参考文献/References:
[1]O’leary RA,Nichol AD.Pathophysiology of severe traumatic brain injury[J].J Neurosurg Sci,2018,62(5):542-548. [2]唐泽,陶武,王念,等.右美托咪定在颅脑损伤患者术后24h内持续镇静的有效性及安全性[J].重庆医学,2015(11):1533-1534. [3]Abou El Fadl MH,O’Phelan KH.Management of Traumatic Brain Injury:An Update[J].Neurosurg Clin N Am,2018,29(2):213-221. [4]Lee S.Dexmedetomidine:present and future directions[J].Korean J Anesthesiol,2019,72(4):323-330. [5]Alam A,Suen KC,Hana Z,et al.Neuroprotection and neurotoxicity in the developing brain:an update on the effects of dexmedetomidine and xenon[J].Neurotoxicol Teratol,2017(60):102-116. [6]Wang KK,Yang Z,Zhu T,et al.An update on diagnostic and prognostic biomarkers for traumatic brain injury[J].Expert Rev Mol Diagn,2018,18(2):165-180. [7]贺光宏,李杰华,许涛,等.右美托咪定对创伤性颅脑损伤患者术后脑氧代谢及认知功能影响分析[J].中国医学前沿杂志(电子版),2017,9(8):46-50. [8]魏红芳,陈永学,李书河,等.右美托咪定对急性颅脑损伤患者围术期炎性反应的影响[J].中华麻醉学杂志,2012,32(10):1249-1251. [9]许忠玲,范冰冰,郭华,等.右美托咪定对重症颅脑损伤患者围术期血浆S蛋白100B及炎性细胞因子的影响[J].临床麻醉学杂志,2012,28(9):872-874. [10]赵军魁,回丽妹,王云辉,等.右美托咪定对重度颅脑损伤患者血浆S100B蛋白及颅内压的影响[J].中国急救医学,2013,33(8):723-726. [11]焦薇,周脉涛,吴文华,等.右美托咪定与咪唑安定对重型颅脑外伤患者围术期炎症反应及颅内压的影响[J].中国现代医学杂志,2014,24(17):34-38. [12]杨韵锋,卢科.右美托咪啶复合麻醉对硬膜外血肿清除术患者脑保护效应[J].药物流行病学杂志,2015,24(12):709-711. [13]张韫辉,高金贵,张山.右美托咪定对颅脑损伤患者全麻下开颅术时的脑保护作用[J].中华麻醉学杂志,2015,35(1):30-32. [14]凌文娟,沈志强,曹冰,等.右美托咪定对重型颅脑损伤患者术后持续镇静的效果及脑组织的保护作用[J].现代生物医学进展,2016,16(18):3533-3536. [15]徐龙科,刘志武.右美托咪定对全身麻醉下颅脑损伤患者脑保护作用的研究[J].医学综述,2016,22(21):4309-4311. [16]林宗钦,李达宇,王海燕,等.右美托咪啶和丙泊酚对中重度颅脑损伤术后患者脑代谢的影响[J].中国医药科学,2017,7(22):28-31. [17]马丁雷,刘苏,张锦荣,等.右美托咪定在重型颅脑外伤患者手术麻醉中脑保护作用研究[J].陕西医学杂志,2017,46(1):30-32. [18]王高翔,陶蕾,李正民,等.右美托咪定对颅脑损伤手术患者氧化应激反应的影响[J].现代生物医学进展,2017,17(18):3470-3472,3485. [19]何炳华,郭庆聪,黄德辉.右美托咪定对重度颅脑创伤急救患者脑保护作用及其对炎症因子的影响[J].药物生物技术,2018,25(6):496-499. [20]庞小翼,张培根,赵径,等.右美托咪定在颅脑外伤手术患者中的脑保护作用及其对应激反应和炎症因子的影响[J].现代生物医学进展,2018,18(19):3759-3763. [21]杨慧,侯琪,刘德杰.右美托咪定复合丙泊酚对急诊脑外伤手术麻醉患者炎性反应及血流动力学的影响[J].中国药业,2018,27(21):43-45. [22]宋贺,张花平,邱延伟,等.右美托咪定对重症颅脑损伤患者围术期脑组织的保护作用及对血清炎性因子的影响[J].中国医院用药评价与分析,2019,19(5):530-533. [23]孙艳,张娟.右美托咪定注射液用于重度颅脑损伤患者的临床研究[J].中国临床药理学杂志,2019,35(23):2957-2959,2974. [24]吴仲恒,袁海峰,张玉明,等.右美托咪定对颅脑损伤患者Toll样受体4/核因子-κB通路影响[J].临床军医杂志,2019,47(9):961-962,964. [25]Huang Q,Xu H,Xiao QS.Clinical research of different analgesia methods on perianesthetic pain of patients with moderate and severe craniocerebral injury who have emergency operation[J].Eur Rev Med Pharmacol Sci,2017,21(3 Suppl):88-92. [26]Zhao Y,He J,Yu N,et al.Mechanisms of Dexmedetomidine in Neuropathic Pain[J].Front Neurosci,2020(14):330. [27]江基尧.中国颅脑创伤诊治的未来[J].中华神经创伤外科电子杂志,2019,5(5):257-259. [28]Vella MA,Crandall ML,Patel MB.Acute Management of Traumatic Brain Injury[J].Surg Clin North Am,2017,97(5):1015-1030. [29]Graber DJ,Costine BA,Hickey WF.Early inflammatory mediator gene expression in two models of traumatic brain injury:ex vivo cortical slice in mice and in vivo cortical impact in piglets[J].J Neuroinflammation,2015(12):76. [30]Wu J,Vogel T,Gao X,et al.Neuroprotective effect of dexmedetomidine in a murine model of traumatic brain injury[J].Sci Rep,2018,8(1):4935. [31]Liddelow SA,Barres BA.Reactive Astrocytes: Production,Function, and Therapeutic Potential[J].Immunity,2017,46(6):957-967. [32]Gupta K,Rastogi B,Gupta PK,et al.Dexmedetomidine infusion as an anesthetic adjuvant to general anesthesia for appropriate surgical field visibility during modified radical mastectomy with i-gel :a randomized control study[J].Korean J Anesthesiol,2016,69(6):573-578. [33]Kim JK.An introduction to the various role of dexmedetomidine[J].Korean J Anesthesiol,2016,69(6):543-544. [34]Nakhjavan-Shahraki B,Yousefifard M,Oraii A,et al.Meta-analysis of neuron specific enolase in predicting pediatric brain injury outcomes[J].EXCLI J,2017(16):995-1008. [35]Rothaug M,Becker-Pauly C,Rose-John S.The role of interleukin-6 signaling in nervous tissue[J].Biochim Biophys Acta.2016,1863(6 Pt A):1218-1227. [36]Helmy A,De Simoni MG,Guilfoyle MR,et al.Cytokines and innate inflammation in the pathogenesis of human traumatic brain injury[J].Prog Neurobiol,2011,95(3):352-372. [37]Madry C,Attwell D.Receptors,ion channels,and signaling mechanisms underlying microglial dynamics[J].J Biol Chem,2015,290(20):12443-12450. [38]Michetti F,D’Ambrosi N,Toesca A,et al.The S100B story:from biomarker to active factor in neural injury[J].J Neurochem,2019,148(2):168-187. [39]Sheikh MF,Unni N,Agarwal B.Neurological Monitoring in Acute Liver Failure[J].J Clin Exp Hepatol,2018,8(4):441-447. [40]Sinha S,Hudgins E,Schuster J,et al.Unraveling the complexities of invasive multimodality neuromonitoring[J].Neurosurg Focus,2017,43(5):E4. [41]Bunya N,Aisaka W,Miyata K,et al.Prognostic Significance of the Difference Between Mixed and Jugular Venous Oxygen Saturation After Severe Traumatic Brain Injury:A Post Hoc Analysis of the Brain Hypothermia Study[J].World Neurosurg,2020(137):e68-e74.