[1]陈宽玉,孔 骞,黄玉桃.首发缓解期精神分裂症患者日常生活模式的调查[J].医学信息,2019,32(04):182-185.[doi:10.3969/j.issn.1006-1959.2019.04.061]
　CHEN Kuan-yu,KONG Qian,HUANG Yu-tao.Investigation on the Daily Life Pattern of Patients with Schizophrenia in the First Remission Period[J].Journal of Medical Information,2019,32(04):182-185.[doi:10.3969/j.issn.1006-1959.2019.04.061]
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首发缓解期精神分裂症患者日常生活模式的调查()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
32卷
期数:
2019年04期
页码:
182-185
栏目:
护理研究
出版日期:
2019-02-15

文章信息/Info

Title:
Investigation on the Daily Life Pattern of Patients with Schizophrenia in the First Remission Period
文章编号:
1006-1959（2019）04-0182-04
作者:
陈宽玉1; 2; 孔 骞1; 黄玉桃1; 3
（1.湖州师范学院，浙江 湖州 313000；2.江苏省扬州五台山医院，江苏 扬州 225003；3.浙江省湖州市中心医院，浙江 湖州 313000）
Author(s):
CHEN Kuan-yu1; 2; KONG Qian1; HUANG Yu-tao1; 3
(1.Huzhou University,Huzhou 313000,Zhejiang,China;2.Wutaishan Hospital of Yangzhou,Yangzhou 225003,Jiangsu,China;3.Huzhou Central Hospital of Zhejiang Province,Huzhou 313000,Zhejiang,China)
关键词:
精神分裂症; 缓解期; 日常生活模式
Keywords:
Schizophrenia; Remission; Daily life pattern
分类号:
R749.3
DOI:
10.3969/j.issn.1006-1959.2019.04.061
文献标志码:
A
摘要:
目的 通过探讨首发缓解期精神分裂症患者的日常生活模式，分析主动活动在促进患者认知水平、社会功能上的积极作用，旨为医护人员在临床护理工作中提供参考。方法 选取2015年8月~2017年8月江苏省扬州五台山医院门诊或住院的首发缓解期精神分裂症患者68例作为患者组，选取同期该院职工及其家属50例作为对照组。采用日常生活模式量表（DRM）评定日常生活行为，连线测验（TMT）评估认知功能，社会功能缺陷量表（SDSS）评估患者的社会功能，阳性和阴性症状量表（PANSS）对患者精神症状进行评定。结果 患者组从事工作的人数少于对照组，差异有统计学意义（P＜0.05）。患者组PANSS阳性症状得分为（9.54±4.73）分，阴性症状分数为（12.49±5.47）分，一般精神病理分数为（18.22±5.21）分，总分为（40.25±4.36）分；氯丙嗪当量为（396.53±169.62）mg/d，SDSS评分为（6.57±1.67）分。患者组DRM主动活动次数和时间均少于对照组，差异具有统计学意义（P＜0.05）。患者组花费在主动活动上的时间与社会功能存在相关性（r=-0.348，P＜0.05），并且患者主动活动的次数和认知功能TMT-A（r=-0.302，P＜0.05）和TMT-B（r=-0.251，P＜0.05）密切相关。结论 首发缓解期精神分裂症患者主动活动次数和时间减少，并且社会功能越差的患者消耗在主动活动上的时间越少。
Abstract:
Objective To explore the positive effects of active activities on the cognitive level and social function of patients with schizophrenia in the first remission period, and to provide reference for medical staff in clinical nursing work. Methods From August 2015 to August 2017, 68 patients with first-time remission schizophrenia in the outpatient or inpatient hospital of Wutaishan Hospital in Yangzhou, Jiangsu Province were selected as the patient group. 50 patients in the same period and their family members were selected as the control group. Daily life patterns (DRM) were used to assess behaviors of daily life,the Connectivity Test (TMT) assesses cognitive function, the Social Function Deficit Scale (SDSS) assesses the patient's social function, and the Positive and Negative Symptom Scale (PANSS) assesses the patient's psychiatric symptoms. Results The number of patients in the patient group was lower than that in the control group, the difference was statistically significant (P<0.05). The PANSS positive symptom score in the patient group was (9.54±4.73), the negative symptom score was (12.49±5.47), the general psychopathological score was (18.22±5.21), and the total score was (40.25±4.36). The chlorpromazine equivalent was (396.53±169.62) mg/d, and the SDSS score was (6.57±1.67) points. The number and duration of DRM active activities in the patient group were lower than those in the control group,the difference was statistically significant (P<0.05). There was a correlation between the time spent on active activities and social function in the patient group (r=-0.348, P<0.05), and the number of active activities and cognitive function TMT-A (r=-0.302, P<0.05) and TMT-B (r=-0.251, P<0.05) is closely related. Conclusion The number and duration of active activities in patients with schizophrenia during the first remission period are reduced, and the patients with worse social function spend less time on active activities.

参考文献/References:


[1]Mier D,Kirsch P.Social-Cognitive Deficits in Schizophrenia[J].Curr Top Behav Neurosci,2017(30):397-409.
[2]Marchesi C,Affaticati A,Monici A,et al.Decrease of functioning in remitted and non-remitted patients 16 years after a first-episode schizophrenia[J].Journal of Nervous & Mental Disease,2015,203(6):406.
[3]Revsbech R,Mortensen EL,Nordgaard J,et al.Exploring social cognition in schizophrenia[J].Eur Arch Psychiatry Clin Neurosci,2017,267(7):611-619.
[4]Fervaha G,Agid O,McDonald K,et al.Daily activity patterns in remitted first-episode schizophrenia[J].Compr Psychiatry,2014,55(5):1182-1187.
[5]金珠玛,倪苏琳,任方芳,等.缓解期精神分裂症患者认知功能的研究[J].中外医学研究,2011,09(34):13-15.
[6]刘鹏,陈宽玉,唐小伟,等.首发精神分裂症患者缓解期神经认知功能和社会认知功能的研究[J].临床精神医学杂志,2018,28(1):45-47.
[7]周亚楠,翟金国,陈敏.首发精神分裂症精神病未治期对认知功能和社会功能的影响[J].中国神经精神疾病杂志,2018,44(1):41-46.
[8]American Psychiatric Association.Diagnostic and statistical manual of mental disorders: DSM-5?(5th ed.)[M].US:American Psychiatric Association Publishing,2013.
[9]Leucht S,Davis JM,Engel RR,et al.Definitions of response and remission in schizophrenia: recommendations for their use and their presentation[J].Acta Psychiatrica Scandinavica Supplementum,2011,124(1):7-14.
[10]Andreasen NC,Jr CW,Kane JM,et al.Remission in schizophrenia: proposed criteria and rationale for consensus[J].American Journal of Psychiatry,2005,162(3):441-449.
[11]Diener E,Tay L.Review of the Day Reconstruction Method (DRM)[J].Social Indicators Research,2014,116(1):255-267.
[12]Miret M,Caballero FF,Mathur A,et al.Validation of a Measure of Subjective Well-Being: An Abbreviated Version of the Day Reconstruction Method[J].PLoS One,2012,7(8):4154-4160.
[13]Wu JQ,Chen da C,Tan YL,et al.Cognitive impairments in first-episode drug-naive and chronic medicated schizophrenia: MATRICS consensus cognitive battery in a Chinese Han population[J].Psychiatry Res,2016,238(2):196-202.
[14]欧玉芬,何红波,宁玉萍,等.不同病程的稳定期精神分裂症患者认知功能比较[J].四川精神卫生,2017,30(6):524-527.
[15]Mehta UM,Thirthalli J,Basavaraju R,et al.Reduced mirror neuron activity in schizophrenia and its association with theory of mind deficits: evidence from a transcranial magnetic stimulation study[J].Schizophrenia Bulletin,2014,40(5):1083-1094.
[16]肖垚南,陈丁玲,陈梓朗,等.稳定期精神分裂症患者精神症状、认知功能与社会功能的相关性[J].四川精神卫生,2017,30(1):54-57.
[17]Harness ET,Astorino TA,Knoblach SM,et al.Change in neuroplasticity-related proteins in response to acute activity-based therapy in persons with spinal cord injury[J].Topics in Spinal Cord Injury Rehabilitation,2014,20(2):147-157.
[18]Hare SM,Law AS,Ford JM,et al.Disrupted network cross talk, hippocampal dysfunction and hallucinations in schizophrenia[J].Schizophrenia Research,2018,199(3):226-234.
[19]Lieberman JA,Girgis RR,Brucato G,et al.Hippocampal dysfunction in the pathophysiology of schizophrenia: a selective review and hypothesis for early detection and intervention[J].Molecular Psychiatry,2018,23(8):1764-1772.
[20]Antoniades M,Schoelera T,Radua J,et al.Verbal learning and hippocampal dysfunction in schizophrenia: Ameta-analysis[J].Neuroscience & Biobehavioral Reviews,2018,86(12):166-175.

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更新日期/Last Update: 2019-03-07