[1]江龙帆,张 曦.早期妊娠患者血清β-HCG、P、E2水平检测在稽留流产诊断中的价值[J].医学信息,2020,33(06):170-171.[doi:10.3969/j.issn.1006-1959.2020.06.058]
　JIANG Long-fan,ZHANG Xi.Value of Serum β-HCG,P,E2 Levels in Early Pregnancy Patients in the Diagnosis of Missed Abortion[J].Medical Information,2020,33(06):170-171.[doi:10.3969/j.issn.1006-1959.2020.06.058]
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早期妊娠患者血清β-HCG、P、E2水平检测在稽留流产诊断中的价值()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
33卷
期数:
2020年06期
页码:
170-171
栏目:
诊疗技术
出版日期:
2020-03-15

文章信息/Info

Title:
Value of Serum β-HCG,P,E2 Levels in Early Pregnancy Patients in the Diagnosis of Missed Abortion
文章编号:
1006-1959（2020）06-0170-02
作者:
江龙帆; 张 曦
（安徽医科大学附属安庆市立医院妇产科，安徽 安庆 246000）
Author(s):
JIANG Long-fan; ZHANG Xi
(Department of Obstetrics and Gynecology,Anqing Municipal Hospital,Anhui Medical University, Anqing 246000,Anhui,China)
关键词:
早期妊娠; 胚胎停育; β-HCG; 孕酮; 雌二醇
Keywords:
Early pregnancy; Embryo termination; β-HCG; Progesterone; Estradiol
分类号:
R714.22
DOI:
10.3969/j.issn.1006-1959.2020.06.058
文献标志码:
A
摘要:
目的 探讨早期妊娠血清中人绒毛膜促性腺激素（β-HCG）、孕酮（P）、雌二醇（E2）水平检测在稽留流产诊断中的价值。方法选择2017年8月~2019年8月以早期妊娠就诊于安徽医科大学附属安庆市立医院妇产科门诊的孕妇156例，根据妊娠结局分为胚胎停育组（n=71）和正常妊娠组（n=85），各组根据停经天数分为≤42 d、43~49 d、＞49 d，应用化学发光分析法检测两组β-HCG、P、E2水平，比较两组不同停经天数β-HCG、P、E2水平。结果 正常妊娠组不同停经天数血清β-HCG、P、E2水平均高于胚胎停育组，差异有统计学意义（P＜0.05）。结论 胚胎停育患者不同停经天数β-HCG、E2、P水平均较正常妊娠患者低，β-HCG、P、E2水平检测有助于诊断稽留流产。
Abstract:
Objective To investigate the value of detection of human chorionic gonadotropin (β-HCG),progesterone(P)and estradiol(E2)in serum of early pregnancy in the diagnosis of missed abortion.Methods From August 2017 to August 2019,156 pregnant women who were diagnosed with early pregnancy in the Obstetrics and Gynecology clinic of Anqing Municipal Hospital of Anhui Medical University were divided into embryo termination group(n=71)and normal pregnancy group according to pregnancy outcome(n=85).Each group was divided into ≤42 days,43-49 days,and ＞49 days according to the number of menopause days.The levels of β-HCG,P,and E2 were detected by chemiluminescence analysis, and the levels of β-HCG,P,and E2 were compared between the two menopausal days.Results The levels of serum β-HCG,P,and E2 in the different periods of menopause in the normal pregnancy group were higher than those in the embryonic abortion group,the difference was statistically significant(P＜0.05).Conclusion The levels of β-HCG, E2, and P are lower in patients with embryonic abortion than those in normal pregnancy,detection of β-HCG,P,E2 levels is helpful in diagnosing missed abortion.

参考文献/References:

[1]Li Y,Liu X,Sun Y,et al.The Expression of PDCD4 in Patients With Missed Abortion and Its Clinical Significance.[J].Reproductive Sciences,2017,24(11):1512-1519.[2]汪燕凌,袁晓莉.孕妇血清内早期血清妊娠相关激素与胚胎停育的相关性[J].中南医学科学杂志,2019,47(4):433-435.[3]叶菁华,陈以勒,叶亦巍,等.妊娠早期雌二醇监测对妊娠结局预测价值的探讨[J].实用预防医学,2019,26(2):170-172.[4]胡永清.血清孕酮、人绒毛膜促性腺激素及雌二醇联合检测在孕6~8周先兆流产中的临床意义[J].中国卫生产业,2014,11(2):18-19,23.[5]李若薇. 血清E2、P、β-hCG及孕囊胚芽与207例早期先兆流产安胎妇女妊娠结局相关性分析[D].成都中医药大学,2015.[6]高青,王美红,唐蓉.妊娠4~8周孕妇血清雌二醇水平及其与先兆流产的关系[J].山东大学学报(医学版),2008(9):884-886.

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更新日期/Last Update: 2020-03-15