[1]蔡 振,桑畅野.早期乳腺癌前哨淋巴结活检术的临床应用[J].医学信息,2019,32(06):114-116.[doi:10.3969/j.issn.1006-1959.2019.06.035]
　CAI Zhen,SANG Chang-ye.Clinical Application of Sentinel Lymph Node Biopsy in Early Breast Cancer[J].Journal of Medical Information,2019,32(06):114-116.[doi:10.3969/j.issn.1006-1959.2019.06.035]
点击复制

早期乳腺癌前哨淋巴结活检术的临床应用()
分享到：

医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
32卷
期数:
2019年06期
页码:
114-116
栏目:
临床研究
出版日期:
2019-03-15

文章信息/Info

Title:
Clinical Application of Sentinel Lymph Node Biopsy in Early Breast Cancer
文章编号:
1006-1959（2019）06-0114-03
作者:
蔡 振; 桑畅野
（北京市延庆区医院/北京大学第三医院延庆医院普外科，北京 102100）
Author(s):
CAI Zhen; SANG Chang-ye
(Beijing Yanqing District Hospital/Department of General Surgery,Yanqing Hospital,Peking University Third Hospital,Beijing 102100,China)
关键词:
早期乳腺癌; 前哨淋巴结活检术; 腋窝清扫
Keywords:
Early breast cancer; Sentinel lymph node biopsy; Axillary dissection
分类号:
R737.9
DOI:
10.3969/j.issn.1006-1959.2019.06.035
文献标志码:
A
摘要:
目的 分析早期乳腺癌前哨淋巴结活检术临床应用的效果。方法 选取我院2016年1月~2018年1月收治的乳腺癌患者60例，按照患者意愿及手术适应证分为对照组和实验组。对照组28例直接行保乳根治术，实验组32例根据前哨淋巴结活检术病理结果确定是否进行腋窝清扫术。比较两组患者疼痛、麻木、上肢水肿、活动障碍、皮下积液等并发症发生率、手术时间、住院时间、有无肿瘤复发情况、对美容效果满意率。结果 实验组患者术后3个月并发症发生率（21.88%）低于对照组（71.42%），术后6个月并发症发生率（3.13%）低于对照组（25.00%），实验组患者平均手术时间及住院时间均低于对照组，差异有统计学意义（P＜0.05）；对照组患者局部转移率高于实验组，两组患者复发情况比较，差异无统计学意义（P＞0.05）；术后美容效果满意度实验组高于对照组，差异有统计学意义（P＜0.05）。结论 在早期乳腺癌患者中应用前哨淋巴结活检术可以在不增加复发率的基础上，有效降低术后并发症发生率、降低住院时间及腋窝引流时间，提高整体美容效果。
Abstract:
Objective To analyze the clinical application of sentinel lymph node biopsy in early breast cancer. Methods 60 patients with breast cancer admitted to our hospital from January 2016 to January 2018 were enrolled. The patients were divided into the control group and the experimental group according to the patient's wishes and surgical indications. In the control group, 28 patients underwent radical mastectomy. In the experimental group, 32 patients underwent axillary dissection according to the pathological results of sentinel lymph node biopsy. The incidence of complications such as pain, numbness, upper extremity edema, activity disorder, subcutaneous effusion, operation time, hospitalization time, tumor recurrence, and satisfaction rate of cosmetic effects were compared between the two groups. Results The incidence of complications at 3 months after operation (21.88%) in the experimental group was lower than that in the control group (71.42%), and the incidence of complications in the 6 months after operation (3.13%) was lower than that in the control group (25.00%). The average operative time and hospitalization time in the experimental group were significantly lower than those in the control group,the difference was statistically significant (P<0.05). The local metastasis rate of the control group was higher than that of the experimental group. There was no significant difference in the recurrence between the two groups (P>0.05).The postoperative cosmetic effect satisfaction group was higher than the control group,the difference was statistically significant (P<0.05). Conclusion The use of sentinel lymph node biopsy in patients with early breast cancer can effectively reduce the incidence of postoperative complications, reduce the length of hospital stay and axillary drainage time, and improve the overall cosmetic effect without increasing the recurrence rate.

参考文献/References:

[1]鲍艳,贾建光,朱静.前哨淋巴结活检联合乳房区段切除术治疗早期乳腺癌患者的围手术期护理观察[J].中华全科医学,2018,16(10):1753-1756. [2]王凤宝,袁凤坤.保乳术联合前哨淋巴结活检手术治疗老年乳腺癌患者的临床效果观察[J].中国医疗设备,2017,32(S1):61. [3]颜宁,刘少杰,彭伟强,等.早期乳腺癌前哨淋巴结活检对预测腋窝淋巴结状态的临床探讨[J].当代医学,2013,19(1):107-108. [4]陈旭明,郭巨江,翁一尹,等.超声引导下麦默通活检术在多发乳腺病灶中诊断早期乳腺癌的意义[J]. 中国普通外科杂志,2016,25(5):773-775. [5]吴克瑾.美国肿瘤学会《早期乳腺癌病人前哨淋巴结活检指南》更新介绍与解读[J].中国实用外科杂志,2015,35(1):25-26. [6]赵亚东,井自良,杜江.前哨淋巴结活检在早期浸润性乳腺癌保乳手术中的应用[J].局解手术学杂志,2018,27(11):826-830. [7]夏雯,郑秋帆,覃涛,等.术前CA15-3和CEA水平在接受托瑞米芬治疗的管腔型可手术乳腺癌患者中的预后价值[J].中山大学学报(医学科学版),2016,37(6):858-868. [8]Elmadahm AA,Gill PG,et al.Identification of the sentinel lymph node in the SNAC-1 trial[J].ANZ J Surg,2015,85(1-2):58-63. [9]陈宏亮,丁昂,王富文,等.前哨淋巴结阳性的乳腺癌患者非前哨淋巴结转移影响因素分析[J].复旦学报(医学版),2015,42(4):460-466. [10]朱会生,卢文献,任芳芳.保乳加前哨淋巴结活检术与乳腺癌改良根治术治疗乳腺癌疗效对比分析[J].赣南医学院学报,2018,38(8):785-790. [11]中国抗癌协会乳腺癌专业委员会.中国抗癌协会乳腺癌诊治指南与规范(2017年版)[J].中国癌症杂志,2017,27(9):695-760.

相似文献/References:

[1]邱文风,聂 颖,夏蓉晖,等.彩色超声联合乳腺钼靶检查在早期乳腺癌筛查中的应用价值[J].医学信息,2022,35(12):166.[doi:10.3969/j.issn.1006-1959.2022.12.041]
　QIU Wen-feng,NIE Ying,XIA Rong-hui,et al.Application Value of Color Ultrasound Combined with Mammography in Early Breast Cancer Screening[J].Journal of Medical Information,2022,35(06):166.[doi:10.3969/j.issn.1006-1959.2022.12.041]
[2]谭 添,李义强,吴 悦.早期乳腺癌保留乳腺手术治疗的临床效果[J].医学信息,2019,32(10):112.[doi:10.3969/j.issn.1006-1959.2019.10.036]
　TAN Tian,LI Yi-qiang,WU Yue.Clinical Effect of Breast Cancer Preservation in Early Breast Cancer[J].Journal of Medical Information,2019,32(06):112.[doi:10.3969/j.issn.1006-1959.2019.10.036]
[3]杜 宁.保乳手术与改良根治术对早期乳腺癌患者生活质量的影响[J].医学信息,2020,33(06):118.[doi:10.3969/j.issn.1006-1959.2020.06.036]
　DU Ning.Effect of Breast-conserving Surgery and Modified Radical Surgery on Quality of Life in Patients with Early Breast Cancer[J].Journal of Medical Information,2020,33(06):118.[doi:10.3969/j.issn.1006-1959.2020.06.036]

更新日期/Last Update: 2019-03-15