[1]褚 锋,杨侃侃,李启信.青年结直肠癌患者的临床病理特征及预后分析[J].医学信息,2021,34(02):5-7.[doi:10.3969/j.issn.1006-1959.2021.02.002]
 CHU Feng,YANG Kan-kan,LI Qi-xin.Clinicopathological Characteristics and Prognosis Analysis of Young Patients with Colorectal Cancer[J].Medical Information,2021,34(02):5-7.[doi:10.3969/j.issn.1006-1959.2021.02.002]
点击复制

青年结直肠癌患者的临床病理特征及预后分析()
分享到:

医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
34卷
期数:
2021年02期
页码:
5-7
栏目:
出版日期:
2021-01-15

文章信息/Info

Title:
Clinicopathological Characteristics and Prognosis Analysis of Young Patients with Colorectal Cancer
文章编号:
1006-1959(2021)02-0005-03
作者:
褚 锋杨侃侃李启信
(安徽医科大学附属巢湖医院胃肠外科,安徽 巢湖 238000)
Author(s):
CHU FengYANG Kan-kanLI Qi-xin
(Department of Gastrointestinal Surgery,Chaohu Hospital Affiliated to Anhui Medical University,Chaohu 238000,Anhui,China)
关键词:
青年结直肠癌病理特点预后分析
Keywords:
Young colorectal cancerPathological characteristicsPrognostic analysis
分类号:
R735.3
DOI:
10.3969/j.issn.1006-1959.2021.02.002
文献标志码:
A
摘要:
目的 探讨青年结直肠癌患者的临床病理特征及其与预后的相关性。方法 收集并整理2005年1月~2014年12月于我院治疗的65例青年结直肠癌患者的临床病理资料,回顾性分析其临床病理特点及预后情况,分析各项临床病理指标对患者预后的影响。结果 单因素分析结果显示,患者的预后与肿瘤T分期、N分期、TNM分期、肿瘤分化程度、有无脉管癌栓、有无侵犯神经及手术方式有关(P<0.05);COX回归分析显示,青年结直肠癌患者预后的独立影响因素为T分期、TNM分期及有无侵犯神经(P<0.05)。结论 T分期、TNM分期和神经浸润是影响青年结直肠癌患者预后的独立因素,早发现、早诊断、早治疗是改善青年结直肠癌预后的关键措施。
Abstract:
Objective To explore the clinicopathological characteristics of young patients with colorectal cancer and their correlation with prognosis.Methods The clinicopathological data of 65 young patients with colorectal cancer treated in our hospital from January 2005 to December 2014 were collected and sorted. The clinicopathological characteristics and prognosis of the patients were retrospectively analyzed. The prognosis of the patients was analyzed by various clinicopathological indicators.Results Univariate analysis showed that the patient’s prognosis was related to tumor T stage, N stage, TNM stage, tumor differentiation, presence or absence of vascular tumor thrombus, presence or absence of nerve invasion, and surgical methods (P<0.05); COX regression analysis showed,the independent factors affecting the prognosis of young patients with colorectal cancer were T stage, TNM stage and the presence or absence of nerve invasion(P<0.05).Conclusion T staging, TNM staging and nerve invasion are independent factors affecting the prognosis of young patients with colorectal cancer. Early detection, early diagnosis and early treatment are key measures to improve the prognosis of young patients with colorectal cancer.

参考文献/References:

[1]Chen W,Zheng R,Baade PD,et al.Cancer statistics in China,2015[J].CA Cancer J Clin,2016,66(2):115-132. [2]Feng RM,Zong YN,Cao SM,et al.Current cancer situation in China: good or bad news from the 2018 Global Cancer Statistics[J].Cancer Commun(Lond),2019,39(1):22. [3]Hadjipetrou A,Anyfantakis D,Galanakis CG,et al.Colorectal cancer,screening and primary care:A mini literature review[J].World J Gastroenterol,2017,23(33):6049-6058. [4]Douaiher J,Ravipati A,Grams B,et al.Colorectal cancer-global burden, trends,and geographical variations[J].J Surg Oncol,2017,115(5):619-630. [5]You YN,Xing Y,Feig BW,et al.Young-onset colorectal cancer:is it time to pay attention[J].Arch Intern Med,2012,172(3):287-289. [6]Yuan Y,Li MD,Hu HG,et al.Prognostic and survival analysis of 837 Chinese colorectal cancer patients[J].World J Gastroenterol,2013,19(17):2650-2659. [7]WHO.Global Accelerated Action for the Health of Adolescents(AA-HA):guidance to support country implementation[J].Geneva,2017(6). [8]冯雅靖,王宁,方利文,等.1990年与2013年中国人群结直肠癌疾病负担分析[J].中华流行病学杂志,2016,37(6):768-772. [9]Zhao P,Dai M,Chen W,Li N.Cancer trends in China[J].Jpn J Clin Oncol,2010,40(4):281-285. [10]李道娟,李倩,贺宇彤.结直肠癌流行病学趋势[J].肿瘤防治研究,2015,42(3):305-310. [11]Kolarich A,George TJJ,Hughes SJ,et al.Rectal cancer patients younger than 50 years lack a survival benefit from NCCN guideline-directed treatment for stage II and III disease[J].Cancer,2018,124(17):3510-3519. [12]Abdelsattar ZM,Wong SL,Regenbogen SE,et al.Colorectal cancer outcomes and treatment patterns in patients too young for average-risk screening[J].Cancer,2016,122(6):929-934. [13]Wang MJ,Ping J,Li Y,et al.The prognostic factors and multiple biomarkers in young patients with colorectal cancer[J].Sci Rep,2015(5):10645. [14]Zaborowski AM,Murphy B,Creavin B,et al.Clinicopathological features and oncological outcomes of patients with young-onset rectal cancer[J].Br J Surg,2020,107(5):606-612. [15]吴泽华,邓艳红.结直肠癌流行病学东西方差异对肿瘤部位的影响[J].中国癌症防治杂志,2017,9(5):356-360. [16]Benedix F,Kube R,Meyer F,et al.Comparison of 17,641 patients with right-and left-sided colon cancer:differences in epidemiology,perioperative course,histology,and survival[J].Dis Colon Rectum,2010,53(1):57-64. [17]Meguid RA,Slidell MB,Wolfgang CL,et al.Is There a Difference in Survival Between Right- Versus Left-Sided Colon Cancers[J].Ann Surg Oncol,2008,15(9). [18]Feng Z,Shi X,Zhang Q,et al.Analysis of clinicopathological features and prognosis of 1315 cases in colorectal cancer located at different anatomical subsites[J].Pathol Res Pract,2019,215(10):152560.

相似文献/References:

[1]李 磊.儿童强直性肌营养不良3例临床、电生理及病理特点[J].医学信息,2018,31(13):190.[doi:10.3969/j.issn.1006-1959.2018.13.061]
 LI Lei.Clinical,Electrophysiological and Pathological Characteristics of 3 Cases of Children with Myotoruc Dystrophy[J].Medical Information,2018,31(02):190.[doi:10.3969/j.issn.1006-1959.2018.13.061]
[2]石小红,姜 彦,王 琳.头颈部小圆细胞恶性肿瘤临床特点分析[J].医学信息,2019,32(05):142.[doi:10.3969/j.issn.1006-1959.2019.05.045]
 SHI Xiao-hong,JIANG Yan,WANG Lin.Clinical Characteristics of Small Round Cell Malignant Tumors of the Head and Neck[J].Medical Information,2019,32(02):142.[doi:10.3969/j.issn.1006-1959.2019.05.045]
[3]黄 婷,张亚莉,李 燕,等.不同性别IgA肾病患者相关临床指标及病理特点对比[J].医学信息,2019,32(21):125.[doi:10.3969/j.issn.1006-1959.2019.21.040]
 HUANG Ting,ZHANG Ya-li,LI Yan,et al.Comparative Analysis of Clinical and Pathological Features of Patients with Different Sex IgA Nephropathy[J].Medical Information,2019,32(02):125.[doi:10.3969/j.issn.1006-1959.2019.21.040]

更新日期/Last Update: 1900-01-01