[1]陈 欢,李秀惠.急、慢性乙型肝炎及乙肝肝硬化患者 肝功能及血脂水平分析[J].医学信息,2019,32(12):67-69.[doi:10.3969/j.issn.1006-1959.2019.12.021]
　CHEN Huan,LI Xiu-hui.Analysis of Liver Function and Blood Lipid Levels in Patients with Acute, Chronic Hepatitis B and Hepatitis B Cirrhosis[J].Journal of Medical Information,2019,32(12):67-69.[doi:10.3969/j.issn.1006-1959.2019.12.021]
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急、慢性乙型肝炎及乙肝肝硬化患者 肝功能及血脂水平分析()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
32卷
期数:
2019年12期
页码:
67-69
栏目:
论著
出版日期:
2019-06-15

文章信息/Info

Title:
Analysis of Liver Function and Blood Lipid Levels in Patients with Acute, Chronic Hepatitis B and Hepatitis B Cirrhosis
文章编号:
1006-1959（2019）12-0067-03
作者:
陈 欢; 李秀惠
首都医科大学附属北京佑安医院中西医结合肝病科，北京 100069
Author(s):
CHEN Huan;  LI Xiu-hui
Department of Integrated Traditional Chinese Medicine and Western Medicine, Beijing Youan Hospital,Capital Medical University,Beijing 100069
关键词:
急性乙型肝炎; 慢性乙型肝炎; 乙肝肝硬化; 血脂水平
Keywords:
Key words：Acute hepatitis B; Chronic hepatitis B; Hepatitis B cirrhosis; Blood lipid levels
分类号:
R512.6+2
DOI:
10.3969/j.issn.1006-1959.2019.12.021
文献标志码:
A
摘要:
目的 分析急、慢性乙型肝炎、乙肝肝硬化患者血脂水平及患者血脂水平的变化情况。方法 选择2015年1月~2018年12月我院收治的急性乙型肝炎患者40例作为急性乙型肝炎组，慢性乙型肝炎患者44例作为慢性乙型肝炎组、乙肝肝硬化患者35例作为乙肝肝硬化组，采用回顾性调查方法比较急、慢性乙型肝炎及乙肝肝硬化患者肝功能及血脂水平。结果 急性乙型肝炎组与慢性乙型肝炎组在ALT、AST、TBIL、DBIL比较，差异有统计学意义（P＜0.05）；急性乙型肝炎组与乙肝肝硬化组在ALT、AST、ALB、TBIL、DBIL、PT、PTA、INR比较，差异有统计学意义（P＜0.05）；慢性乙型肝炎组与乙肝肝硬化组在ALT、AST、ALB、PT、PTA、INR比较，差异有统计学意义（P＜0.05）。急性乙型肝炎组TG高于慢性乙型肝炎组与乙肝肝硬化组，差异有统计学意义（P＜0.05）；慢性乙型肝炎组CHO水平高于急性乙型肝炎组与乙肝肝硬化组，差异有统计学意义（P＜0.05）；急性乙型肝炎组、慢性乙型肝炎组、乙肝肝硬化组在HDL-C、LDL-C间比较，差异无统计学意义（P＞0.05）。结论 急、慢性乙型肝炎及乙肝肝硬化患者血脂水平逐渐降低，以TG下降为主，与肝功能损伤有关，是评估乙型肝炎病程进展的一个重要指标。
Abstract:
Abstract：Objective To analysis the blood lipid levels of patients with acute and chronic hepatitis B and hepatitis B cirrhosis, as well as changes in blood lipid levels.Methods From January 2015 to December 2018, 40 patients with acute hepatitis B as acute hepatitis B group, 44 patients with chronic hepatitis B as chronic hepatitis B group, and 35 patients with hepatitis B cirrhosis as hepatitis B cirrhosis group were selected. The retrospective investigation method was used to compare the liver function and blood lipid level of patients.Results There was statistically significant difference between acute hepatitis B and chronic hepatitis B in ALT、AST、TBiL、DBiL (P＜0.05); there was statistically significant difference between acute hepatitis B and hepatitis B cirrhosis in ALT、AST、ALB、TBiL、DBiL、PT、PTA、INR (P＜0.05); there was statistically significant difference between chronic hepatitis B and hepatitis B cirrhosis in ALT、AST、ALB、PT、PTA、INR (P＜0.05). The TG was higher in acute hepatitis B than that in chronic hepatitis B and hepatitis B cirrhosis, the difference was statistically significant (P＜0.05); the CHO was higher in chronic hepatitis B than that in acute hepatitis B and hepatitis B cirrhosis, the difference was statistically significant (P＜0.05); there was no statistically significant difference among three groups in HDL-C and LDL-C (P＞0.05).Conclusion The blood lipid levels of patients with acute, chronic hepatitis B and hepatitis B cirrhosis gradually decreased, mainly TG. The changes of blood lipids have related to liver function damage, is an important indicator for assessing the progress of hepatitis B disease.

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更新日期/Last Update: 2019-06-15