[1]吴毅巧,王 睿,徐 芳,等.中医营养学视角下食物性与味对老年人轻度认知功能障碍影响的病例对照研究[J].医学信息,2026,39(04):166-169.[doi:10.3969/j.issn.1006-1959.2026.04.031]
　WU Yiqiao,WANG Rui,XU Fang,et al.A Case-control Study on the Effects of Food Properties and Taste on Mild Cognitive Impairmentin the Elderly from the Perspective of Traditional Chinese Medicine Nutrition[J].Journal of Medical Information,2026,39(04):166-169.[doi:10.3969/j.issn.1006-1959.2026.04.031]
点击复制

中医营养学视角下食物性与味对老年人轻度认知功能障碍影响的病例对照研究()

医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
39卷
期数:
2026年04期
页码:
166-169
栏目:
照护实践信息
出版日期:
2026-02-15

文章信息/Info

Title:
A Case-control Study on the Effects of Food Properties and Taste on Mild Cognitive Impairmentin the Elderly from the Perspective of Traditional Chinese Medicine Nutrition
文章编号:
1006-1959（2026）04-0166-04
作者:
吴毅巧1; 2; 王 睿3; 徐 芳4; 庄淑涵1; 5
1.浙江中医药大学护理学院，浙江 杭州 310053；2.浙江大学医学院附属妇产科医院急诊科，浙江 杭州 311215；3.浙江工业大学化工学院，浙江 杭州 310014；4.天津中医药大学公共卫生与健康科学学院，天津 301617；5.浙江中医药大学浙江中医药文化研究院，浙江 杭州 310053
Author(s):
WU Yiqiao1; 2;  WANG Rui3;  XU Fang4;  ZHUANG Shuhan1; 5
1.School of Nursing, Zhejiang Chinese Medical University, Hangzhou 310053, Zhejiang, China; 2.Emergency Department, Women′s Hospital School of Medicine Zhejiang University, Hangzhou 310014, Zhejiang, China; 3.College of Chemical Engineering, Zhejiang University of Technology, Hangzhou 311215, Zhejiang, China; 4.School of Public Health and Health Sciences, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China;5.Zhejiang Institute of Traditional Chinese Medicine Culture, Zhejiang University of Traditional Chinese Medicine,Hangzhou 310053, Zhejiang, China
关键词:
轻度认知功能障碍; 饮食; 性
Keywords:
Mild cognitive impairment;  Diet;  Properties;  Tastes
分类号:
R247.1
DOI:
10.3969/j.issn.1006-1959.2026.04.031
文献标志码:
A
摘要:
目的 探讨老年人摄入食物的性、味与轻度认知功能障碍的关系。方法 以2020年8月-2022年10月在杭州市社区医院就诊的60周岁以上老年MCI患者216例为MCI组，按性别相同、受教育程度相同、年龄±3岁的原则匹配无MCI者432例为NMCI组，对两组进行72 h的饮食随访。使用Logistic回归分析模型分析食物的性味对MCI的影响。结果 单因素Logistic回归分析结果显示，MCI组与NMCI组寒性、热性、平性、酸味、甘味、咸味及淡味食物的摄入频次比较，差异有统计学意义（P≤0.05）；多因素Logistic回归分析结果显示，热性（OR=0.162，95%CI：0.030~0.878）、平性（OR=0.821，95%CI：0.711~0.947）食物的摄入频次多，是认知功能的保护因素（P≤0.05）。结论 老年人适当多进食热性食物、平性食物可以减缓MCI的发生。
Abstract:
Objective To investigate the relationship between the dietary properties, taste, and mild cognitive impairment in the elderly. Methods Totally 216 cases of MCI patients aged 60 years or older who were treated at community hospitals in Hangzhou from August 2020 to October 2022 were selected as MCI group. According to the principle of gender, education level, and age±3 years, 432 non-MCI individuals were matched as NMCI group. The two groups were followed up for 72 hours on diet. The Logistic regression analysis model was used to analyze the impact of dietary properties and taste on MCI. Results The univariate Logistic regression analysis showed that there were statistical differences in the frequency of cold, hot, neutral, sour, sweet, salty, and bland food intake between the MCI group and the NMCI group (P≤0.05). The multivariate Logistic regression analysis showed that the frequency of hot (OR=0.162, 95%CI: 0.030-0.878) and neutral (OR=0.821, 95%CI:0.711-0.947) food intake was significantly higher, which was a protective factor for cognitive function (P≤0.05). Conclusion Elderly people should eat more hot and neutral food to slow down the development of MCI.

参考文献/References:

[1]Buzi G,Fornari C,Perinelli A,et al.Functional connectivity changes in mild cognitive impairment: A meta-analysis of M/EEG studies[J].Clin Neurophysiol,2023,25(156):183-195. [2]程静.阿尔兹海默病和轻度认知障碍流行病学及早期血液生物标志物的研究[D].武汉:武汉科技大学,2018.[3]徐俊,石汉平.阿尔茨海默病脑健康营养干预专家共识[J].中国科学:生命科学,2021,51(12):1762-1788.[4]肖德强,徐斌,鲁力,等.食物营养成分与中医药膳性、味、归经的关联性初探[J].应用预防医学,2017,23(1):27-30.[5]中国痴呆与认知障碍诊治指南写作组,中国医师协会神经内科医师分会认知障碍疾病专业委员会.2018中国痴呆与认知障碍诊治指南(五):轻度认知障碍的诊断与治疗[J].中华医学杂志,2018,98(17):1294-1301.[6]贾荣浩,魏国辉,赵文华,等.基于K-近邻算法的中药化合物寒热平药性预测研究[J].中华中医药杂志,2023,38(4):1522-1525.[7]黄志辉,陈柳霖,蔡惠思,等.《神农本草经》与《中国药典》(2020年版)收载药物的五味差异比对研究[J].时珍国医国药,2024,35(5):1207-1210.[8]翟俊杰,郁露露,叶承静,等.可用于保健食品的中药性味归经总结分析[J].唐山师范学院学报,2023,45(6):70-73.[9]佚名.黄帝内经素问[M].北京:人民卫生出版社,1957:241.[10]黄玮,陈肖霖,黄宏强,等.轻度认知障碍患者中医体质分布情况及其认知功能与血清尿酸、超氧化物歧化酶的相关性研究[J].广州中医药大学学报,2022,39(3):481-484.[11]余忠海,董振华,刘吟枫,等.轻度认知功能障碍中医证素及证型与蒙特利尔认知评估量表的相关性研究[J].中国全科医学,2016,19(21):2562-2566,2571.[12]邹敏燕,宋玉磊,罗丹,等.中医体质与轻度认知障碍的相关性研究[J].中医药信息,2022,39(9):48-52.[13]张盼,吕莹,李秋露,等.扬刺百会穴结合舒缓音乐疗法治疗轻度认知功能障碍合并失眠的临床疗效[J].阿尔茨海默病及相关病杂志,2022,5(3):216-220.[14]李晚,张芳馨,赵薇薇,等.百会穴久留针法治疗卒中后认知障碍的临床观察[J].中国民间疗法,2024,32(1):52-55.[15]Li DD,Zhang W,Wang ZY,et al.Serum Copper, Zinc, and Iron Levels in Patients with Alzheimer′s Disease: A Meta-Analysis of Case-Control Studies[J].Front Aging Neurosci,2017,9:300.[16]章涵.176种常用食物寒热属性与六类营养素含量相关性的多元分析[D].郑州:河南中医学院,2006.[17]唐容川著,金香兰校注.血证论[M].北京:中国中医药出版社,1996:157.[18]孙冰.平性药药性理论及其应用规律研究[D].济南:山东中医药大学,2010.[19]冯敏,郏自明,万鸣,等.茯苓改善小鼠学习记忆功能作用的研究[J].食品研究与开发,2021,42(19):13-18.[20]张锡纯著,袁林,黎周校注.医学衷中参西录(中药篇)[M].郑州:河南科学技术出版社,2017:77.

相似文献/References:

[1]刘 波,罗文静,张 翼,等.血清脂联素水平与轻度认知功能障碍的相关性研究[J].医学信息,2018,31(10):7.[doi:10.3969/j.issn.1006-1959.2018.10.003]
　LIU Bo,LUO Wen-jing,ZHANG Yi,et al.Correlation between Serum Adiponectin Level and Mild Cognitive Impairment[J].Journal of Medical Information,2018,31(04):7.[doi:10.3969/j.issn.1006-1959.2018.10.003]
[2]赖 超,成官迅.rs-fMRI、DTI及1H-MRS在阿尔茨海默病中的应用进展[J].医学信息,2018,31(13):41.[doi:10.3969/j.issn.1006-1959.2018.13.013]
　LAI Chao,CHENG Guan-xun.Application of rs-fMRI、DTI and 1H-MRS in Alzheimer’s Disease[J].Journal of Medical Information,2018,31(04):41.[doi:10.3969/j.issn.1006-1959.2018.13.013]
[3]李松波,童 赟,陈裕美,等.品管圈活动在提高慢性肾功能不全患者个体化饮食执行率中的应用[J].医学信息,2019,32(06):187.[doi:10.3969/j.issn.1006-1959.2019.06.062]
　LI Song-bo,TONG Yun,CHEN Yu-mei,et al.Application of Quality Control Circle Activities in Improving the Individualized Diet Implementation Rate of Patients with Chronic Renal Insufficiency[J].Journal of Medical Information,2019,32(04):187.[doi:10.3969/j.issn.1006-1959.2019.06.062]
[4]高 敏,高 波,寇忠平,等.神木市儿童BMI情况调查及影响因素分析[J].医学信息,2025,38(21):33.[doi:10.3969/j.issn.1006-1959.2025.21.006]
　GAO Min,GAO Bo,KOU Zhongping,et al.Investigation on BMI of Children in Shenmu City and its Influencing Factors[J].Journal of Medical Information,2025,38(04):33.[doi:10.3969/j.issn.1006-1959.2025.21.006]

更新日期/Last Update: 1900-01-01