[1]李前进,马惠斌,郑双峰,等.经尿道膀胱黏膜电凝术联合甲醛溶液灌注治疗出血性放射性膀胱炎的临床效果[J].医学信息,2019,32(09):187-188.[doi:10.3969/j.issn.1006-1959.2019.09.064]
　LI Qian-jing,MA Hui-bin,ZHENG Shuang-feng,et al.Effect of Transurethral Bladder Mucosal Electrocoagulation Combined with Formaldehyde Solution in the Treatment of Hemorrhagic Radiation Cystitis[J].Journal of Medical Information,2019,32(09):187-188.[doi:10.3969/j.issn.1006-1959.2019.09.064]
点击复制

经尿道膀胱黏膜电凝术联合甲醛溶液灌注治疗出血性放射性膀胱炎的临床效果()
分享到：

医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
32卷
期数:
2019年09期
页码:
187-188
栏目:
出版日期:
2019-05-01

文章信息/Info

Title:
Effect of Transurethral Bladder Mucosal Electrocoagulation Combined with Formaldehyde Solution in the Treatment of Hemorrhagic Radiation Cystitis
文章编号:
1006-1959（2019）09-0187-02
作者:
李前进; 马惠斌; 郑双峰; 王文光; 马 涛
（新疆医科大学第一附属医院泌尿外科，新疆 乌鲁木齐 830054）
Author(s):
LI Qian-jing; MA Hui-bin; ZHENG Shuang-feng; WANG Wen-guang; MA Tao
(Department of Urology,the First Affiliated Hospital of Xinjiang Medical University,Urumqi 830054,Xinjiang,China)
关键词:
放射性膀胱炎; 膀胱灌注; 经尿道膀胱黏膜电凝术; 2.5%甲醛溶液
Keywords:
Radiation cystitis; Intravesical instillation; Transurethral bladder mucosa electrocoagulation; 2.5% formaldehyde solution
分类号:
R730.55
DOI:
10.3969/j.issn.1006-1959.2019.09.064
文献标志码:
A
摘要:
目的 观察放射性膀胱炎患者接受经尿道膀胱黏膜电凝术联合2.5%甲醛溶液膀胱灌注治疗的临床效果及安全性。方法 选择2012年6月~2016年6月我院收治的21 例放射性膀胱炎患者，均行经尿道膀胱黏膜电凝术联合2.5%甲醛溶液膀胱灌注治疗，记录患者术前、术后1个月、术后3个月血红蛋白水平，比较患者术前及术后1个月血尿分级水平，随访2年内患者并发症情况。结果 患者术前、术后1个月、术后3个月血红蛋白水平分别为（65.10±15.43）g/L、（93.24±12.01）g/L、（106.62±11.65）g/L，差异均有统计学意义（P＜0.05）；患者术前及术后1个月血尿分级比较，差异具有统计学意义（P＜0.05）；所有患者随访2年中均未见膀胱挛缩情况，无再出血患者。21例患者中2例患者术后出现尿频、尿急症状，给予对症治疗后，患者症状明显改善。结论 经尿道膀胱黏膜电凝术联合2.5%甲醛溶液膀胱灌注治疗放射性膀胱炎不良反应较少，安全性较高，可有效改善患者血尿情况。
Abstract:
Objective To observe the clinical efficacy and safety of transurethral bladder mucosal electrocoagulation combined with 2.5% formaldehyde solution for bladder perfusion in patients with radiation cystitis.Methods 21 patients with radiation cystitis admitted to our hospital from June 2012 to June 2016 were treated with transurethral bladder mucosal electrocoagulation combined with 2.5% formaldehyde solution for bladder perfusion. The patients were recorded before and 1 month after surgery. The hemoglobin level was 3 months after operation, and the hematuria grading level before and 1 month after surgery was compared. The complications of the patients were followed up for 2 years.Results The hemoglobin levels of patients before operation, 1 month after operation and 3 months after operation were (65.10±15.43)g/L, (93.24±12.01)g/L, and (106.62±11.65)g/L, respectively,the difference was statistically significant (P<0.05), and there was significant difference in hematuria grading before operation and one month after operation (P<0.05). No bladder contracture was found in all patients during the follow-up of 2 years, and there was no rebleeding. Of the 21 patients, 2 had frequent urination and acute urinary symptoms, and the symptoms of the patients improved obviously after treatment with symptomatic treatment.Conclusion Transurethral bladder mucosal electrocoagulation combined with 2.5% formaldehyde solution for intravesical instillation of radioactive cystitis has fewer adverse reactions and higher safety, which can effectively improve hematuria.

参考文献/References:

[1]邵起辉.出血性放射性膀胱炎的治疗及其体会[J].中国医药指南,2012,10(8):76-77.
[2]杨顺利,杨立杰.透明质酸钠联合复方苦参注射液治疗放射性膀胱炎临床研究[J].中国药业,2016,25(8):62-63,64.
[3]程志刚,魏辉,黄英,等.膀胱水压扩张联合药物灌注治疗氯胺酮相关性膀胱炎的长期随访研究[J].中华泌尿外科杂志,2017,38(1):28-32.
[4]李强,王大亚.经尿道膀胱内电灼止血及透明质酸钠膀胱灌注治疗放射性膀胱炎出血的临床研究[J].中国中西医结合外科杂志,2015,35(3):224-226.
[5]巫嘉文,余洋.高压氧综合治疗出血性放射性膀胱炎56例疗效观察[J].中华航海医学与高气压医学杂志,2016,23(4):323-325.
[6]段晶晶,孔为民.放射性膀胱炎的诊治进展[J].医学综述,2015,(14):2588-2590.
[7]刘成,姚东伟,刘雪军,等.经尿道半导体激光汽化术治疗出血性放射性膀胱炎[J].国际泌尿系统杂志,2017,37(4):529-532.
[8]彭昆,高文强,邱雪峰等.丹参酮Ⅰ通过激活Nrf2-ARE通路阻抑放射性膀胱炎早期损伤的形成[J].现代泌尿外科杂志,2018,23(7):533-538,552.
[9]常凯.内镜微创联合膀胱内灌注在女性腺性膀胱炎中的应用价值分析[J].中国内镜杂志,2015,21(3):259-262.
[10]居正华,李有元,韩惟青,等.5步序贯法治疗放射性膀胱炎出血的临床研究[J].中华泌尿外科杂志,2018,39(12):890-894.
[11]苏剑锋,朱震平,冯庆.等离子电灼联合膀胱灌注透明质酸钠治疗放射性膀胱炎的临床效果观察[J].中国现代药物应用,2018,12(15):21-23.

相似文献/References:

[1]黄 毅,吴 桥,朱光强,等.膀胱灌注和经尿道电凝治疗出血性放射性膀胱炎效果的Meta分析[J].医学信息,2021,34(10):97.[doi:10.3969/j.issn.1006-1959.2021.10.026]
　HUANG Yi,WU Qiao,ZHU Guang-qiang,et al.Meta Analysis of the Effects of Bladder Perfusion and Transurethral Electrocoagulation in the Treatment of Hemorrhagic Radiation Cystitis[J].Journal of Medical Information,2021,34(09):97.[doi:10.3969/j.issn.1006-1959.2021.10.026]

更新日期/Last Update: 2019-05-01