[1]文 静,汤展宏.腹腔感染患者感染源控制时机与预后的关系[J].医学信息,2020,33(11):86-90.[doi:10.3969/j.issn.1006-1959.2020.11.025]
　WEN Jing,TANG Zhan-hong.Relationship Between the Timing of Infection Source Control and Prognosis in Patients with Abdominal Infection[J].Medical Information,2020,33(11):86-90.[doi:10.3969/j.issn.1006-1959.2020.11.025]
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腹腔感染患者感染源控制时机与预后的关系()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
33卷
期数:
2020年11期
页码:
86-90
栏目:
综述
出版日期:
2020-06-01

文章信息/Info

Title:
Relationship Between the Timing of Infection Source Control and Prognosis in Patients with Abdominal Infection
文章编号:
1006-1959（2020）11-0086-06
作者:
文 静; 汤展宏
（1.玉林市第一人民医院重症医学科，广西 玉林 537000；2.广西医科大学第一附属医院重症医学科，广西 南宁 530021）
Author(s):
WEN Jing; TANG Zhan-hong
(1.Department of Intensive Medicine,the First People’s Hospital of Yulin City,Yulin 537000,Guangxi,China;2.Department of Intensive Medicine,the First Affiliated Hospital of Guangxi Medical University,Nanning 530021,Guangxi,China)
关键词:
腹腔感染; 感染源; 控制措施; 时机; 预后
Keywords:
Abdominal infection; Source of infection; Control measures; Timing; Prognosis
分类号:
R656
DOI:
10.3969/j.issn.1006-1959.2020.11.025
文献标志码:
A
摘要:
目的 探讨腹腔感染患者采取感染源控制措施的时机对疾病预后的影响。方法 回顾性分析广西医科大学第一附属医院重症医学科二病区2015年7月~2018年12月收治的101例腹腔感染患者的临床资料，根据入院时间或住院期间出现腹腔感染的时间到采取感染源控制措施的时间间隔将患者分成≤6 h组、6~12 h组、12~24 h组、24~48 h组、＞48 h组5组，并将6~12 h组、12~24 h组、24~48 h组及＞48 h组设为＞6 h组，比较各组死亡率、≤6 h组与＞6 h组在住院时间、重症监护室（ICU）监护时间、呼吸机治疗时间、连续性血液净化治疗（CRRT）时间、住院费用及并发症发生情况。结果 患者总体死亡率为34.65%（35/101），≤6 h组死亡率为29.17%，低于6~12 h组（35.71%）、12~24 h组（42.11%）、24~48 h组（33.33%）、＞48 h组（34.62%）4组死亡率，但差异无统计学意义（P＞0.05）。≤6 h组在住院时间、住院费用、腹腔出血的并发症方面优于＞6 h组，差异有统计学意义（P＜0.05）；≤6 h组在肺炎及血流感染的发生率、ICU监护时间、呼吸机治疗时间、CRRT治疗时间均少于＞6 h组，在呼吸衰竭、腹腔脓肿的发生率与＞6 h组相当，在急性肾衰竭、多器官功能障碍综合征（MODS）、肠梗阻、腹腔间隙综合征发生率方面则高于＞6 h组，但差异均无统计学意义（P＞0.05）。结论 在6 h时间窗内尽早采取感染源控制措施并未明显改善腹腔感染患者的不良预后，但在缩短患者的住院时间，减少住院费用，以及减少腹腔出血并发症的发生方面可能具有一定的优势。
Abstract:
Objective To investigate the impact of the timing of infection source control measures on the prognosis of patients with abdominal infection.Methods To retrospectively analyze the clinical data of 101 patients with abdominal infections admitted to the Second Ward of the Department of Critical Medicine of the First Affiliated Hospital of Guangxi Medical University from July 2015 to December 2018. The time interval of source control measures divided the patients into ≤6 h group, 6~12 h group, 12~24 h group, 24~48 h group,＞48 h group 5 groups, and 6~12 h group, 12~24 h group , 24~48 h group and group＞48 h were set as group＞6 h, comparing the mortality in each group, group ≤6 h and group＞6 h in hospital stay, intensive care unit (ICU) monitoring time, ventilator duration of treatment, the duration of continuous blood purification therapy (CRRT), the cost of hospitalization, and the occurrence of complications.Results The overall mortality rate of the patients was 34.65% (35/101), and the mortality rate in the ≤6 h group was 29.17%, lower than the 6-12 h group (35.71%), 12~24 h group (42.11%), 24~48 h group (33.33%),＞48 h group (34.62%) 4 groups mortality, but the difference was not statistically significant (P＞0.05). The ≤6 h group was superior to the ≥6 h group in terms of hospitalization time, hospitalization costs, and complications of abdominal bleeding,the difference was statistically significant (P＜0.05); the ≤6 h group had the incidence of pneumonia and bloodstream infection, ICU Monitoring time, ventilator treatment time, and CRRT treatment time were all less than＞6 h group. The incidence of respiratory failure and abdominal abscess was similar to that of＞6 h group. In acute renal failure, multiple organ dysfunction syndrome (MODS), The incidence of intestinal obstruction and celiac space syndrome was higher than that in the group＞ 6 h, but the difference was not statistically significant (P＞0.05).Conclusion Taking the source control measures as early as possible within the 6 h time window does not significantly improve the poor prognosis of patients with abdominal infections, but may have certain advantages in shortening the hospitalization time of patients, reducing hospitalization costs, and reducing the incidence of abdominal bleeding complications.

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更新日期/Last Update: 1900-01-01