[1]郑 伟.诱骗受体3γ-干扰素和抗环瓜氨酸肽抗体在风湿性关节炎患者血清中的表达[J].医学信息,2019,32(19):97-98101.[doi:10.3969/j.issn.1006-1959.2019.19.029]
 ZHENG Wei.Expression of Decoy Receptor 3γ-Interferon and Anti-Cyclic Citrullinated Peptide Antibody in Serum of Patients with Rheumatoid Arthritis[J].Journal of Medical Information,2019,32(19):97-98101.[doi:10.3969/j.issn.1006-1959.2019.19.029]
点击复制

诱骗受体3γ-干扰素和抗环瓜氨酸肽抗体在风湿性关节炎患者血清中的表达()
分享到:

医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
32卷
期数:
2019年19期
页码:
97-98101
栏目:
临床研究
出版日期:
2019-10-01

文章信息/Info

Title:
Expression of Decoy Receptor 3γ-Interferon and Anti-Cyclic Citrullinated Peptide Antibody in Serum of Patients with Rheumatoid Arthritis
文章编号:
1006-1959(2019)19-0097-03
作者:
郑 伟
(蒙古族自治县蒙医医院检验科,辽宁 阜新 123100)
Author(s):
ZHENG Wei
(Department of Clinical Laboratory,Mongolian Medical Hospital of Mongolian Autonomous County,Fuxin 123100,Liaoning,China)
关键词:
血清诱骗受体3γ-干扰素抗环瓜氨酸肽抗体风湿性关节炎
Keywords:
Serum decoy receptor 3γ-interferonAnti-cyclic citrullinated peptide antibodyRheumatoid arthritis
分类号:
R593.22
DOI:
10.3969/j.issn.1006-1959.2019.19.029
文献标志码:
A
摘要:
目的 分析在风湿性关节炎患者中抗环瓜氨酸肽抗体、血清诱骗受体3γ-干扰素检验有效性。方法 选择2018年1月~12月我院收治的风湿性关节炎患者50例作为观察组,另选同期体检健康人群40例作为对照组,检测并比较两组血清抗环瓜氨酸肽抗体、血清诱骗受体3γ-干扰素水平。结果 观察组抗环瓜氨酸肽抗体、风湿因子检测结果高于对照组,差异有统计学意义(P<0.05);观察组单一抗环瓜氨酸肽抗体检测阳性率、单一风湿因子检测阳性率均高于对照组,观察组抗环瓜氨酸肽抗体联合风湿因子检测阳性率高于对照组,差异均有统计学意义(P<0.05);观察组抗环瓜氨酸肽抗体、血清诱骗受体3γ-干扰素含量比对照组高,差异有统计学意义(P<0.05)。结论 在风湿性关节炎患者中抗环瓜氨酸肽抗体、血清诱骗受体3γ-干扰素检验,能够明确患者临床指标情况,对于临床治疗有参考价值,值得应用。
Abstract:
Objective To analyze the effectiveness of anti-cyclic citrullinated peptide antibody and serum decoy receptor 3γ-interferon in patients with rheumatoid arthritis. Methods 50 patients with rheumatoid arthritis admitted to our hospital from January to December 2018 were selected as observation group, and 40 healthy subjects in the same period were selected as the control group. The serum anti-cyclic citrullinated peptide antibodies were detected and compared. Serum decoy receptor 3γ-interferon levels.Results The anti-cyclic citrullinated peptide antibody and rheumatoid factor in the observation group were higher than the control group,the difference was statistically significant (P<0.05). The positive rate of single anti-cyclic citrullinated peptide antibody and the positive rate of single rheumatoid factor in the observation group. The positive rate of anti-cyclic citrullinated peptide antibody combined with rheumatoid factor was higher in the observation group than in the control group, the difference was statistically significant (P<0.05); the anti-cyclic citrullinated peptide antibody and serum decoy in the observation group The content of receptor 3γ-interferon was higher than that of the control group,the difference was statistically significant (P<0.05).Conclusion In the patients with rheumatoid arthritis, anti-cyclic citrullinated peptide antibody and serum decoy receptor 3γ-interferon test can confirm the clinical indicators of patients, which has reference value for clinical treatment and is worthy of application.

参考文献/References:

[1]李新秀.联合检测风湿因子、抗CCP抗体、免疫球蛋白对辅助诊断风湿性关节炎的价值探讨[J].中外医疗,2019,38(2):22-24. [2]林丽文,吕慧,吴险.联合检测抗环瓜氨酸肽抗体、抗角蛋白抗体和风湿因子对风湿性关节炎的诊断价值[J].临床检验杂志(电子版),2019,8(1):27-29. [3]王晓霞,王洪,刘丹.风湿关节炎患者外周血血小板参数变化与Th17调节性T细胞及疾病活动的相关性分析[J].中国药物与临床,2019,19(1):4-7. [4]尹春香,王晓非.类风湿关节炎患者干扰素调节因子4基因表达变化的研究[J].中国医科大学学报,2013,42(11):1019-1021. [5]舒碧莹,蔡枫.甲氨蝶呤联合蠲痹补肾汤治疗风湿性关节炎疗效及对ESR、CRP、RF、抗CCP抗体的影响[J].国际检验医学杂志,2018,39(24):3032-3035. [6]高明,杨晓英,毛晓莉.抗β2糖蛋白Ⅰ抗体、膜糖蛋白GPⅠb及抗链球菌溶血素O检测在风湿关节炎急性阶段的诊断价值[J].国际检验医学杂志,2019,40(5):575-578. [7]魏禺,唐小军,耿林玉,等.人脐带间充质干细胞与风湿关节炎成纤维样滑膜细胞共培养上调可溶性血管内皮生长因子受体1表达[J].中华风湿病学杂志,2018,22(10):691-694.

相似文献/References:

[1]黄 倩,李 涛,谢 艳,等.阿巴西普治疗抗环瓜氨酸肽抗体阳性类风湿关节炎的临床研究进展[J].医学信息,2023,36(09):168.[doi:10.3969/j.issn.1006-1959.2023.09.037]
 HUANG Qian,LI Tao,XIE Yan,et al.Clinical Research Progress of Abatacept in the Treatment of Anti-cyclic Citrullinated Peptide Antibody Positive Rheumatoid Arthritis[J].Journal of Medical Information,2023,36(19):168.[doi:10.3969/j.issn.1006-1959.2023.09.037]

更新日期/Last Update: 2019-10-01