[1]程玉燕,李蔚然,杨 森.2010~2015年合肥市某三甲医院梅毒流行特征报告[J].医学信息,2020,33(10):130-132,136.[doi:10.3969/j.issn.1006-1959.2020.10.038]
　CHENG Yu-yan,LI Wei-ran,YANG Sen.Epidemiological Characteristics of Syphilis in a Top Three Hospital in Hefei from 2010 to 2015[J].Medical Information,2020,33(10):130-132,136.[doi:10.3969/j.issn.1006-1959.2020.10.038]
点击复制

2010~2015年合肥市某三甲医院梅毒流行特征报告()
分享到：

医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
33卷
期数:
2020年10期
页码:
130-132,136
栏目:
调查分析
出版日期:
2020-05-15

文章信息/Info

Title:
Epidemiological Characteristics of Syphilis in a Top Three Hospital in Hefei from 2010 to 2015
文章编号:
1006-1959（2020）10-0130-04
作者:
程玉燕; 李蔚然; 杨 森
（1.安徽医科大学第二附属医院皮肤病与性病科，安徽 合肥 230601；2.安徽医科大学第一附属医院皮肤病与性病科，安徽 合肥 230032）
Author(s):
CHENG Yu-yan; LI Wei-ran; YANG Sen
(1.Department of Dermatology and Venereology,the Second Affiliated Hospital of Anhui Medical University,Hefei 230601,Anhui,China;2.Department of Dermatology and Venereology,the First Affiliated Hospital of Anhui Medical University,Hefei 230032,Anhui,China)
关键词:
梅毒; 潜伏梅毒; 性传播; 合肥市
Keywords:
Syphilis; Latent syphilis; Sexual transmission; Hefei city
分类号:
R759.1
DOI:
10.3969/j.issn.1006-1959.2020.10.038
文献标志码:
A
摘要:
目的 了解合肥地区梅毒的发病年龄及性别等的分布特征，旨在为梅毒的防治提供科学依据。方法 选择2010年1月~2015年12月合肥市某三甲医院皮肤性病科门诊确诊为梅毒的6109例患者进行梅毒流行病学问卷调查，分析其发病年龄、性别、梅毒分期、文化程度及职业分布特征。结果 2010~2013年梅毒发病呈逐年上升趋势，年均增长率为17.56%，2013年达到阶段性高峰，其后逐年下降；主要集中在20~49岁的性活跃人群，女性（55.12%）多于男性（44.88%），无业者居多（25.37%），以初中、高中文化程度者为主，其中初中文化约占35.65%，高中约30.30%；梅毒分期中，以一期、二期、潜伏梅毒为主，其中潜伏梅毒所占比例最高（72.86%）。结论 2010~2015年合肥市梅毒发病呈上升趋势，以20~49岁性活跃人群感染为主，潜伏梅毒检出率最高，应进一步加强梅毒防治的科普宣传力度，对高危人群应及时筛查、尽早干预，预防晚期潜伏梅毒累及重要脏器及向神经梅毒或心血管梅毒转化，从而有效控制梅毒蔓延。
Abstract:
Objective To understand the distribution characteristics of age and sex of syphilis in Hefei area, and to provide a scientific basis for the prevention and treatment of syphilis.Methods From January 2010 to December 2015, 6109 patients diagnosed as syphilis in a dermatology clinic of a top three hospital in Hefei were investigated by syphilis epidemiology questionnaire, and their age, sex, syphilis stage, education level and occupational distribution were analyzed. feature.Results The incidence of syphilis increased year by year from 2010 to 2013, with an average annual growth rate of 17.56%. It reached a staged peak in 2013, and then declined year by year; it was mainly concentrated in sexually active people aged 20 to 49 years, and more women (55.12%) Among males (44.88%), the majority are unemployed (25.37%), mainly those with junior high school and high school education, among which junior high school culture accounts for about 35.65%, high school about 30.30%;Among the stages of syphilis, the first stage, the second stage, and latent syphilis are the main ones, with latent syphilis accounting for the highest proportion (72.86%).Conclusion From 2010 to 2015, the incidence of syphilis in Hefei city is on the rise. The prevalence of sexually active people aged 20 to 49 years is the highest, and the detection rate of latent syphilis is the highest. Intervene as early as possible to prevent late latent syphilis from involving important organs and transforming into neurosyphilis or cardiovascular syphilis, thus effectively controlling the spread of syphilis.

参考文献/References:

[1]齐蔓莉.梅毒的起源和流行病学[J].中国医学文摘(皮肤科学),2015,32(4):334-337.[2]Smajs D,Norris SJ,Weinstock GM.Genetic diversity in Treponema pallidum:implications for pathogenesis,evolution and molecular diagnostics of syphilis and yaws[J].Infect Genet Evol,2012,12(2):191-202.[3]Ghanem KG,Ram S,Rice PA.The Modern Epidemic of Syphilis[J].N Engl J Med,2020,382(9):845-854.[4]胡明霞,李晓静,李照荣.合肥市1991~2004年性病流行病学分析[J].疾病监测,2005(12):627-629,640.[5]潘芳,胡林凤,石泉,等.2011~2015年合肥口岸梅毒监测结果分析[J].中国国境卫生检疫杂志,2016,39(5):324-326.[6]Donovan B,Finlayson RJ,Mutimer K,et al.HIV Infection in Sexually Transmissible Disease Practice in Sydney:The Effects of Legislation,Public Education and Changing ClinicalSpectrum[J].International Journal of Std&Aids,1990,1(1):21-27.[7]Hook EW.Syphilis[J].Lancet,2017,389(10078):1550-1557.[8]龚向东,岳晓丽,滕菲,等.2000-2013年中国梅毒流行特征与趋势分析[J].中华皮肤科杂志,2014,47(5):310-315.[9]Nair TG,Asha LK,Leelakumari PV.An epidemiological study of sexually transmitted diseases[J].Indian J Dermatol Venereol Leprol,2000,66(2):69-72.[10]Tsimis ME,Sheffield JS.Update on syphilis and pregnancy[J].Birth Defects Res,2017,109(5):347-352.[11]Chen XS.Turning off the tap:sustaining elimination of congenital syphilis through the programme targeting high-risk groups[J].J Glob Health,2019,9(2):020312.[12]Land KJ,Boeras DI,Chen XS,et al.REASSURED diagnostics to inform disease control strategies,strengthen health systems and improve patient outcomes[J].Nat Microbiol,2019,4(1):46-54.[13]Pearline RV,Tucker JD,Yuan LF,et al.Sexually transmitted infections among individuals overfifty years of age in China[J].AIDS Patient Care STDS,2010,24(6):345-347.[14]Chin HB,Sipe TA,Elder R,et al.The effectiveness of group-based comprehensive risk-reduction and abstinence education interventions to prevent or reduce the risk of adolescent pregnancy,human immunodeficiency virus,and sexually transmitted infections:two systematic reviews for the Guide to Community Preventive Services[J].Am J Prev Med,2012,42(3):272-294.[15]Mason-Jones AJ,Sinclair D,Mathews C,et al.School-based interventions for preventing HIV,sexually transmitted infections,and pregnancy in adolescents[J].Cochrane Database Syst Rev,2016(11):CD006417.[16]Gomes NC,Meier DA,Pieri FM,et al.Prevalence and factors associated with syphilis in a Reference Center[J].Rev Soc Bras Med Trop,2017,50(1):27-34.

相似文献/References:

[1]杨 凯.苄星青霉素在HIV感染合并梅毒中的临床疗效观察[J].医学信息,2018,31(12):141.[doi:10.3969/j.issn.1006-1959.2018.12.044]
　YANG Kai.Clinical Efficacy of Benzathine Penicillin in HIV Infection with Syphilis[J].Medical Information,2018,31(10):141.[doi:10.3969/j.issn.1006-1959.2018.12.044]
[2]周贤位,杨水秀,肖文革,等.梅毒患者血清学检测结果分析[J].医学信息,2022,35(11):16.[doi:10.3969/j.issn.1006-1959.2022.11.005]
　ZHOU Xian-wei,YANG Shui-xiu,XIAO Wen-ge,et al.Analysis of Serological Test Results of Syphilis Patients[J].Medical Information,2022,35(10):16.[doi:10.3969/j.issn.1006-1959.2022.11.005]
[3]陶春妃.TP-光激化学发光、TPPA、TRUST试验的临床应用评价[J].医学信息,2019,32(23):164.[doi:10.3969/j.issn.1006-1959.2019.23.052]
　TAO Chun-fei.Clinical Application Evaluation of TP-photoexcited Chemiluminescence,TPPA and TRUST Test[J].Medical Information,2019,32(10):164.[doi:10.3969/j.issn.1006-1959.2019.23.052]
[4]曾冬梅.ELISA法和TRUST法在梅毒检测中的应用[J].医学信息,2022,35(17):138.[doi:10.3969/j.issn.1006-1959.2022.17.038]
　ZENG Dong-mei.Application of ELISA and TRUST in Syphilis Detection[J].Medical Information,2022,35(10):138.[doi:10.3969/j.issn.1006-1959.2022.17.038]
[5]王可玲,于艳妮,刘 鹏.梅毒的临床分期特征及其实验室检测方法[J].医学信息,2020,33(06):27.[doi:10.3969/j.issn.1006-1959.2020.06.009]
　PANG Yan-hui,PENG Wei,TAO Wen-jie,et al.Clinical Staging Characteristics of Syphilis and its Laboratory Detection Methods[J].Medical Information,2020,33(10):27.[doi:10.3969/j.issn.1006-1959.2020.06.009]
[6]徐田梅.2011-2020年抚顺市东洲区梅毒病流行病学分析[J].医学信息,2022,35(05):150.[doi:10.3969/j.issn.1006-1959.2022.05.039]
　XU Tian-mei.Epidemiological Analysis of Syphilis in Dongzhou District of Fushun City from 2011 to 2020[J].Medical Information,2022,35(10):150.[doi:10.3969/j.issn.1006-1959.2022.05.039]
[7]陈云梅.梅毒初筛阳性患者对梅毒相关知识的知晓状况及影响因素研究[J].医学信息,2023,36(23):84.[doi:10.3969/j.issn.1006-1959.2023.23.021]
　CHEN Yun-mei.Study on the Awareness of Syphilis-related Knowledge and its Influencing Factors in Patients with Positive Syphilis Screening[J].Medical Information,2023,36(10):84.[doi:10.3969/j.issn.1006-1959.2023.23.021]

更新日期/Last Update: 2020-05-15