[1]罗雷雷.醒脑静治疗急性脑出血的疗效及对血清hs-CRP和NSE的影响[J].医学信息,2019,32(23):149-151.[doi:10.3969/j.issn.1006-1959.2019.23.046]
　LUO Lei-lei.Effect of Xingnaojing on Acute Cerebral Hemorrhage and its Effect on Serum hs-CRP and NSE[J].Medical Information,2019,32(23):149-151.[doi:10.3969/j.issn.1006-1959.2019.23.046]
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醒脑静治疗急性脑出血的疗效及对血清hs-CRP和NSE的影响()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
32卷
期数:
2019年23期
页码:
149-151
栏目:
药物与临床
出版日期:
2019-12-01

文章信息/Info

Title:
Effect of Xingnaojing on Acute Cerebral Hemorrhage and its Effect on Serum hs-CRP and NSE
文章编号:
1006-1959（2019）23-0149-03
作者:
罗雷雷
（天津市环湖医院神经内科，天津 300350）
Author(s):
LUO Lei-lei
(Department of Neurology,Tianjin Huanhu Hospital,Tianjin 300350,China)
关键词:
醒脑静注射液; 急性脑出血; 血清hs-CRP ; NSE
Keywords:
Xingnaojing injection; Acute cerebral hemorrhage; Serum hs-CRP; NSE
分类号:
R285.6；R743.34
DOI:
10.3969/j.issn.1006-1959.2019.23.046
文献标志码:
A
摘要:
目的 分析醒脑静注射液治疗急性脑出血的临床疗效及对血清hs-CRP和NSE的影响。方法 选择2017年6月~2019年6月在我院治疗的急性脑出血患者108例，采用随机数字表法分为常规组和观察组，各54例。常规组采用常规对症治疗，观察组在常规组治疗基础上辅以醒脑静注射液治疗，比较两组格拉斯哥评分（GCS）、神经功能评分（NIHSS）、血清hs-CRP和神经元特异性烯醇化酶（NSE）水平以及并发症发生率。结果 治疗后两组GCS评分均高于治疗前，且观察组高于常规组，差异有统计学意义（P＜0.05）；治疗后两组NIHSS评分均低于治疗前，且观察组低于常规组，差异有统计学意义（P＜0.05）；治疗后两组血清CShs-CRP、NSE水平均低于治疗前，且观察组低于常规组，差异有统计学意义（P＜0.05）；观察组并发症发生率（3.70%）低于常规组（12.96%），差异有统计学意义（P＜0.05）。结论 醒脑静注射液治疗急性脑出血的临床疗效确切，可有效降低炎症因子和神经受损程度，减少并发症发生，有效改善患者预后效果，具有重要的临床应用价值。
Abstract:
Objective To analyze the clinical efficacy of Xingnaojing injection in the treatment of acute cerebral hemorrhage and its effect on serum hs-CRP and NSE. Methods A total of 108 patients with acute cerebral hemorrhage who were treated in our hospital from June 2017 to June 2019 were randomly divided into the conventional group and the observation group, 54 cases each. The routine group was treated with conventional symptomatic treatment. The observation group was treated with Xingnaojing injection on the basis of routine treatment. The two groups were compared with Glasgow score (GCS), neurological function score (NIHSS), serum hs-CRP and neuron-specific Alcoholase (NSE) levels and the incidence of complications. Results After treatment, the GCS scores of the two groups were higher than those before treatment, and the observation group was higher than the conventional group, the difference was statistically significant (P<0.05). After treatment, the NIHSS scores of the two groups were lower than before treatment, and the observation group was lower than the conventional group,the difference was statistically significant (P<0.05). After treatment, serum CShs-CRP and NSE levels were lower than before treatment, and the observation group was lower than the conventional group, the difference was statistically significant (P<0.05);The incidence of complications in the observation group (3.70%) was lower than that in the conventional group (12.96%),the difference was statistically significant (P<0.05). Conclusion Xingnaojing injection is effective in the treatment of acute cerebral hemorrhage, which can effectively reduce the degree of inflammatory factors and nerve damage, reduce complications, and effectively improve the prognosis of patients. It has important clinical application value.

参考文献/References:

[1]袁芳,高庆春.醒脑静注射液治疗急性脑出血的系统评价[J].中国神经精神疾病杂志,2014,42(1):52-54.[2]刘金星.醒脑静对急性脑梗死患者血浆同型半胱氨酸和超敏C-蛋白的影响[J].中国实用医刊,2015,42(1):65-67.[3]崔娜.醒脑静注射液联合西药治疗急性脑血管病昏迷65例[J].河南中医,2014,18(7):1284-1285.[4]沈长青,刘仲富,奚耀,等.醒脑静注射液治疗急性脑梗死伴意识障碍患者的临床研究[J].云南中医中药杂志,2014,22(8):18-20.[5]余波,史楠,崔建忠,等.醒脑静联合盐酸法舒地尔在高血压脑出血术后的疗效观察[J].中国医院药学杂志,2014,18(18):1589-1592.[6]朱宝贤,张宝国.醒脑静注射液对急性脑出血患者的神经保护作用及机制[J].山东医药,2015,55(33):38-39.

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更新日期/Last Update: 2019-12-01