[1]宋 硕,张 颖,陈国通,等.细胞周期蛋白D与女性恶性肿瘤的关系[J].医学信息,2021,34(10):36-38.[doi:10.3969/j.issn.1006-1959.2021.10.010]
　SONG Shuo,ZHANG Ying,CHEN Guo-tong,et al.The Relationship Between Cyclin D and Female Malignant Tumors[J].Medical Information,2021,34(10):36-38.[doi:10.3969/j.issn.1006-1959.2021.10.010]
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细胞周期蛋白D与女性恶性肿瘤的关系()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
34卷
期数:
2021年10期
页码:
36-38
栏目:
综述
出版日期:
2021-05-15

文章信息/Info

Title:
The Relationship Between Cyclin D and Female Malignant Tumors
文章编号:
1006-1959（2021）10-0036-03
作者:
宋 硕; 张 颖; 陈国通; 等
（1.广东医科大学，广东 湛江 524000；2.广东医科大学附属医院，广东 湛江 524000）
Author(s):
SONG Shuo; ZHANG Ying; CHEN Guo-tong; et al.
(1.Guangdong Medical University,Zhanjiang 524000,Guangdong,China;2.The Affiliated Hospital of Guangdong Medical University,Zhanjiang 524000,Guangdong,China)
关键词:
细胞周期蛋白; 乳腺癌; 微小RNA
Keywords:
Cyclin; Breast cancer; MicroRNA
分类号:
R737
DOI:
10.3969/j.issn.1006-1959.2021.10.010
文献标志码:
A
摘要:
细胞周期蛋白是广泛存在于真核细胞，具有稳定保守结构的一类蛋白分子，通过与周期蛋白依赖性激酶（CDK）结合形成驱动复合物，参与整个细胞周期过程，其中细胞周期蛋白D（CCND）是其中研究较多的一种蛋白，被认为是肿瘤表型和疾病进展的生物标记，已证实与乳腺癌、卵巢癌、宫颈癌、子宫内膜癌有密切关系。本文就细胞周期蛋白D的分类、功能及其与女性恶性肿瘤的关系作一综述，以期为女性恶性肿瘤的诊治提供参考依据。
Abstract:
Cyclin is a type of protein molecule with a stable and conserved structure widely found in eukaryotic cells. It forms a driving complex by combining with cyclin-dependent kinase (CDK) and participates in the entire cell cycle process.Among them, Cyclin D (CCND) is one of the most studied proteins. It is considered to be a biomarker of tumor phenotype and disease progression. It has been proved to be closely related to breast cancer, ovarian cancer, cervical cancer, and endometrial cancer.This article reviews the classification and function of cyclin D and its relationship with female malignant tumors, hoping to provide a reference for the diagnosis and treatment of female malignant tumors.

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更新日期/Last Update: 1900-01-01