[1]聂今心,丁振江,段华莹.心力衰竭患者血清脑钠肽和白蛋白相关性分析[J].医学信息,2019,32(05):98-100.[doi:10.3969/j.issn.1006-1959.2019.05.029]
　NIE Jin-xin,DING Zhen-jiang,DUAN Hua-ying.Correlation between Serum Brain Natriuretic Peptide and Albumin in Patients with Heart Failure[J].Medical Information,2019,32(05):98-100.[doi:10.3969/j.issn.1006-1959.2019.05.029]
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心力衰竭患者血清脑钠肽和白蛋白相关性分析()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
32卷
期数:
2019年05期
页码:
98-100
栏目:
论著
出版日期:
2019-03-01

文章信息/Info

Title:
Correlation between Serum Brain Natriuretic Peptide and Albumin in Patients with Heart Failure
文章编号:
1006-1959（2019）05-0098-03
作者:
聂今心; 丁振江; 段华莹
（承德医学院附属医院心脏内科，河北 承德 067000）
Author(s):
NIE Jin-xin; DING Zhen-jiang; DUAN Hua-ying
(Department of Cardiology,the Affiliated Hospital of Chengde Medical College,Chengde 067000,Hebei,China)
关键词:
心力衰竭; 血清脑钠肽; 血清白蛋白
Keywords:
Heart failure; Serum brain natriuretic peptide; Serum albumin
分类号:
R541.6
DOI:
10.3969/j.issn.1006-1959.2019.05.029
文献标志码:
A
摘要:
目的 探讨心力衰竭（HF）患者的血清脑钠肽（BNP）与血清白蛋白（ALB）之间的关系以及低蛋白血症对入选患者近期预后的影响。方法 连续入选承德医学院附属医院本部心脏内科2017年6月~2018年8月收治的HF患者共150例，根据ALB浓度将入选者分为低蛋白血症组（61例）和对照组（89例），在出院第30 d进行随访。结果 低蛋白血症组BNP值（1909.64±1640.90）pg/ml高于对照组（994.67±808.87） pg/ml（P＜0.001），低蛋白血症组谷丙转氨酶（121.21±57.12）U/L高于对照组（49.45±7.63）U/L （P=0.014）。ALB浓度与BNP对数转换值呈负相关（P＜0.01）。低蛋白血症组和对照组患者30 d内HF死亡率分别为6.56%和1.12%（P=0.030），30 d内HF再住院率分别为11.48%和3.37%（P=0.025）。结论 ALB浓度与BNP值呈负相关，合并低蛋白血症的HF患者近期预后不良。
Abstract:
Objective To investigate the relationship between serum brain natriuretic peptide (BNP) and serum albumin (ALB) in patients with heart failure (HF) and the effect of hypoproteinemia on the short-term prognosis of enrolled patients. Methods A total of 150 patients with HF admitted to the Department of Cardiology, Affiliated Hospital of Chengde Medical College from June 2017 to August 2018 were enrolled. The patients were divided into hypoproteinemia group (61 cases)and The control group (89 cases) was followed up on the 30 d after discharge. Results The BNP value of the hypoproteinemia group (1909.64±1640.90) pg/ml was higher than that of the control group (994.67±808.87) pg/ml (P<0.001), and the hypoproteinemia group alanine aminotransferase (121.21±57.12) U/L. It was higher than the control group (49.45±7.63) U/L (P=0.014). The ALB concentration was negatively correlated with the BNP logarithmic conversion value (P<0.01). The HF mortality rate was 6.56% and 1.12% (P=0.030) in the hypoproteinemia group and the control group, respectively, and the HF rehospitalization rate was 11.48% and 3.37% (P=0.025) within 30 d. Conclusion The ALB concentration is negatively correlated with the BNP value. The HF patients with hypoproteinemia have a poor prognosis in the near future.

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更新日期/Last Update: 2019-03-01