[1]包娜娜,刘 超.太极拳对遗忘型轻度认知功能障碍患者认知功能影响的研究[J].医学信息,2019,32(02):115-117.[doi:10.3969/j.issn.1006-1959.2019.02.032]
 BAO Na-na,LIU Chao.Study on Taijiquan in Patients with Amnestic Mild Cognitive Dysfunction[J].Journal of Medical Information,2019,32(02):115-117.[doi:10.3969/j.issn.1006-1959.2019.02.032]
点击复制

太极拳对遗忘型轻度认知功能障碍患者认知功能影响的研究()
分享到:

医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
32卷
期数:
2019年02期
页码:
115-117
栏目:
临床研究
出版日期:
2019-01-15

文章信息/Info

Title:
Study on Taijiquan in Patients with Amnestic Mild Cognitive Dysfunction
文章编号:
1006-1959(2019)02-0115-03
作者:
包娜娜1刘 超2
1.川北医学院神经疾病研究所,四川 南充 637000;2.川北医学院附属医院神经内科,四川 南充 637000
Author(s):
BAO Na-na1LIU Chao2
1.Institute of Neurological Diseases,North Sichuan Medical College,Nanchong 637000,Sichuan,China;2.Department of Neurology, Affiliated Hospital of North Sichuan Medical College,Nanchong 637000,Sichuan,China
关键词:
遗忘型轻度认知功能障碍太极拳事件相关电位认知功能
Keywords:
Forgotten mild cognitive impairmentTaijiquanEvent-related potentialCognitive function
分类号:
R749.1+6
DOI:
10.3969/j.issn.1006-1959.2019.02.032
文献标志码:
A
摘要:
目的 探讨太极拳对遗忘型轻度认知功能障碍(a-MCI)患者认知功能的影响。方法 将62例a-MCI患者随机分为对照组和观察组,每组31例。对照组患者接受常规健康教育,治疗组在此基础上接受太极拳干预治疗。两组患者分别在治疗前、治疗后6个月采用简明精神状态检查量表(MMSE)、蒙特利尔认知评估量表(MoCA)以及事件相关电位P300对患者认知功能评价。结果 对照组治疗前后MMSE、MoCA评分分别比较,差异无统计学意义(P>0.05);治疗后观察组MMSE、MoCA评分分别为(25.12±4.17)分、
Abstract:
Objective To investigate the effect of Taijiquan on cognitive function in patients with amnestic mild cognitive impairment (a-MCI). Methods 62 patients with a-MCI were randomly divided into control group and observation group, with 31 cases in each group. The patients in the control group received regular health education, and the treatment group received Taijiquan intervention on this basis. Patients in the two groups were evaluated for cognitive function using the Concise Mental Status Examination Scale (MMSE), the Montreal Cognitive Assessment Scale (MoCA), and the event-related potential P300 before and 6 months after treatment. Results There were no significant differences in MMSE and MoCA scores between the control group and the control group (P>0.05). After treatment, the MMSE and MoCA scores of the observation group were (25.12±4.17) and (25.64±3.19), respectively.The scores were higher than (17.31±5.26) and (20.13±2.48) before treatment, and the MMSE and MoCA scores of the observation group were higher than those of the control group (17.91±5.66) and (19.93±2.68),the difference was statistically significant (P<0.05). There was no significant difference in P300 latency and amplitude between the control group before and after treatment(P>0.05). After treatment, the P300 latency of the observation group was shorter than before (363.12±36.97) ms vs. (407.81±31.46) ms, amplitude increased (6.64±4.59)μV vs(3.73±2.48)μV, the difference was statistically significant(P<0.05). The latency and amplitude of P300 in the observation group were better than those in the control group (403.61± 32.26) ms and (3.73 ± 2.38) μV, the difference was statistically significant (P<0.05). Conclusion Taijiquan can improve the cognitive function of patients with a-MCI and can be used as an intervention to prevent a-MCI.

参考文献/References:

[1]Ding D,Zhao Q,Guo Q,et al.Prevalence of mild cognitive impairment in an urban community in China:a cross-sectional analysis of the Shanghai Aging Study[J].Alzheimers Dement.2015,11(3):300-309.
[2]Misiak B,Leszek J,Kiejna A.Metabolic syndrome,mild cognitive impairment and Alzheimer's disease-the emerging role of systemic low-grade inflammation and adiposity[J].Brain Res Bull,2012,89(3-4):144-149.
[3]隆世宇,王晓明,罗成,等.重复经颅磁刺激对遗忘型轻度认知功能障碍患者认知功能及长程功能性连接的影响[J].中国老年学杂志,2018,38(4):785-788.
[4]Wayne PM,Walsh JN,Taylor-Piliae PE,et al.Effect of Tai Chi on cognitive performance in older adults:systematic review and meta-analysis[J].J Am Geriatr Soc,2014,62(1):25-39.
[5]Petersen RC.Mild cognitive impairment as a diagnostic entity[J].J Intern Med,2004,256(3):183-194.
[6]师仰宏,霍艳艳.高血压对阿尔茨海默病患者血浆可溶性CD40及配体水平的影响[J].川北医学院学报,2018,33(4):480-482.
[7]郁洁,王滨,洪侃,等.合并认知功能障碍的脑小血管病老年患者血同型半胱氨酸及炎症介质水平的改变及意义[J].川北医学院学报,2018,33(4):496-499.
[8]章军建,王涛.混合性认知损害--一个临床新概念[J].中华医学杂志,2016,96(45):3634-3636.
[9]温洁新.阿尔茨海默病和轻度认知障碍患者血尿生物标志物的筛选[D].河北医科大学,2014.
[10]李日臻,刘运林,王良鑫,等.脑灵汤结合太极拳对阿尔茨海默病患者康复的影响[J].现代中西医学结合杂志,2013,22(7):693-760.
[11]Li F,Harmer P,Liu Y,et al.Tai Ji Quan and global cognitive function in older adults with cognitive impairment:a pilot study[J].Arch Gerontol Geriatr,2014,58(3):434-439.
[12]Wei GX,Xu T,Fan FM,et al.Can Tai Chi reshape the brain? A brain morphometry study[J].Plos One,2013,8(4):e61038.
[13]Tao J,Chen X,Egorova N,et al.Tai Chi Chuan and Baduanjin practice modulates functional connectivity of the cognitive control network in older adults[J].Sci Rep,2017(7):41581.
[14]Sunqkarat S,Boripuntakul S,Kumfu S,et al.Tai Chi improves cognitive and plasma BDNF in older adults with mild cognitive impairment:a randomized controlled trial[J].Neurorehabil Neural Repair,2018,32(2):142-149.

更新日期/Last Update: 2019-02-15