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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:

33卷

期数:

2020年03期

页码:

105-107

栏目:

临床研究

出版日期:

2020-02-01

文章信息/Info

Title:

Effects of Carotid Atherosclerotic Plaque on the Condition and Recurrence of Patients with Cerebral Infarction

文章编号:

1006-1959（2020）03-0105-03

作者:

李 丹

（抚顺市第二医院神经2科，辽宁 抚顺 113000）

Author(s):

LI Dan

(Department of Neurology,Subject Two,Fushun Second Hospital,Fushun 113000,Liaoning,China)

关键词:

颈动脉粥样; 硬化斑块; 脑梗死; 复发

Keywords:

arotid atherosclerosis; Sclerotic plaque; Cerebral infarction; Relapse

分类号:

R743.3

DOI:

10.3969/j.issn.1006-1959.2020.03.030

文献标志码:

A

摘要:

目的 分析颈动脉粥样硬化斑块对脑梗死患者病情及其复发的影响。方法 回顾分析2018年1月~2019年1月在我院治疗的84例脑梗死患者临床资料，依据超声颈动脉斑块探查结果分为斑块组51例和无斑块组33例。其中斑块组中易损斑块20例，非易损斑块14例、混合斑块17例，比较各组合并糖尿病史、高血压、高纤维蛋白原血症及高脂血症发生率、不同时间神经功能缺损（NIHSS）评分、两组复发率以及复发时间。结果 斑块组合并糖尿病史、高血压、高纤维蛋白原血症及高脂血症发生率均高于无斑块组，差异有统计学意义（P＜0.05）；斑块组第1、7、14天NIHSS评分均高于无斑块组，差异有统计学意义（P＜0.05）；随访6个月，斑块组复发率为23.52%，高于无斑块组的6.06%，平均复发时间为（4.73±0.87）个月，短于无斑块组的（6.42±1.25）个月，差异有统计学意义（P＜0.05）；易损斑块患者复发率为35.00%，高于非易损斑块患者的7.14%，平均复发时间（4.49±0.76）个月，短于非易损斑块患者的（7.33±2.28）个月，差异有统计学意义（P＜0.05）；混合斑块患者复发率、复发时间与易损斑块患者、非易损斑块患者比较，差异无统计学意义（P＞0.05）。结论 颈动脉粥样硬化斑块脑梗死患者更容易复发，尤其是易损斑块患者，临床应给予重视。

Abstract:

Objective To analyze the effect of carotid atherosclerotic plaque on the condition and recurrence of patients with cerebral infarction. Methods The clinical data of 84 patients with cerebral infarction treated in our hospital from January 2018 to January 2019 were retrospectively analyzed. According to the results of ultrasound carotid plaque exploration, they were divided into 51 plaque groups and 33 plaque-free groups. In the plaque group, 20 cases were vulnerable, 14 were non-fragile, and 17 were mixed plaques. The combinations were compared with the history of diabetes, hypertension, hyperfibrinogenemia, and hyperlipidemia. Neurological deficit scores (NIHSS) scores, recurrence rates, and time to relapse in both groups.Results The incidence of plaque combination with diabetes history, hypertension, hyperfibrinogenemia, and hyperlipidemia was higher than that in the plaque-free group,the difference was statistically significant (P<0.05).The plaque group’s NIHSS scores were higher than those without plaque on the 1st, 7th and 14th d,the difference was statistically significant (P<0.05). After 6 months of follow-up, the recurrence rate in the plaque group was 23.52%, which was higher than that in the plaque-free group6.06% in the group, with an average relapse time of (4.73±0.87) months, which was shorter than (6.42±1.25) months in the plaque-free group, the difference was statistically significant (P<0.05); the recurrence rate of patients with vulnerable plaques was 35.00%, which was higher than 7.14% of non-fragile plaque patients. The average recurrence time was (4.49±0.76) months, and shorter than that of non-fragile plaque patients (7.33±2.28) months,the difference was statistically significant (P<0.05); the recurrence rate and recurrence time of patients with mixed plaques were not significantly different from those of vulnerable plaque patients and non-fragile plaque patients (P>0.05).Conclusion Patients with carotid atherosclerotic plaque and cerebral infarction are more likely to relapse, especially those with vulnerable plaque, which should be given clinical attention.

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更新日期/Last Update: 2020-02-01