[1]席晓平.自拟益气和胃汤联合mFOLFOX6化疗治疗晚期直肠癌疗效观察[J].医学信息,2019,32(09):163-164.[doi:10.3969/j.issn.1006-1959.2019.09.055]
 XI Xiao-ping.Self-made Yiqihewei Decoction Combined with mFOLFOX6 Chemotherapy in the Treatment of Advanced Rectal Cancer[J].Journal of Medical Information,2019,32(09):163-164.[doi:10.3969/j.issn.1006-1959.2019.09.055]
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自拟益气和胃汤联合mFOLFOX6化疗治疗晚期直肠癌疗效观察()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
32卷
期数:
2019年09期
页码:
163-164
栏目:
中医中药
出版日期:
2019-05-01

文章信息/Info

Title:
Self-made Yiqihewei Decoction Combined with mFOLFOX6 Chemotherapy in the Treatment of Advanced Rectal Cancer
文章编号:
1006-1959(2019)09-0163-02
作者:
席晓平
(重庆市铜梁区中医院肾病、肿瘤科,重庆 402560)
Author(s):
XI Xiao-ping
(Department of Nephrology and Oncology,Tongliang District Chinese Medicine Hospital,Chongqing 402560,China)
关键词:
晚期直肠癌益气和胃汤mFOLFOX6CEA生活质量
Keywords:
Advanced rectal cancerYiqihewei DecoctionmFOLFOX6CEAQuality of life
分类号:
R735.3+7
DOI:
10.3969/j.issn.1006-1959.2019.09.055
文献标志码:
A
摘要:
目的 观察晚期直肠癌应用自拟益气和胃汤与mFOLFOX6化疗联合治疗的疗效、CEA水平及生活质量。方法 临床资料采集2015年7月~2018年7月我院收治的60例晚期直肠癌患者,随机分为两组,每组30例,对照组行mFOLFOX6化疗,观察组在其基础服用益气和胃汤治疗,比较两组疗效、CEA及生活质量。结果 观察组治疗总有效率为93.33%,高于对照组的66.67%,差异有统计学意义(P<0.05);观察组的血清CEA水平和生活质量均优于对照组,差异有统计学意义(P<0.05)。结论 晚期直肠癌应用自拟益气和胃汤与mFOLFOX6化疗联合治疗效果显著,有助于抑制癌胚抗原水平,控制病情,改善生活质量。
Abstract:
Objective To observe the efficacy, CEA level and quality of life of the combination of Yiqihewei Decoction and mFOLFOX6 chemotherapy in the treatment of advanced rectal cancer. Methods Clinical data were collected from 60 patients with advanced rectal cancer admitted to our hospital from July 2015 to July 2018. They were randomly divided into two groups, 30 patients in each group. The control group received mFOLFOX6 chemotherapy, and the observation group took Qi and Weitang treatment, comparing the efficacy, CEA and quality of life of the two groups. Results The total effective rate of the observation group was 93.33%, which was higher than that of the control group 66.67%,the difference was statistically significant (P<0.05). The serum CEA level and quality of life of the observation group were better than the control group,the difference was statistically significant(P<0.05). Conclusion The application of self-made Yiqihewei Decoction combined with mFOLFOX6 chemotherapy in advanced rectal cancer is effective, which can inhibit the level of carcinoembryonic antigen, control the disease and improve the quality of life.

参考文献/References:

[1]金小民,孙岩,何剑.奥沙利铂联合替吉奥与FOLFOX4化疗方案治疗晚期结直肠癌的疗效及不良反应评价[J].中华全科医学,2015,13(5):852-853.
[2]王建刚,张帆,孔娜,等.胎盘多肽注射液联合mFOLFOX6方案对结直肠癌患者术后血脂及不良反应的影响[J].药物评价研究,2018,41(8):1481-1485.
[3]中华人民共和国国家卫生和计划生育委员会医政医管局,中华医学会肿瘤学分会.中国结直肠癌诊疗规范(2017年版)[J].中国实用外科杂志,2018(10):1089-1103.
[4]中华中医药学会发布.肿瘤中医诊疗指南[M].北京:中国中医药出版社,2008:1-82.
[5]张彦博,刘宣,季青,等.健脾解毒方联合化疗治疗转移性结直肠癌临床研究[J].中华中医药杂志,2015,30(6):2090-2093.
[6]惠广盈,刘楠.卡培他滨与奥沙利铂联合应用对晚期结直肠癌患者免疫功能及生活质量的影响[J].中国肿瘤临床与康复,2018,25(10):1220-1223.
[7]樊晓静,史志涛,孙昕.活血健脾中药联合顺铂化疗对直肠癌患者肿瘤相关指标、Karnofsky评分及ECOG评分的影响分析[J].中华中医药学刊,2017,35(11):2969-2972.
[8]姚嵋方,李凤云,刘志,等.FOLFOX4方案联合益气健脾汤治疗结直肠癌的临床研究[J].中国临床药理学杂志,2016,32(18):1663-1665,1669.
[9]李国梁.自拟益气和胃汤对消化性溃疡患者胃泌素表达水平的影响[J].四川中医,2017(9):78-80.
[10]李莉,任娟,郭峰,等.CEA在结直肠癌肿瘤的表达特征及其对微转移的预测价值[J].结直肠肛门外科,2016,22(4):361-364.

更新日期/Last Update: 2019-05-01