[1]李庆华.复可托治疗小儿反复肺炎支原体感染的疗效及对 免疫功能和肺功能的影响[J].医学信息,2018,31(16):128-130.[doi:10.3969/j.issn.1006-1959.2018.16.040]
 LI Qing-hua.Therapeutic Effect of Fuketuo on Recurrent Mycoplasma Pneumoniae Infection in Children and its Influence on Immune and Pulmonary Function[J].Journal of Medical Information,2018,31(16):128-130.[doi:10.3969/j.issn.1006-1959.2018.16.040]
点击复制

复可托治疗小儿反复肺炎支原体感染的疗效及对 免疫功能和肺功能的影响()
分享到:

医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
31卷
期数:
2018年16期
页码:
128-130
栏目:
药物与临床
出版日期:
2018-08-15

文章信息/Info

Title:
Therapeutic Effect of Fuketuo on Recurrent Mycoplasma Pneumoniae Infection in Children and its Influence on Immune and Pulmonary Function
文章编号:
1006-1959(2018)16-0128-03
作者:
李庆华
武汉市黄陂区人民医院儿科,湖北 武汉 430300
Author(s):
LI Qing-hua
Department of Pediatrics,People's Hospital of Huangpi District,Wuhan 430300,Hubei,China
关键词:
复可托小儿支原体肺炎免疫功能肺功能
Keywords:
Key words:FuketuoMycoplasma pneumonia in childrenImmune functionPulmonary function
分类号:
R725.6
DOI:
10.3969/j.issn.1006-1959.2018.16.040
文献标志码:
A
摘要:
目的 探讨复可托治疗小儿反复肺炎支原体感染的疗效及对免疫功能和肺功能的影响。方法 选取我院2015年1月~2017年1月收治的88例反复MP感染患儿为研究对象,采用随机数字表法分为两组,各44例。对照组患儿给予常规治疗,观察组在对照组基础上口服复可托,对比两组患儿临床疗效、免疫指标、肺功能指标。结果 观察组总有效率为97.73%,高于对照组的81.82%,差异有统计学意义(P<0.05)。观察组患儿IgA、IgM、IgG、CD4+、CD8+、CD4+/CD8+等免疫指标优于对照组,差异有统计学意义(P<0.05)。观察组患儿肺功能指标FVC、FEV1、PEF、FEF25、FEF50、FEF75均优于对照组,差异具有统计学意义(P<0.05)。结论 复可托治疗小儿反复MP感染临床疗效显著,可有效改善免疫功能和肺功能。
Abstract:
Abstract:Objective To investigate the effect of Fuketuo on the immune function and pulmonary function in children with recurrent mycoplasma pneumoniae infection.Methods 88 children with repeated MP infection from January 2015 to January 2017 were selected and randomly divided into two groups,44 cases in each group.The children in the control group were given routine treatment, and the observation group was treated with Fukotuo on the basis of the control group.The clinical efficacy,immune index and pulmonary function index were compared between the two groups.Results The total effective rate of the observation group was 97.73%,which was higher than 81.82% of the control group,the difference was statistically significant(P<0.05).IgA,IgM,IgG,CD4+, CD8+,CD4+/CD8+and other immune indexes in the observation group were superior to the control group,the difference was statistically significant(P<0.05).The lung function indexes FVC,FEV1,PEF,FEF25,FEF50 and FEF75 in the observation group were superior to the control group,the difference was statistically significant(P<0.05).Conclusion The clinical efficacy of Fuketuo in the treatment of recurrent MP infection in children is significant,which can effectively improve immune function and lung function.

参考文献/References:

[1]沈洁,卢燕.小儿肺炎支原体肺炎的临床诊治研究进展[J].中国基层医药,2013,20(3):441-442.
[2]屈锐.孟鲁司特联合复可托对哮喘患儿血清TGF-β1、MCP-1及SDF-1水平的影响[J].临床医学研究与实践,2017,2(31):90-91.
[3]沈小飞,周艾,黄群.复可托(脾氨肽口服冻干粉)对儿童扁桃体摘除术后免疫功能疗效分析[J].临床耳鼻咽喉头颈外科杂志,2017,31(21):1690-1692.
[4]李晓佳,路璐,杨宁,等.复可托对恶性肿瘤患者免疫功能、生活质量影响的临床观察[J].现代生物医学进展,2017,17(29):5705-5707,5689.
[5]孙祖红,倪志峰.复可托联合蒲地蓝治疗手足口病的疗效观察[J].淮海医药,2016,34(02):210-211.
[6]牛锦龙.复可托治疗儿童哮喘合并反复呼吸道感染的疗效观察[J].西部医学,2015,27(01):45-46,49.
[7]余晓芬,陈进,陈新伟.经肺俞穴超声导入阿奇霉素治疗小儿支原体感染的安全性及临床疗效[J].中国地方病防治杂志,2017(1):83.
[8]李兰芳,万德煌.顺尔宁联合复可托治疗儿童支气管哮喘疗效观察[J].医学理论与实践,2012,25(21):2638-2639.
[9]唐庆,李少宁,詹文娟.复可托治疗小儿反复肺炎支原体感染的疗效及对免疫功能和肺功能的影响[J].广西医科大学学报,2018,35(01):33-37.

相似文献/References:

[1]梁 曼,赵俊芝.阿奇霉素序贯疗法治疗小儿支原体肺炎的疗效观察[J].医学信息,2018,31(04):7.[doi:10.3969/j.issn.1006-1959.2018.04.003]
 LIANG Man,ZHAO Jun-zhi.Effect of Azithromycin Sequential Therapy on Mycoplasma Pneumonia in Children[J].Journal of Medical Information,2018,31(16):7.[doi:10.3969/j.issn.1006-1959.2018.04.003]
[2]陈艳丽.血清CRP在小儿支原体肺炎诊治中的价值[J].医学信息,2019,32(18):181.[doi:10.3969/j.issn.1006-1959.2019.18.064]
 CHEN Yan-li.The Value of Serum CRP in the Diagnosis and Treatment of Mycoplasmal Pneumonia in Children[J].Journal of Medical Information,2019,32(16):181.[doi:10.3969/j.issn.1006-1959.2019.18.064]

更新日期/Last Update: 2018-08-15