[1]陈慧丽,朱 锋,汪 漩,等.纤维支气管镜下肺泡灌洗辅助治疗呼吸机相关性肺炎的效果[J].医学信息,2020,33(11):107-108.[doi:10.3969/j.issn.1006-1959.2020.11.032]
　CHEN Hui-li,ZHU Feng,WANG Xuan,et al.Effect of Alveolar Lavage Under Fiberoptic Bronchoscope in Treatment of Ventilator-associated Pneumonia[J].Medical Information,2020,33(11):107-108.[doi:10.3969/j.issn.1006-1959.2020.11.032]
点击复制

纤维支气管镜下肺泡灌洗辅助治疗呼吸机相关性肺炎的效果()
分享到：

医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
33卷
期数:
2020年11期
页码:
107-108
栏目:
临床研究
出版日期:
2020-06-01

文章信息/Info

Title:
Effect of Alveolar Lavage Under Fiberoptic Bronchoscope in Treatment of Ventilator-associated Pneumonia
文章编号:
1006-1959（2020）11-0107-02
作者:
陈慧丽; 朱 锋; 汪 漩; 等
（上海市杨浦区中心医院重症医学科，上海 200090）
Author(s):
CHEN Hui-li; ZHU Feng; WANG Xuan; et al
(Department of Intensive Medicine,Central Hospital of Yangpu District,Shanghai 200090,China)
关键词:
纤维支气管镜; 肺泡灌洗; 呼吸机相关性肺炎
Keywords:
Fiberoptic bronchoscopy; Alveolar lavage; Ventilator-associated pneumonia
分类号:
R563.1
DOI:
10.3969/j.issn.1006-1959.2020.11.032
文献标志码:
A
摘要:
目的 探讨纤维支气管镜下肺泡灌洗辅助治疗呼吸机相关性肺炎的临床疗效。方法 选取2017年4月~2019年8月我院收治的呼吸机相关性肺炎患者102例作为研究对象，采用随机数字表法分为对照组和观察组，每组51例。对照组行常规治疗，观察组在对照组基础上行纤维支气管镜下肺泡灌洗辅助治疗，比较两组治疗效果、炎性因子水平[C-反应蛋白（CRP）、白介素-8（IL-8）]。结果 观察组治疗总有效率为96.08%，高于对照组的82.35%，差异有统计学意义（P＜0.05）；治疗后，两组CRP、IL-8水平均较治疗前降低，且观察组低于对照组，差异有统计学意义（P＜0.05）。结论 经纤维支气管镜下肺泡灌洗辅助治疗呼吸机相关性肺炎临床效果确切，可有效降低患者炎性因子水平，改善炎性反应，促进患者病情恢复。
Abstract:
Objective To explore the clinical efficacy of fiberoptic bronchoscopic alveolar lavage in the adjuvant treatment of ventilator-associated pneumonia.Methods A total of 102 patients with ventilator-associated pneumonia admitted in our hospital from April 2017 to August 2019 were selected as the research object, using the random number table method to divided into control group and observation group, with 51 cases in each group. The control group received routine treatment, and the observation group underwent adjuvant alveolar lavage under the control of the bronchofibroscope, compare the treatment effect and inflammatory factor level [C-reactive protein (CRP), interleukin-8 (IL-8)] changes between the two groups.Results The total effective rate of treatment in the observation group was 96.08%, higher than 82.35% that in the control group, the difference was statistically significant(P<0.05); After treatment, the levels of CRP and IL-8 in the two groups were lower than before treatment, and the observation group was lower than the control group, the difference was statistically significant(P<0.05).Conclusion The alveolar lavage under fiberoptic bronchoscopy has a definite clinical effect on the treatment of ventilator-associated pneumonia. It can effectively reduce the level of inflammatory factors, improve the inflammatory response, and promote the recovery of the patient’s condition.

参考文献/References:

[1]唐毓宜,韦庆,韦真.纤维支气管镜下肺泡灌洗辅助治疗呼吸机相关性肺炎的效果[J].临床医学研究与实践,2019,4(29):67-69.[2]陈海玉,曾广志,唐召力,等.纤维支气管镜肺泡灌洗术治疗重症肺炎对患者全身炎症反应、呼吸力学指标的影响[J].中国医师杂志,2019,21(8):1251-1253.[3]穆冠玉.纤维支气管镜下肺泡灌洗辅助治疗呼吸机相关性肺炎患者效果观察[J].临床医药文献电子杂志,2019,6(45):50.[4]雷莉莉,韩智云,王瑛.支气管肺泡灌洗治疗呼吸机相关性肺炎患者疗效分析[J].内科,2019,11(3):300-302.[5]周立,程旭东,严蕊娜,等.支气管镜下肺泡灌洗对难治性肺炎患者炎症介质和肺功能的影响[J].现代生物医学进展,2017,17(23):4549-4551.

相似文献/References:

[1]阳池娇,陈进喜,林业辉,等.肺炎支原体肺炎患儿血清及肺泡灌洗液MIF水平与气道黏液栓的关系探讨[J].医学信息,2022,35(17):82.[doi:10.3969/j.issn.1006-1959.2022.17.021]
　YANG Chi-Jiao,CHEN Jin-xi,LIN Ye-hui,et al.Study on the Relationship Between the MIF levels of Serum and Bronchoalveolar Lavage Fluid and Airway Mucus Plug in Children with Mycoplasma Pneumoniae Pneumonia[J].Medical Information,2022,35(11):82.[doi:10.3969/j.issn.1006-1959.2022.17.021]
[2]李洪燕,林业辉,陈进喜,等.儿童塑型性支气管炎的临床特征分析[J].医学信息,2020,33(15):76.[doi:10.3969/j.issn.1006-1959.2020.15.024]
　LI Hong-yan,LIN Ye-hui,CHEN Jin-xi,et al.Analysis of Clinical Features of Children’s Plastic Bronchitis[J].Medical Information,2020,33(11):76.[doi:10.3969/j.issn.1006-1959.2020.15.024]
[3]黄永辉,吕 刚.纤维支气管镜下注入依替米星治疗脑卒中后肺炎的疗效[J].医学信息,2020,33(15):146.[doi:10.3969/j.issn.1006-1959.2020.15.046]
　HUANG Yong-hui,LYU Gang.Efficacy of Injecting Etimicin under Fiberoptic Bronchoscopein the Treatment of Pneumonia After Stroke[J].Medical Information,2020,33(11):146.[doi:10.3969/j.issn.1006-1959.2020.15.046]
[4]郑合清.盐酸氨溴索联合纤维支气管镜吸痰对老年肺炎的疗效及安全性[J].医学信息,2021,34(14):154.[doi:10.3969/j.issn.1006-1959.2021.14.043]
　ZHENG He-qing.Efficacy and Safety of Ambroxol Hydrochloride Combined with Fiberoptic Bronchoscopy for Sputum Suction in Elderly Patients with Pneumonia[J].Medical Information,2021,34(11):154.[doi:10.3969/j.issn.1006-1959.2021.14.043]
[5]范素芳,孟宪坤,赵桂金.儿童呼吸系统疾病的诊治现状[J].医学信息,2022,35(05):49.[doi:10.3969/j.issn.1006-1959.2022.05.012]
　FAN Su-fang,MENG Xian-kun,ZHAO Gui-jin.Diagnosis and Treatment of Respiratory Diseases in Children[J].Medical Information,2022,35(11):49.[doi:10.3969/j.issn.1006-1959.2022.05.012]
[6]雷文明.纤维支气管镜吸痰灌洗治疗呼吸重症监护室肺部感染的临床研究[J].医学信息,2022,35(06):129.[doi:10.3969/j.issn.1006-1959.2022.06.032]
　LEI Wen-ming.Clinical Study on the Treatment of Pulmonary Infection in Respiratory Intensive Care Unit by Suctioning and Lavage with Fiberoptic Bronchoscopy[J].Medical Information,2022,35(11):129.[doi:10.3969/j.issn.1006-1959.2022.06.032]
[7]袁 博.纤维支气管镜下肺泡灌洗对呼吸机相关性肺炎患者感染控制及呼吸功能的影响[J].医学信息,2020,33(22):117.[doi:10.3969/j.issn.1006-1959.2020.22.033]
　YUAN Bo.Effect of Alveolar Lavage under Fiberoptic Bronchoscope on Infection Control and Respiratory Function in Patients with Ventilator-associated Pneumonia[J].Medical Information,2020,33(11):117.[doi:10.3969/j.issn.1006-1959.2020.22.033]

更新日期/Last Update: 1900-01-01