[1]梁 曼,赵俊芝.阿奇霉素序贯疗法治疗小儿支原体肺炎的疗效观察[J].医学信息,2018,31(04):7-9.[doi:10.3969/j.issn.1006-1959.2018.04.003]
　LIANG Man,ZHAO Jun-zhi.Effect of Azithromycin Sequential Therapy on Mycoplasma Pneumonia in Children[J].Medical Information,2018,31(04):7-9.[doi:10.3969/j.issn.1006-1959.2018.04.003]
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阿奇霉素序贯疗法治疗小儿支原体肺炎的疗效观察()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
31卷
期数:
2018年04期
页码:
7-9
栏目:
出版日期:
2018-02-15

文章信息/Info

Title:
Effect of Azithromycin Sequential Therapy on Mycoplasma Pneumonia in Children
文章编号:
1006-1959（2018）04-0007-03
作者:
梁 曼; 赵俊芝
辽宁省抚顺市抚顺县人民医院儿科，辽宁 抚顺 113006
Author(s):
LIANG Man; ZHAO Jun-zhi
Department of Pediatric,Fushun People’s Hospital,Fushun 113006,Liaoning,China
关键词:
阿奇霉素序贯疗法; 小儿支原体肺炎; 安全性
Keywords:
Key words：Azithromycin sequential therapy; Mycoplasma pneumonia in children; Safety
分类号:
R725.6
DOI:
10.3969/j.issn.1006-1959.2018.04.003
文献标志码:
A
摘要:
目的 观察并研究阿奇霉素序贯疗法治疗小儿支原体肺炎的临床疗效。方法 选择2015年3月～2017 年4月我院收治的84例小儿支原体肺炎患者作为研究对象，随机分为对照组40例和观察组44例。观察组采用阿奇霉素序贯疗法,对照组采用红霉素序贯疗法,观察两组患儿临床症状及体征改善情况，并比较两组临床疗效及不良反应情况。结果 观察组小儿支原体肺炎治疗总有效率（95.45%）高于对照组（82.50%），差异有统计学意义（P＜0.05）。观察组咳嗽气促症状改善（2.54±0.69）d、肺部啰音改善（3.14±0.97）d、发热消失时间（3.45±0.67）d和住院时间（7.24±1.38）d均低于对照组（3.79±1.04）d、（4.89±1.13）d、（4.73±0.89）d、（9.68±2.04）d，差异有统计学意义（P＜0.05）。观察组不良反应发生率（11.36%）低于对照组（20.00%）, 差异有统计学意义（P＜0.05）。结论 小儿支原体肺炎采用阿奇霉素序贯疗法治疗效果可靠，可快速改善患儿临床症状、体征，且毒副作用较小，有助于缩短患儿病程，提高疗效。
Abstract:
Abstract：Objective To observe and study the clinical efficacy of azithromycin sequential therapy in the treatment of mycoplasma pneumonia in children.Methods 84 cases of mycoplasma pneumonia in our hospital from March 2015 to April 2017 were selected as the subjects,and they were randomly divided into 40 cases in the control group and 44 in the observation group.The observation group was treated with azithromycin sequential therapy,while the control group was treated with erythromycin sequential therapy.The clinical symptoms and signs improvement of the two groups were observed,and the clinical efficacy and adverse reactions of the two groups were compared.Results The total effective rate of mycoplasma pneumonia in the observation group(95.45%)was higher than that of the control group(82.50%),and the difference was statistically significant(P<0.05).In the observation group,the symptoms of cough and shortness of breath were improved(2.54±0.69)d,the lung rales were improved(3.14±0.97)d,the time of fever disappeared was(3.45±0.67)d,and the hospitalization time was(7.24±1.38)d,which was lower than that in the control group of（3.79±1.04）d,（4.89±1.13）d,（4.73±0.89）d,（9.68±2.04）d,the difference was statistically significant(P<0.05).The incidence of adverse reactions in the observation group (11.36%)was lower than that in the control group(20.00%),the difference was statistically significant(P<0.05).Conclusion Azithromycin sequential therapy for mycoplasma pneumonia in children is effective and can improve the clinical symptoms and signs of children with less side effects.It is helpful to shorten the course of disease and improve the curative effect of children with mycoplasma pneumoniae.

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更新日期/Last Update: 2018-02-15