[1]秦 帅,侯光辉,祁 冰,等.多种药物联合治疗白内障术后干眼症的临床效果观察[J].医学信息,2019,32(04):142-144.[doi:10.3969/j.issn.1006-1959.2019.04.046]
　QIN Shuai,HOU Guang-hui,QI Bing,et al.Clinical Observation of Multiple Drugs Combined with Xerophthalmia after Cataract Surgery[J].Journal of Medical Information,2019,32(04):142-144.[doi:10.3969/j.issn.1006-1959.2019.04.046]
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多种药物联合治疗白内障术后干眼症的临床效果观察()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
32卷
期数:
2019年04期
页码:
142-144
栏目:
药物与临床
出版日期:
2019-02-15

文章信息/Info

Title:
Clinical Observation of Multiple Drugs Combined with Xerophthalmia after Cataract Surgery
文章编号:
1006-1959（2019）04-0142-03
作者:
秦 帅; 侯光辉; 祁 冰; 郭 锐
（珠海市人民医院眼科，广东 珠海 519000）
Author(s):
QIN Shuai; HOU Guang-hui; QI Bing; GUO Rui
(Department of Ophthalmology,Zhuhai People's Hospital,Zhuhai 519000,Guangdong,China)
关键词:
白内障; 干眼症; 普拉洛芬; 贝复舒
Keywords:
Cataract; Xerophthalmia; Pranoprofen; Befushu
分类号:
R779.6
DOI:
10.3969/j.issn.1006-1959.2019.04.046
文献标志码:
A
摘要:
目的 探讨多种药物联合治疗白内障术后干眼症的临床疗效。方法 选取2015年5月~2018年 9 月于我院行白内障手术术后干眼患者125例，随机分为A、B、C组三组，C组患者采用玻璃酸钠滴眼液治疗，A组在C组基础上加用贝复舒滴眼液治疗，B组在C组基础上加用普拉洛芬滴眼液治疗，比较各组患者治疗前后OSDI值、BUT、SIt值、FL的变化，比较各组患者治疗前后OSDI值、BUT、SIt值、FL的变化。结果 治疗后三组患者BUT，SIt值比较，差异有统计学意义（P＜0.05）；治疗后三组OSDI值，FL比较，差异无统计学意义（P＞0.05）；B组患者治疗的总有效率（95.24%）高于A组（93.02%）及C组（87.50%），差异有统计学意义（P＜0.05）。结论 玻璃酸钠滴眼液联合普拉洛芬滴眼液、玻璃酸钠滴眼液联合贝复舒滴眼液及单纯使用玻璃酸钠滴眼液均可减轻白内障术后干眼症患者的症状，增加泪液分泌量，延长泪膜破裂时间，使角膜染色降低，但玻璃酸钠滴眼液联合普拉洛芬滴眼液的治疗方案更佳。
Abstract:
Objective To investigate the clinical efficacy of multiple drugs in the treatment of xerophthalmiaafter cataract surgery. Methods A total of 125 patients with xerophthalmia who underwent cataract surgery in our hospital from May 2015 to September 2018 were randomly divided into three groups: group A, group B and group C. Patients in group C were treated with sodium hyaluronate eye drops. Group A was treated with Beifushu eye drops on the basis of group C. Group B was treated with pranoprofen eye drops on the basis of group C.The changes of OSDI, BUT, SIt and FL before and after treatment were compared between the groups. Results After treatment, the BUT and SIt values of the three groups were significantly different (P<0.05). There were no significant differences in the OSDI values and FL between the three groups after treatment (P>0.05). The effective rate (95.24%) was higher than that of group A (93.02%) and group C (87.50%),the difference was statistically significant (P<0.05). Conclusion Sodium hyaluronate eye drops combined with pranoprofen eye drops, sodium hyaluronate eye drops combined with Beifushu eye drops and sodium hyaluronate eye drops alone can alleviate the symptoms of xerophthalmia patients after cataract surgery. Increase the amount of tear secretion, prolong the tear film rupture time, and reduce the cornea staining, but the treatment plan of sodium hyaluronate eye drops combined with pranoprofen eye drops is better.

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更新日期/Last Update: 2019-03-07