[1]钟 焜,朱西琪.脑小血管病影像特征及其与认知功能的关系[J].医学信息,2020,33(17):27-29.[doi:10.3969/j.issn.1006-1959.2020.17.008]
 ZHONG Kun,ZHU Xi-qi.The Imaging Features of Cerebral Small Vessel Disease and Its Relationship with Cognitive Function[J].Medical Information,2020,33(17):27-29.[doi:10.3969/j.issn.1006-1959.2020.17.008]
点击复制

脑小血管病影像特征及其与认知功能的关系()
分享到:

医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
33卷
期数:
2020年17期
页码:
27-29
栏目:
综述
出版日期:
2020-09-01

文章信息/Info

Title:
The Imaging Features of Cerebral Small Vessel Disease and Its Relationship with Cognitive Function
文章编号:
1006-1959(2020)17-0027-03
作者:
钟 焜朱西琪
(1.桂林医学院,广西 桂林 541004;2.广西壮族自治区南溪山医院影像科,广西 桂林 541002)
Author(s):
ZHONG KunZHU Xi-qi
(1.Guilin Medical College,Guilin 541004,Guangxi,China;2.Department of Imaging,Nanxishan Hospital,Guangxi Zhuang Autonomous Region,Guilin 541002, Guangxi,China)
关键词:
脑小血管病认知功能神经影像
Keywords:
Cerebral small vessel diseaseCognitive functionNeuroimaging
分类号:
R743
DOI:
10.3969/j.issn.1006-1959.2020.17.008
文献标志码:
A
摘要:
脑小血管病(CSVD)是由脑小动脉、微动脉、小静脉和毛细血管病变导致的临床、病理和影像学综合征,临床表现存在静寂现象,发病隐匿而不易识别。随着影像学技术的发展,CSVD的检出率逐年提高,影像学主要表现为近期皮质下梗死、血管源性腔隙、血管起源的白质高信号、血管周围间隙扩大、脑微出血以及脑萎缩等特征。研究表明,CSVD可导致注意力、执行功能、信息加工速度、视空间等认知功能损害,甚至诱发痴呆。本文就CSVD的神经影像学特征及其与认知功能的关系作一综述,旨在为临床治疗提供参考。
Abstract:
Cerebral small vessel disease (CSVD) is a clinical, pathological and imaging syndrome caused by cerebral arterioles, arterioles, venules, and capillaries. The clinical manifestations are silent, and the onset is hidden and difficult to identify. With the development of imaging technology, the detection rate of CSVD is increasing year by year. Imaging mainly manifests as recent subcortical infarction, vascular-derived lacuna, vascular-derived white matter hyperintensity, perivascular space expansion, cerebral microhemorrhage, and brain atrophy and other features. Studies have shown that CSVD can cause damage to cognitive functions such as attention, executive function, information processing speed, visual space, and even induce dementia. This article reviews the neuroimaging characteristics of CSVD and its relationship with cognitive function, aiming to provide reference for clinical treatment.

参考文献/References:

[1]Lee KJ,Jung H,Oh YS,et al.The Fate of Acute Lacunar Lesions in Terms of Shape and Size[J].Journal of Stroke and Cerebrovascular Diseases,2017,26(6):1254-1257.[2]Kwon HS,Cho AH,Lee MH,et al.Evolution of acute lacunar lesions in terms of size and shape: a PICASSO sub-study[J].Journal of Neurology,2019,266(3):766-772.[3]Wong SM,Jansen JFA,Zhang CE,et al.Blood-brain barrier impairment and hypoperfusion are linked in cerebral small vessel disease[J].Neurology,2019,92(15):1669-1677.[4]Potter GM,Chappell FM,Morris Z,et al.Cerebral Perivascular Spaces Visible on Magnetic Resonance Imaging:Development of a Qualitative Rating Scale and its Observer Reliability[J].Cerebrovascular Diseases,2015,39(3-4):224-231.[5]Potter GM,Doubal FN,Jackson CA,et al.Enlarged perivascular spaces and cerebral small vessel disease[J].Int J Stroke,2015,10(3):376-381.[6]Groeschel S,Chong WK,Surtees R,et al.Virchow-Robin spaces on magnetic resonance images:normative data,their dilatation,and a review of the literature[J].Neuroradiology,2006,48(10):745-754.[7]Shao L,Wang M,Ge XH,et al.The use of susceptibility-weighted imaging to detect cerebral microbleeds after lacunar infarction[J].European Review for Medical&Pharmacological Sciences,2017,21(13):3105-3112.[8]Song J,Kim OJ,Kim HS,et al.Endothelial nitric oxide synthase gene polymorphisms and the risk of silent brain infarction[J].International Journal of Molecular Medicine,2010,25(5):819-823.[9]姜季委,王继蕊,李娇,等.额叶皮质微小梗死灶所致偏侧舞蹈症一例[J].中华神经科杂志,2018,51(4):299-301.[10]Carey CL,Kramer JH,Josephson S A,et al.Subcortical Lacunes Are Associated With Executive Dysfunction in Cognitively Normal Elderly[J].Stroke,2008,39(2):397-402.[11]Albert M,Zhu Y,Moghekar A,et al.Predicting progression from normal cognition to mild cognitive impairment for individuals at 5 years[J].Brain,2018,141(3):877-887.[12]Divya KP,Menon RN,Varma RP,et al.Post-stroke cognitive impairment-A cross-sectional comparison study between mild cognitive impairment of vascular and non-vascular etiology[J].Journal of the Neurological Sciences,2016(372):356-362.[13]Bangen KJ,Preis SR,Delano-Wood L,et al.Baseline White Matter Hyperintensities and Hippocampal Volume are Associated With Conversion From Normal Cognition to Mild Cognitive Impairment in the Framingham Offspring Study[J].Alzheimer Disease and Associated Disorders,2018,32(1):50-56.[14]Kohara K,Okada Y,Ochi M,et al.Muscle mass decline,arterial stiffness,white matter hyperintensity,and cognitive impairment:Japan Shimanami Health Promoting Program study[J].Journal of Cachexia,Sarcopenia and Muscle,2017,8(4):557-566.[15]Tuladhar AM,Reid AT,Shumskaya E,et al.Relationship Between White Matter Hyperintensities,Cortical Thickness,and Cognition[J].Stroke,2015,46(2):425-432.[16]Saima H,Seng TC,Adams HHH,et al.Enlarged perivascular spaces and cognition[J].Neurology,2018,91(9):832-842.[17]Akoudad S,Wolters FJ,Viswanathan A,et al.Association of Cerebral Microbleeds With Cognitive Decline and Dementia[J].JAMA Neurology,2016,73(8):934-943.[18]Brundel M,Kwa VIH,Bouvy WH,et al.Cerebral Microbleeds Are Not Associated with Long-Term Cognitive Outcome in Patients with Transient Ischemic Attack or Minor Stroke[J].Cerebrovascular Diseases,2014,37(3):195-202.[19]Uiterwijk R,Huijts M,Staals J,et al.Subjective Cognitive Failures in Patients With Hypertension Are Related to Cognitive Performance and Cerebral Microbleeds[J].Hypertension,2014,64(3):653-657.[20]杨洁,区腾飞,蒲蜀湘,等.卒中及短暂性脑缺血发作患者不同部位脑萎缩的危险因素[J].中国神经精神疾病杂志,2016,42(10):609-615.[21]Kim GH,Lee JH,Seo SW,et al.Hippocampal volume and shape in pure subcortical vascular dementia[J].Neurobiol Aging,2015,36(1):485-491.[22]童宣霞,王龙,周霞,等.脑萎缩对皮质下缺血性血管病患者认知功能的影响[J].中华医学杂志,2016,96(1):14-19.

相似文献/References:

[1]王 丹,谢婷婷,张 莉.七氟醚与丙泊酚静脉麻醉对老年髋关节置换术患者 认知功能的影响[J].医学信息,2018,31(09):133.[doi:10.3969/j.issn.1006-1959.2018.09.041]
 WANG Dan,XIE Ting-ting,ZHANG Li.Effects of Sevoflurane and Propofol Intravenous Anesthesia on Cognitive Function in Elderly Patients Undergoing Hip Replacement[J].Medical Information,2018,31(17):133.[doi:10.3969/j.issn.1006-1959.2018.09.041]
[2]韩 倩,刘 兴.脑小血管病诊疗进展[J].医学信息,2018,31(11):52.[doi:10.3969/j.issn.1006-1959.2018.11.017]
 HAN Qian,LIU Xing.Progress in Diagnosis and Treatment of Small Cerebral Vascular Disease[J].Medical Information,2018,31(17):52.[doi:10.3969/j.issn.1006-1959.2018.11.017]
[3]袁志国,朱 玫,魏晓佳,等.联合胸神经阻滞应用于老年胸腔镜肺叶切除术后的效果及对认知功能的影响[J].医学信息,2022,35(11):102.[doi:10.3969/j.issn.1006-1959.2022.11.026]
 YUAN Zhi-guo,ZHU Mei,WEI Xiao-jia,et al.Effect of Combined Thoracic Nerve Block on Cognitive Function After Thoracoscopic Lobectomy in Elderly Patients[J].Medical Information,2022,35(17):102.[doi:10.3969/j.issn.1006-1959.2022.11.026]
[4]包娜娜,刘 超.太极拳对遗忘型轻度认知功能障碍患者认知功能影响的研究[J].医学信息,2019,32(02):115.[doi:10.3969/j.issn.1006-1959.2019.02.032]
 BAO Na-na,LIU Chao.Study on Taijiquan in Patients with Amnestic Mild Cognitive Dysfunction[J].Medical Information,2019,32(17):115.[doi:10.3969/j.issn.1006-1959.2019.02.032]
[5]胡金艳,王 冬.影响老年糖尿病患者发生认知障碍的危险因素分析[J].医学信息,2018,31(16):55.[doi:10.3969/j.issn.1006-1959.2018.16.015]
 HU Jin-yan,WANG Dong.Analysis of Risk Factors Affecting Cognitive Impairment in Elderly Diabetic Patients[J].Medical Information,2018,31(17):55.[doi:10.3969/j.issn.1006-1959.2018.16.015]
[6]蒙新宇.显微镜外科手术治疗脑胶质瘤的近期疗效及对患者认知功能的影响[J].医学信息,2022,35(12):146.[doi:10.3969/j.issn.1006-1959.2022.12.035]
 MENG Xin-yu.Effect of Microsurgery on Cognitive Function in Patients with Brain Glioma[J].Medical Information,2022,35(17):146.[doi:10.3969/j.issn.1006-1959.2022.12.035]
[7]杨彩霞.慢性精神分裂症患者庇护性就业训练的疗效观察[J].医学信息,2019,32(06):120.[doi:10.3969/j.issn.1006-1959.2019.06.037]
 YANG Cai-xia.Therapeutic Effect of Sheltered Employment Training for Patients with Chronic Schizophrenia[J].Medical Information,2019,32(17):120.[doi:10.3969/j.issn.1006-1959.2019.06.037]
[8]张 辉,张 颖.多奈哌齐联合司来吉兰对阿尔茨海默病患者认知功能及不良反应的影响[J].医学信息,2022,35(13):110.[doi:10.3969/j.issn.1006-1959.2022.13.024]
 ZHANG Hui,ZHANG Ying.Effect of Donepezil Combined with Selegilan on Cognitive Function and Adverse Reactions in Patients with Alzheimer’s Disease[J].Medical Information,2022,35(17):110.[doi:10.3969/j.issn.1006-1959.2022.13.024]
[9]袁秀萍.高压氧联合尼莫地平治疗脑小血管病所致 认知功能障碍的疗效评价[J].医学信息,2019,32(17):79.[doi:10.3969/j.issn.1006-1959.2019.17.024]
 YUAN Xiu-ping.Efficacy Evaluation of Hyperbaric Oxygen Combined with Nimodipine in the Treatment of Cognitive Dysfunction Caused by Cerebral Small Vessel Disease[J].Medical Information,2019,32(17):79.[doi:10.3969/j.issn.1006-1959.2019.17.024]
[10]曲艳津.益肾填精法对慢性脑供血不足患者脑动力学的影响[J].医学信息,2019,32(19):160.[doi:10.3969/j.issn.1006-1959.2019.19.053]
 QU Yan-jin.Effect of Yishen Filling Method on Brain Dynamics in Patients with Chronic Cerebral Insufficiency[J].Medical Information,2019,32(17):160.[doi:10.3969/j.issn.1006-1959.2019.19.053]
[11]姚慧霞,郭红菊,栾晓倩,等.脑小血管病患者心率变异性与认知功能的相关性[J].医学信息,2023,36(18):110.[doi:10.3969/j.issn.1006-1959.2023.18.020]
 YAO Hui-xia,GUO Hong-ju,LUAN Xiao-qian,et al.Correlation Between Heart Rate Variability and Cognitive Function in Patients with Cerebral Small Vessel Disease[J].Medical Information,2023,36(17):110.[doi:10.3969/j.issn.1006-1959.2023.18.020]

更新日期/Last Update: 1900-01-01