[1]肖春丽,游 凯,李长青.北京市社区居民大肠癌筛查肠道病变影响因素分析[J].医学信息,2021,34(09):76-80.[doi:10.3969/j.issn.1006-1959.2021.09.020]
　XIAO Chun-li,YOU Kai,LI Chang-qing.Analysis of Influencing Factors of Intestinal Lesions in Colorectal Cancer Screening for Residents in Beijing Community[J].Medical Information,2021,34(09):76-80.[doi:10.3969/j.issn.1006-1959.2021.09.020]
点击复制

北京市社区居民大肠癌筛查肠道病变影响因素分析()
分享到：

医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
34卷
期数:
2021年09期
页码:
76-80
栏目:
论著
出版日期:
2021-05-01

文章信息/Info

Title:
Analysis of Influencing Factors of Intestinal Lesions in Colorectal Cancer Screening for Residents in Beijing Community
文章编号:
1006-1959（2021）09-0076-05
作者:
肖春丽; 游 凯; 李长青
（北京市顺义区疾病预防控制中心，北京 101300）
Author(s):
XIAO Chun-li; YOU Kai; LI Chang-qing
(Beijing Shunyi District Center for Disease Control and Prevention,Beijing 101300,China)
关键词:
大肠癌筛查; 肠道病变; 肠镜检查
Keywords:
Colorectal cancer screening; Intestinal lesions; Colonoscopy
分类号:
R735.34
DOI:
10.3969/j.issn.1006-1959.2021.09.020
文献标志码:
A
摘要:
目的 探讨大肠癌筛查肠道病变的相关因素，为今后制定大肠癌筛查相关防治措施提供科学依据。方法 选取2016年3月~2020年12月北京市顺义区40~74岁居民，完成问卷调查与便潜血检查（FOBT）确定大肠癌高危人群，高危人群行全结肠镜检查，分析肠道病变影响因素。结果 不同性别、年龄、BMI、吸烟情况、糖尿病情况人群病变检出率比较，差异有统计学意义（P＜0.05），不同学历、婚姻状态、肿瘤家族史情况人群病变检出率比较，差异无统计学意义（P＞0.05）；2879例完成肠镜检查的居民中，755例肠镜检查有病变，进展期腺瘤及以上病变者103例，检出率为3.58%；是否有肠息肉史、慢性阑尾炎或阑尾切除史人群检出率比较，差异有统计学意义（P＜0.05）；是否有溃疡性结肠炎、克罗恩病、胃十二指肠溃疡、痔疮、慢性腹泻史、慢性便秘史、黏液或者血便史、慢性胆囊炎或胆囊切除史、不良生活事件史、本人癌症史、一级亲属肠癌史及便潜血检查阳性人群检出率比较，差异无统计学意义（P＞0.05）；多因素Logistic回归分析结果显示，性别、年龄、BMI、慢性阑尾炎或阑尾切除史是肠镜诊断阳性的独立影响因素（P＜0.05）。结论 北京市顺义区大肠癌筛查病变检出率较高，BMI越高、年龄越大的男性更容易检出肠道病变，此类人群应该作为健康教育工作的重点，动员该类人群参与大肠癌筛查工作的基础上，也应着重培养其健康的生活方式，以降低大肠癌的发病风险。
Abstract:
Objective To explore the related factors of colorectal cancer screening for intestinal lesions, and provide scientific basis for the development of related prevention and treatment measures for colorectal cancer screening in the future.Methods From March 2016 to December 2020, residents from 40 to 74 years old in Shunyi District of Beijing were selected to complete a questionnaire and fecal occult blood test (FOBT) to identify high-risk groups of colorectal cancer. High-risk groups underwent colonoscopy to analyze the impact of intestinal lesions factor.Results The difference in the detection rate of lesions among people of different gender, age, BMI, smoking status, and diabetes status was statistically significant (P＜0.05).There was no statistically significant difference in the detection rate of lesions among people with different educational backgrounds, marital status, and family history of tumors (P＞0.05);Among the 2879 residents who completed colonoscopy, 755 had lesions under colonoscopy, 103 had advanced adenoma and above, and the detection rate was 3.58%;Whether there was a history of intestinal polyps, chronic appendicitis or history of appendicectomy, the difference was statistically significant (P＜0.05);Whether there was ulcerative colitis, Crohn’s disease, gastroduodenal ulcer, hemorrhoids, history of chronic diarrhea, history of chronic constipation, history of mucus or blood in the stool, history of chronic cholecystitis or cholecystectomy, history of adverse life events, history of cancer, comparison of the detection rate of people with a history of bowel cancer in first-degree relatives and positive fecal occult blood tests,the difference was not statistically significant (P＞0.05);The results of multivariate Logistic regression analysis showed that gender, age, BMI, chronic appendicitis or history of appendectomy were independent influencing factors for positive colonoscopy diagnosis (P＜0.05).Conclusion The detection rate of colorectal cancer screening lesions in Shunyi District of Beijing is higher. Men with higher BMI and older are more likely to detect intestinal lesions. This group of people should be the focus of health education and mobilize this group of people to participate in the colorectal cancer. On the basis of cancer screening, we should also focus on cultivating a healthy lifestyle to reduce the risk of colorectal cancer.

参考文献/References:

[1]于新明,林国乐,邱辉忠.HGF/c-Met信号通路及其调控基因MACC-1与结肠直肠癌转移的关系[J].癌症进展,2010,8(5):441-444. [2]Lin JB,Zhang L,Wu DW,et al.Validation of the chinese version of the EORTC QLQ-CR29 in patients with colorectal cancer[J].World J Gastroenterol,2017,23(10):1891-1898. [3]Stiggelbout AM,Kunneman M,Baas-Thijssen MC,et al.The EORTC QLQ-CR29 quality of life questionnaire for colorectal cancer:validation of the Dutch version[J].Qual Life Res,2016,25(7):1853-1858. [4]李攻克.老年结肠癌致急性肠梗阻106例治疗体会[J].医学理论与实践,2015,(14):1901-1902. [5]陈万青,李霓,兰平,等.中国结直肠癌筛查与早诊早治指南(2020,北京)[J].中国肿瘤,2021,30(1):1-28. [6]徐永成.大肠癌的流行病学和病因研究[J].医学综述,2005,11(7):615-616. [7]袁延楠,杨雷,张希,等.2014~2017年北京市城市结直肠癌早诊早治项目筛查结果分析[J].中国公共卫生,2020,36(1):33-35. [8]国家消化系统疾病临床医学研究中心(上海),国家消化道早癌防治中心联盟,中华医学会消化内镜学分会,等.中国早期结直肠癌筛查流程专家共识意见(2019,上海)[J].中华消化内镜杂志,2019,36(10):709-719. [9]李静,庄丽燕,黄铖,等.2015~2017年上海市松江区中山街道社区大肠癌筛查情况和肠镜检查顺应性及其异常病变的影响因素研究[J].中国全科医学,2018,21(24):2904-2909. [10]Ma GK,Ladabaum U.Personalizing colorectal cancer screening:a systematic review of models to predict risk of colorectal neoplasia[J].Clin Gastroenterol Hepatol,2014,12(10):1624-1634. [11]袁延楠,杨雷,张希,等.2014~2017年北京市城市结直肠癌早诊早治项目筛查结果分析[J].中国公共卫生,2020,36(1):33-35. [12]肖春丽,游凯,程文龙,等.北京市顺义区大肠癌筛查745例肠镜检查结果分析[J].肿瘤预防与治疗,2016,29(4):239-241. [13]李江波,孙聪,孙常波,等.内镜下黏膜切除术治疗大肠广基息肉患者的临床疗效评价[J].中国药物与临床,2019(7):1095-1096. [14]陈瑛罡.BMI指数与大肠癌发生机制的相关性研究[J].中华结直肠疾病电子杂志,2015,4(3):27-30. [15]韦佳佳,唐振柱,李忠友,等.广西五县结直肠癌影响因素的病例对照研究[J].应用预防医学,2019,25(1):9-13. [16]郁雨婷,赵根明,郁建国,等.上海市松江区结直肠癌发病危险因素研究[J].中国全科医学,2018,21(30):3709-3713.

更新日期/Last Update: 1900-01-01