[1]王 丽.金水宝片对原发性肾病综合征患者血液流变学的影响[J].医学信息,2019,32(18):156-157.[doi:10.3969/j.issn.1006-1959.2019.18.054]
　WANG Li.Effect of Jinshuibao Tablet on Hemorheology in Patients with Primary Nephrotic Syndrome[J].Journal of Medical Information,2019,32(18):156-157.[doi:10.3969/j.issn.1006-1959.2019.18.054]
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金水宝片对原发性肾病综合征患者血液流变学的影响()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
32卷
期数:
2019年18期
页码:
156-157
栏目:
药物与临床
出版日期:
2019-09-15

文章信息/Info

Title:
Effect of Jinshuibao Tablet on Hemorheology in Patients with Primary Nephrotic Syndrome
文章编号:
1006-1959（2019）18-0156-02
作者:
王 丽
佳木斯市中医院肾内科，黑龙江 佳木斯 154002
Author(s):
WANG Li
Department of Nephrology,Jiamusi Traditional Chinese Medicine Hospital,Jiamusi 154002, Heilongjiang,China
关键词:
金水宝片; 原发性肾病综合征; 血液流变学; 肾功能
Keywords:
Key words：Jinshuibao tablet; Primary nephrotic syndrome; Hemorheology; Renal function
分类号:
R692
DOI:
10.3969/j.issn.1006-1959.2019.18.054
文献标志码:
A
摘要:
目的 探讨金水宝片对原发性肾病综合征患者血液流变学的影响。方法 选取2018年1月~2019年2月我院收治的原发性肾病综合征患者患者78例，按照随机数字表法分为对照组和研究组，各39例。两组均给予常规治疗，对照组给予泼尼松龙片治疗，研究组在对照组基础上给予金水宝片治疗，比较两组血液流变学及肾功能指标变化。结果 研究组全血粘度低切、全血粘度高切、血浆粘度及红细胞压积均低于对照组[（8.42±2.03）mPa·s vs（10.59±2.14）mPa·s]、[（3.94±1.22）mPa·s vs（6.36±1.30）mPa·s]、[（1.32±0.21）mPa·s vs（1.80±0.34）mPa·s]、[（42.10±2.53）% vs（46.18±2.89）%]，差异有统计学意义（P＜0.05）。研究组24hUPQ低于对照组[（1.05±0.73）g vs（1.96±0.82）g]，ALB高于对照组[（32.75±5.13）g/L vs（24.83±5.54）g/L]，差异有统计学意义（P＜0.05）；两组Scr比较，差异无统计学意义（P＞0.05）。结论 金水宝片治疗原发性肾病综合征可改善患者血液流变学指标及肾功能，改善预后。
Abstract:
Abstract：Objective To investigate the effect of Jinshuibao tablet on hemorheology in patients with primary nephrotic syndrome.Methods A total of 78 patients with primary nephrotic syndrome admitted to our hospital from January 2018 to February 2019 were enrolled. The patients were divided into the control group and the study group according to the random number table, 39 cases each. Both groups were given conventionality treatments, the control group was given prednisolone tablets, the study group was treated with Jinshuibao tablet on the basis of the control group, and the blood rheology and renal function indexes were compared between the two groups.Results The whole blood viscosity of the study group was low, the whole blood viscosity was high, the plasma viscosity and hematocrit were lower than the control group [(8.42±2.03) mPa·s vs (10.59±2.14) mPa·s], [(3.94± 1.22) mPa·s vs (6.36±1.30) mPa·s], [(1.32±0.21) mPa·s vs (1.80±0.34) mPa·s], [(42.10±2.53)% vs (46.18±2.89)% ], the difference was statistically significant (P< 0.05). The 24h UPQ of the study group was lower than that of the control group [(1.05±0.73) g vs (1.96±0.82) g], and the ALB was higher than the control group [(32.75±5.13) g/L vs (24.83±5.54) g/L], the difference statistically significant (P<0.05); there was no significant difference in Scr between the two groups (P>0.05).Conclusion Jinshuibao tablet can improve the hemorheology and renal function and improve the prognosis of patients with primary nephrotic syndrome.

参考文献/References:

[1]雷文娟,张铿,潘庆军,等.原发性肾病综合征患者急性肾损伤标志物的检测及其意义[J].中国中西医结合肾病杂志,2016,17(6):499-501. [2]陈春梅,夏运成.成人原发性肾病综合征病理类型与激素疗效的关系[J].广东医学,2015,36(7):1040-1042. [3]安超,马赛箭,薛文娇,等.HPLC法测定冬虫夏草菌丝体及发酵液中核苷类成分[J].食品研究与开发,2017,38(1):130-134. [4]康乐,刘晓冬.红花黄色素配伍金水宝对原发性肾病综合征患者血脂水平及血液流变学的影响[J].陕西中医,2016,37(1):62-64. [5]齐学林,黄晓红,刘春梅,等.黄芪片联合金水宝胶囊对早期糖尿病肾病患者血尿常规及sICAM-1水平、尿蛋白指标的影响[J].国际检验医学杂志,2018,39(14):1691-1693.

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更新日期/Last Update: 2019-09-15