[1]陈友莲,洪澄英,刘晓君,等.不同呼吸支持模式对重症肺炎所致急性呼吸窘迫综合症患者预后的影响[J].医学信息,2021,34(06):126-128.[doi:10.3969/j.issn.1006-1959.2021.06.032]
　CHEN You-lian,HONG Cheng-ying,LIU Xiao-jun,et al.The Influence of Different Respiratory Support Modes on the Prognosis of Patients with Acute Respiratory Distress Syndrome Caused by Severe Pneumonia[J].Medical Information,2021,34(06):126-128.[doi:10.3969/j.issn.1006-1959.2021.06.032]
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不同呼吸支持模式对重症肺炎所致急性呼吸窘迫综合症患者预后的影响()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
34卷
期数:
2021年06期
页码:
126-128
栏目:
临床研究
出版日期:
2021-03-15

文章信息/Info

Title:
The Influence of Different Respiratory Support Modes on the Prognosis of Patients with Acute Respiratory Distress Syndrome Caused by Severe Pneumonia
文章编号:
1006-1959（2021）06-0126-03
作者:
陈友莲; 洪澄英; 刘晓君; 等
（深圳市人民医院重症医学科，广东 深圳 518020）
Author(s):
CHEN You-lian; HONG Cheng-ying; LIU Xiao-jun; et al.
(Department of Critical Care Medicine,Shenzhen People’s Hospital,Shenzhen 518020,Guangdong,China)
关键词:
急性呼吸窘迫综合症; 急性肺损伤; 重症肺炎; HIS系统; 机械通气
Keywords:
Acute respiratory distress syndrome; Acute lung injury; Severe pneumonia; HISsystem; Mechanical ventilation
分类号:
R563
DOI:
10.3969/j.issn.1006-1959.2021.06.032
文献标志码:
A
摘要:
目的 探讨不同呼吸支持模式对重症肺炎所致急性呼吸窘迫综合征（ARDS）患者病死率的影响。方法 收集2014年1月1日~2017年10月31日于我院ICU住院的2852例患者信息，根据ARDS的柏林定义对患者进行筛查，纳入ARDS患者615例，再选择重症肺炎所致的ARDS患者109例进入研究，运用统计学方法对患者一般信息、临床结局、治疗费用等进行分析，比较不同呼吸支持模式对重症肺炎所致ARDS患者生存率的影响。结果 死亡组与生存组性别、年龄、ICU住院日、抗生素费用、住院总费用比较，差异无统计学意义（P＞0.05），不同呼吸支持模式比较，差异有统计学意义（P＜0.05）；多因素分析结果显示，不同呼吸支持模式是患者临床结局（死亡）的独立危险因素（P＜0.05）；病程早期无机械通气组患者生存率最高，高机械通气条件患者生存率优于低机械通气及无创通气条件患者，低机械通气条件患者生存率最差，病程后期无机械通气组患者生存率最高，无创机械通气组患者生存率高于低机械通气组及高机械通气组患者。结论 规范使用不同呼吸支持模式治疗重症肺炎所致ARDS可能改善患者预后，临床应用可行性高。
Abstract:
Objective To explore the effects of different respiratory support modes on the mortality of patients with acute respiratory distress syndrome (ARDS) caused by severe pneumonia.Methods The information of 2852 patients who were hospitalized in the ICU of our hospital from January 1, 2014 to October 31, 2017 were collected.The patients were screened according to the Berlin definition of ARDS, and 615 patients with ARDS were included, and 109 patients with ARDS caused by severe pneumonia were selected for the study.Using statistical methods to analyze the general information of patients, clinical outcomes, treatment costs, etc., and compare the effects of different respiratory support modes on the survival rate of ARDS patients caused by severe pneumonia.Results There was no significant difference between the death group and the survival group in gender, age, ICU hospitalization days, antibiotic expenses, and total hospitalization expenses (P＞0.05).Compared with different respiratory support modes, the difference was statistically significant (P＜0.05);The results of multivariate analysis showed that different modes of respiratory support were independent risk factors for the patient’s clinical outcome (death) (P＜0.05);The survival rate of patients in the non-ventilated group was the highest in the early stage of the disease, and the survival rate of patients with high mechanical ventilation was better than that of patients with low mechanical ventilation and non-invasive ventilation.The survival rate of patients with low mechanical ventilation was the worst, and the survival rate of patients without mechanical ventilation was the highest in the late course of the disease.The survival rate of patients in the non-invasive mechanical ventilation group was higher than that in the low mechanical ventilation group and the high mechanical ventilation group.Conclusion The standardized use of different respiratory support modes in the treatment of ARDS caused by severe pneumonia may improve the prognosis of patients, and the clinical application is highly feasible.

参考文献/References:

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更新日期/Last Update: 1900-01-01