeding[J].Journal of Medical Information,2025,38(19):116-120.[doi:10.3969/j.issn.1006-1959.2025.19.024]
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康复新液联合注射用奥美拉唑钠治疗消化性溃疡出血的临床效果()

医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
38卷
期数:
2025年19期
页码:
116-120
栏目:
论著
出版日期:
2025-10-01

文章信息/Info

Title:
Clinical Effect of Kangfuxin Liquid Combined with Omeprazole Sodium for Injectionin the Treatment of Peptic Ulcer Bleeding
文章编号:
1006-1959（2025）19-0116-05
作者:
许小桃
赣州市赣县区中医院消化内科，江西 赣州 341100
Author(s):
XU Xiaotao
Department of Gastroenterology, Ganxian District Hospital of Traditional Chinese Medicine, Ganzhou 341100, Jiangxi, China
关键词:
康复新液; 注射用奥美拉唑钠; 消化性溃疡出血; D-D; PT
Keywords:
Kangfuxin liquid;  Omeprazole sodium for injection;  Peptic ulcer bleeding;  D-D;  PT
分类号:
R573.1
DOI:
10.3969/j.issn.1006-1959.2025.19.024
文献标志码:
A
摘要:
目的 研究康复新液联合注射用奥美拉唑钠治疗消化性溃疡出血的临床效果及对血清凝血酶原时间（PT）、D–二聚体（D-D）水平的影响。方法 选取2021年8月-2024年6月赣州市赣县区中医院收治的消化性溃疡出血患者60例作为研究对象，采用随机数字表法将患者分为对照组和研究组，每组30例。对照组应用康复新液治疗，研究组在对照组患者的基础上给予注射用奥美拉唑钠治疗，比较两组临床疗效、血常规指标水平[红细胞计数（RBC）、血红蛋白（Hb）、白细胞（WBC）、血小板（PLT）]、凝血功能指标水平（PT、D-D）、不良反应（头疼、恶心呕吐、便秘）发生率。结果 研究组治疗总有效率（96.67%）高于对照组（73.33%）（P＜0.05）；治疗后，研究组WBC水平均低于对照组，而RBC、PLT、Hb水平均高于对照组（P＜0.05）；研究组凝血功能指标水平（PT、D-D）均低于对照组（P＜0.05）；研究组不良反应发生率（3.33%）低于对照组（20.00%）（P＜0.05）。结论 康复新液联合注射用奥美拉唑钠治疗消化性溃疡出血的临床效果确切，可以有效促进创面修复，改善凝血功能，且不会增加不良反应的发生风险，值得临床应用。
Abstract:
Objective To study the clinical effect of Kangfuxin liquid combined with omeprazole sodium for injection in the treatment of peptic ulcer bleeding and its effect on serum prothrombin time (PT) and D-dimer (D-D) levels. Methods A total of 60 patients with peptic ulcer bleeding admitted to Ganxian District Hospital of Traditional Chinese Medicine of Ganzhou City from August 2021 to June 2024 were selected as the research objects. The patients were divided into control group and study group by random number table method, with 30 patients in each group. The control group was treated with Kangfuxin Liquid, and the study group was treated with omeprazole sodium for injection on the basis of the control group. The clinical efficacy, blood routine index levels [red blood cell count (RBC), hemoglobin (Hb), white blood cell (WBC), platelet (PLT)], coagulation function index levels (PT, D-D), and incidence of adverse reactions (headache, nausea and vomiting, constipation) were compared between the two groups. Results The total effective rate of treatment in the study group (96.67%) was higher than that in the control group (73.33%) (P<0.05). After treatment, the levels of WBC in the study group were lower than those in the control group, while the levels of RBC, PLT and Hb were higher than those in the control group (P<0.05). The levels of coagulation function indexes (PT, D-D) in the study group were lower than those in the control group (P<0.05). The incidence of adverse reactions in the study group (3.33%) was lower than that in the control group (20.00%) (P<0.05). Conclusion Kangfuxin liquid combined with omeprazole sodium for injection has a definite clinical effect in the treatment of peptic ulcer bleeding, which can effectively promote wound repair, improve coagulation function, and will not increase the risk of adverse reactions. It is worthy of clinical application.

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更新日期/Last Update: 1900-01-01