参考文献/References:
[1]Pietrini P,Furey ML.The role of the cholinergic system in physiological and pathological conditions[J].International Journal of Psychophysiology,2008,69(3):187-187. [2]Semenza GL,Wang GL.A nuclear factor induced by hypoxia via de novo protein synthesis binds to the human erythropoietin gene enhancer at a site required for transcriptional activation[J].Molecular&Cellular Biology,1992(12):5447-5454. [3]Akanji MA,Rotimi D,Adeyemi OS.Hypoxia-Inducible Factors as an Alternative Source of Treatment Strategy for Cancer[J].Oxidative Medicine and Cellular Longevity,2019(2019):1-10. [4]Diers AR,Vayalil PK,Oliva CR,et al.Mitochondrial Bioenergetics of Metastatic Breast Cancer Cells in Response to Dynamic Changes in Oxygen Tension:Effects of HIF-1α[J].PLoS One,2013,8(6):e68348. [5]Gan L,Meng J,Xu M,et al.Extracellular matrix protein 1 promotes cell metastasis and glucose metabolism by inducing integrin β4/FAK/SOX2/HIF-1α signaling pathway in gastric cancer[J].Oncogene,2018,37(6):744-755. [6]叶飞轮.瘢痕疙瘩中HIF-1α的表达及其与血管新生、炎症反应及细胞凋亡的相关性研究[J].海南医学院学报,2017(23):2442-2444,2448. [7]Palazon A,Goldrath A,Nizet V,et al.HIF Transcription Factors, Inflammation, and Immunity[J].Immunity,2014,41(4):518-528. [8]Thirlwell C,Schulz L,Dibra H,et al.Suffocating cancer:hypoxia-associated epimutations as targets for cancer therapy[J].Clinical Epigenetics,2011,3(1):9. [9]Bala A,Roberta O,Russell C,et al.Analysis of Wound Care Assessment Tools Used by Phyiscal Therapists to Document Wound Healing Progress[J].Archives of Physical Medicine and Rehabilitation,2019,100(12):e167. [10]He X,Ding Y,Duan S,et al.Wound Dressings Based on Rubidium-Doped Bioactive Glass Nanospheres Promote Diabetic Wound Healing[J].Journal of Biomedical Nanotechnology,2019,15(10):2059-2071. [11]Xing D,Liu L,Marti GP,et al.Hypoxia and hypoxia‐inducible factor in the burn wound[J].Wound Repair and Regeneration,2011,19(2):205-213. [12]龚若文,吴克玲,左成果,等.缺氧诱导因子-1在兔结膜伤口愈合模型的表达[J].中山大学学报(医学版),2018(39):827-834,872. [13]Sunkari VG,Lind F,Botusan IR,et al.Hyperbaric oxygen therapy activates hypoxia-inducible factor 1(HIF-1),which contributes to improved wound healing in diabetic mice[J].Wound Repair and Regeneration,2015,23(1):98-103. [14]Duscher D,Maan ZN,Whittam AJ,et al.Fibroblast-Specific Deletion of Hypoxia Inducible Factor-1 Critically Impairs Murine Cutaneous Neovascularization and Wound Healing[J].Plastic &Reconstructive Surgery,2015,136(5):1004-1013. [15]Hong L,Xun Z,Liang C,et al.Negative pressure wound therapy promotes muscle-derived stem cell osteogenic differentiation through MAPK pathway[J].Journal of Cellular and Molecular Medicine,2019,22(1):511-520. [16]Zhou BY,Wang WB,Wu XL,et al.Nintedanib inhibits keloid fibroblast functions by blocking the phosphorylation of multiple kinases and enhancing receptor internalization[J].Acta Pharmacologica Sinica,2020,41(9):1234-1245. [17]Nagaraja S,Chen L,Zhou J,et al.Predictive Analysis of Mechanistic Triggers and Mitigation Strategies for Pathological Scarring in Skin Wounds[J].Journal of Immunology,2017,198(2):832. [18]Sideek MA,Teia A,Kopecki Z,et al.Co-localization of LTBP-2 with FGF-2 in fibrotic human keloid and hypertrophic scar[J].Journal of Molecular Histology,2016,47(1):35-45. [19]李丽,王林.正常皮肤与病理性瘢痕组织中HIF-1α和促炎细胞因子水平比较及两者相关性研究[J].中国美容医学,2019(28):71-73. [20]董叫云,宋菲,刘英开,等.严重低氧低血清蛋白对人增生性瘢痕成纤维细胞功能的影响[J].中华烧伤杂志,2016(32):594-598. [21]胡强,隋爽,王国栋,等.HIF-1α对病理性瘢痕疙瘩成纤维细胞增殖活力的影响及机制[J].中国生化药物杂志,2016,36(8):43-46,50. [22]Gong T,Zhang C,Kang J,et al.Cryotherapy has antifibrotic and regenerative effects on human vocal fold fibroblasts[J].The Laryngoscope,2018,129(4):E143-E150. [23]Wu X,Li J,Yang X,et al.miR-155 inhibits the formation of hypertrophic scar fibroblasts by targeting HIF-1α via PI3K/AKT pathway[J].Journal of Molecular Histology,2018,49(4):377-387. [24]徐志山,回蔷,李伟,等.miR-194-3p对瘢痕疙瘩成纤维细胞迁移的作用[J].中华整形外科杂志,2018(34):964-970. [25]Dastmalchi DA,Moslemkhani S,Bayat M,et al.The Efficacy of Rituximab in Patients with Mucous Membrane Pemphigoid[J].Journal of Dermatological Treatment,2020(3):1-22. [26]吴晓燕,刘林盛,罗志广,等.病理性瘢痕患者HIF-1α、VEGF、MMP-2的表达及临床意义[J].中国医师杂志,2018(20):1025-1028,1031. [27]范娅琦,郭碧蓉,曾维惠,等.不同能量密度非剥脱点阵激光早期防治兔耳增生性瘢痕的疗效观察[J].中华皮肤科杂志,2018(51):752-755. [28]Ma X,Chen J,Xu B,et al.Keloid-derived keratinocytes acquire a fibroblast-like appearance and an enhanced invasive capacity in a hypoxic microenvironment in vitro[J].International Journal of Molecular Medicine,2015,35(5):1246-1256.