[1]镡子鸣,叶怀阔,任长杰.超敏C反应蛋白及妊娠相关血浆蛋白A预测再发急性冠脉综合征的临床价值[J].医学信息,2019,32(08):173-175.[doi:10.3969/j.issn.1006-1959.2019.08.055]
　TAN Zi-ming,YE Huai-kuo,et al.Clinical Value of High-sensitivity C-reactive Protein and Pregnancy-associated Plasma Protein A in Predicting Recurrent Acute Coronary Syndrome[J].Journal of Medical Information,2019,32(08):173-175.[doi:10.3969/j.issn.1006-1959.2019.08.055]
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超敏C反应蛋白及妊娠相关血浆蛋白A预测再发急性冠脉综合征的临床价值()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
32卷
期数:
2019年08期
页码:
173-175
栏目:
诊疗技术
出版日期:
2019-04-15

文章信息/Info

Title:
Clinical Value of High-sensitivity C-reactive Protein and Pregnancy-associated Plasma Protein A in Predicting Recurrent Acute Coronary Syndrome
文章编号:
1006-1959（2019）08-0173-03
作者:
镡子鸣1; 2; 叶怀阔2; 任长杰2
（1.济南大学山东省医学科学院医学与生命科学学院，山东 济南 250200；2.济宁市第一人民医院心内科，山东 济宁 272200）
Author(s):
TAN Zi-ming1;  2; YE Huai-kuo2; REN Chang-jie2
(1.School of Medicine and Life Science,Shandong Academy of Medical Sciences,Jinan University, Jinan 250200, Shandong,China;2.Department of Cardiology,the First People's Hospital of Jining,Jining 272200,Shandong,China)
关键词:
冠心病; 急性冠脉综合征; 妊娠相关血浆蛋白A; 超敏C反应蛋白
Keywords:
Coronary heart disease; Acute coronary syndrome; Pregnancy-related plasma protein A;  Hypersensitive C-reactive protein
分类号:
R541.4
DOI:
10.3969/j.issn.1006-1959.2019.08.055
文献标志码:
A
摘要:
目的 探讨冠心病患者的超敏C反应蛋白及妊娠相关血浆蛋白A在预测1年内是否再发急性冠脉综合征的临床价值。方法 收集我院心内科2017年3月~2017年8月收治的冠心病患者50例，根据患者1年内是否发生急性冠脉综合征分为A（10例，发生）、B（40例，未发生）两组，记录超敏C反应蛋白、妊娠相关血浆蛋白A水平，分析其与患者1年内再发急性冠脉综合征的关系。结果 A、B两组患者年龄比较，差异有统计学意义（P＜0.05）；A组患者超敏C反应蛋白及妊娠相关血浆蛋白A水平均高于B组，差异有统计学意义（P＜0.05）；Logistic 回归分析显示，年龄及超敏C反应蛋白、妊娠相关血浆蛋白A均与再发急性冠脉综合征有关（P＜0.05），妊娠相关血浆蛋白A在急性冠脉综合征预测中意义更高（P＜0.05）。结论 冠心病患者再发急性冠脉综合征与年龄、超敏C反应蛋白、妊娠相关血浆蛋白A均有关，而妊娠相关血浆蛋白A可以更好的预测急性冠脉综合征。
Abstract:
Objective To investigate the clinical value of high-sensitivity C-reactive protein and pregnancy-associated plasma protein A in patients with coronary heart disease in predicting recurrence of acute coronary syndrome within 1 year.Methods A total of 50 patients with coronary heart disease admitted to our department of cardiology from March 2017 to August 2017 were enrolled. According to whether the patients developed acute coronary syndrome within 1 year, they were divided into A (10 cases, occurrence) and B (40 cases, no occurrence). The two groups were recorded, and the levels of hypersensitive C-reactive protein and pregnancy-associated plasma protein A were recorded, and the relationship between the patients with acute coronary syndrome and recurrence of coronary syndrome within 1 year was analyzed. Results The ages of the two groups were significantly different (P<0.05). The levels of high-sensitivity C-reactive protein and pregnancy-related plasma protein A in group A were higher than those in group B (P<0.05); Logistic regression analysis showed that age and hypersensitive C-reactive protein and pregnancy-associated plasma protein A were associated with recurrent acute coronary syndrome (P<0.05), and pregnancy-associated plasma protein A was predicted in acute coronary syndrome, the significance is higher (P<0.05). Conclusion Recurrent acute coronary syndrome in patients with coronary heart disease is associated with age, hypersensitive C-reactive protein, and pregnancy-associated plasma protein A, and pregnancy-associated plasma protein A can better predict acute coronary syndrome.

参考文献/References:

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更新日期/Last Update: 2019-04-15