[1]张 伟,王 莉,朱生东,等.2014~2018年我院不完全川崎病诊断及临床特点分析[J].医学信息,2021,34(02):149-151.[doi:10.3969/j.issn.1006-1959.2021.02.041]
　ZHANG Wei,WANG Li,ZHU Sheng-dong,et al.Analysis of Incomplete Kawasaki Disease Diagnosis and Clinical Characteristics in Our Hospital from 2014 to 2018[J].Medical Information,2021,34(02):149-151.[doi:10.3969/j.issn.1006-1959.2021.02.041]
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2014~2018年我院不完全川崎病诊断及临床特点分析()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
34卷
期数:
2021年02期
页码:
149-151
栏目:
调查分析
出版日期:
2021-01-15

文章信息/Info

Title:
Analysis of Incomplete Kawasaki Disease Diagnosis and Clinical Characteristics in Our Hospital from 2014 to 2018
文章编号:
1006-1959（2021）02-0149-03
作者:
张 伟; 王 莉; 朱生东; 等
（甘肃省妇幼保健院小儿综合内科，甘肃 兰州 730050）
Author(s):
ZHANG Wei; WANG Li; ZHU Sheng-dong; et al.
(Department of Pediatric Comprehensive Internal Medicine,Gansu Provincial Maternal and Child Health Hospital, Lanzhou 730050,Gansu,China)
关键词:
不完全川崎病; 临床特点; 发热
Keywords:
Incomplete Kawasaki disease; Clinical features; Fever
分类号:
R729
DOI:
10.3969/j.issn.1006-1959.2021.02.041
文献标志码:
A
摘要:
目的 调查2014~2018年我院不完全川崎病确诊情况，进一步分析患者的临床资料、实验室检查结果及误诊情况。方法 回顾性分析2014年1月~2018年12月甘肃省妇幼保健院不完全川崎病诊断情况（10天内确诊），评估误诊率，收集确诊患者的临床表现及实验室检查结果。结果 2014~2016年我院不完全川崎病诊断例数较少，最高仅为23.07%，且误诊率较高；2017~2018年该院确诊率最高达85.71%；不完全川崎病主要临床表现有发热、结膜非渗出性充血、口唇潮红、卡介苗接种处红斑、多形性皮疹、甲床移行处膜状脱皮及淋巴结肿大；次要临床表现以易激惹、烦躁及消化系统症状为主；实验室指标以C-反应蛋白升高最为常见，其次还包括血沉、白细胞计数升高。结论 2014~2016年该院不完全川崎病误诊率较高，2017年后有较大改善。另外，该病主要表现以发热为主，应充分认识其临床特征，尽早行相关实验室检查，做到早诊断、早治疗。
Abstract:
Objective To investigate the incomplete diagnosis of Kawasaki disease in our hospital from 2014 to 2018, and to further analyze the clinical data, laboratory test results and misdiagnosis of patients.Methods A retrospective analysis of the incomplete diagnosis of Kawasaki disease in Gansu Maternity and Child Health Hospital from January 2014 to December 2018 (diagnosed within 10 days) was performed to assess the misdiagnosis rate, and collect the clinical manifestations and laboratory test results of confirmed patients.Results The number of diagnosed cases of incomplete Kawasaki disease in this hospital from 2014 to 2016 was small, the highest was only 23.07%, and the misdiagnosis rate was high; from 2017 to 2018, the highest diagnosis rate in this hospital was 85.71%;The main clinical manifestations of incomplete Kawasaki disease include fever, non-exudative conjunctival hyperemia, lip flushing, erythema at the BCG vaccination site, polymorphic skin rash, membranous peeling at the transition of the nail bed, and lymphadenopathy; secondary clinical manifestations are irritable,Irritability and digestive system symptoms; the most common laboratory indicators are elevated C-reactive protein, followed by elevated erythrocyte sedimentation rate and white blood cell count.Conclusion The misdiagnosis rate of incomplete Kawasaki disease was high in this hospital from 2014 to 2016, and it has improved significantly after 2017. In addition, the main manifestation of the disease is fever, and its clinical features should be fully understood, and relevant laboratory tests should be performed as soon as possible to achieve early diagnosis and early treatment.

参考文献/References:

[1]Tamaki W,Tsuda E,Takehiro I,et al.Importance of evaluation of the right coronary artery by two-dimensional echocardiography in patients after Kawasaki disease: a right parasternal approach[J].Heart Vessels,2015,30(2):178-185. [2]黄坤美,吴永忠,赖伟权,等.川崎病患儿急性期血浆脑 利钠肽、D-二聚体、 纤维蛋白原水平变化与临床观察[J].实用医学杂志,2015,31(12):2001-2003. [3]何跃娥,诸凤,李萍,等.氧化型低密度脂蛋白在早期预 测川崎病冠状动脉损害中的价值[J].中华风湿病学杂志,2017,21(7):439-443. [4]Gravel H,Curnier D,Davaire F,et al.Cardiovascular Response to Exercise Testing in Children and Adolescents Late After Kawasaki Disease According to Coronary Condition Upon Onse[J].Pediatric Cardiology,2015,36(7):1458-1464. [5]杜忠东,陈笑征.川崎病流行病学研究进展[J].中国实用儿科杂志,2017,32(8):565-569. [6]Agarwal S,Agrawal Dk.Kawasaki disease:etiopatho- genesis and novel treatment strategies [J].Expert Rev Clin Immunol,2017,13(3):247-258. [7]刘丁,杨方.典型川崎病与不完全川崎病的临床特点单中心比较分析[J].临床荟萃,2018,33(3):236-239. [8]谢添.川崎病的治疗与随访[J].国际儿科学杂志,2017,44(11):163-167. [9]Turkay S,Odemis E,Karadag A.Kawasaki disease onset during concomitant infections with varicella zoster and Epstein- Barr virus[J].J Natl Med Assoc,2016,98(12):1350-1352. [10]Sonobe T,Kiyosawa N,Tsuchiya K,et al.Prevalence of coronary artery abnormality in incomplete Kawasaki disease[J].Pediatr Int,2017,49(4):421-426. [11]张清友,杜保军.不完全川崎病的诊治现状[J].中华儿科杂志,2006,44(5):339. [12]Nakamura Y,Yashiro M,Uehara R,et al.Epidemiologic features of Kawasaki disease in Japan: results of the 2009-2010 nationwide survey[J].J Epidemiol,2012,22(3):216-221. [13]Huang GY,Ma XJ,Huang M,et al.Epidemiologic Pictures of Kawasaki disease in Shanghai from 1998 through 2002[J].Journal of Epidemiology,2006,16(1):9. [14]谢利剑,马晓静,俞岑妍,等.不同IVIG治疗方案对川崎病冠状动脉病变影响的多中心回顾性研究[J].临床儿科杂志,2010,28(7):624-627. [15]徐灵敏,李彦晓,孙琪青,等.AHA推荐的8项不完全川崎病实验室诊断指标临床意义探讨[J].中国实用儿科杂志,2012,27(2):142-144.

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更新日期/Last Update: 1900-01-01