[1]刘 鑫,付俊淇,孟凡荣.DWI和MRS对脑转移瘤瘤周水肿的诊断价值[J].医学信息,2021,34(16):190-192.[doi:10.3969/j.issn.1006-1959.2021.16.055]
　LIU Xin,FU Jun-qi,MENG Fan-rong.The Diagnostic Value of DWI and MRS in Peritumoral Edema of Brain Metastases[J].Medical Information,2021,34(16):190-192.[doi:10.3969/j.issn.1006-1959.2021.16.055]
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DWI和MRS对脑转移瘤瘤周水肿的诊断价值()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
34卷
期数:
2021年16期
页码:
190-192
栏目:
诊疗技术
出版日期:
2021-08-15

文章信息/Info

Title:
The Diagnostic Value of DWI and MRS in Peritumoral Edema of Brain Metastases
文章编号:
1006-1959（2021）16-0190-03
作者:
刘 鑫; 付俊淇; 孟凡荣
（1.佳木斯大学附属第一医院医学影像中心，黑龙江 佳木斯 154002； 2.佳木斯市中心医院骨科，黑龙江 佳木斯 154002； 3.佳木斯大学第一附属医院影像科，黑龙江 佳木斯 154002）
Author(s):
LIU Xin; FU Jun-qi; MENG Fan-rong
(1.Medical Imaging Center,the First Affiliated Hospital of Jiamusi University,Jiamusi 154002,Heilongjiang,China; 2.Department of Orthopedics,the Central Hospital of Jiamusi City,Jiamusi 154002,Heilongjiang,China; 3.Department of Imaging,the First Affiliat
关键词:
磁共扩散加权成像; 氢质子磁共振波谱; 脑肿瘤; 瘤周水肿
Keywords:
Diffusion Weighted Imaging; Proton magnetic resonance spectroscopy; Brain tumor; Peritumoral edema
分类号:
R445.2；R739.41
DOI:
10.3969/j.issn.1006-1959.2021.16.055
文献标志码:
A
摘要:
目的 研究磁共扩散加权成像（DWI）和氢质子磁共振波谱（1H-MRS）对脑肿瘤瘤周水肿的鉴别诊断价值。方法 选取2018年6月~2021年1月佳木斯大学附属第一医院进行检查并经手术病理证实的脑转移瘤患者80例为研究对象，其中单发脑转移瘤42例，多发脑转移瘤38例，均进行常规MRI检查及增强扫描、单体素1H-MRS扫描，测定两组肿瘤周水肿和对侧正常脑组织的平均表观弥散值（ADC）、氮－乙酰天门冬氨酸（NAA）、胆碱（Cho）、肌酸（Cr）和Cho/Cr、NAA/Cr比值以及ADC值与Cho/Cr的相关性。结果 单发脑转移瘤瘤周水肿ADC大于对侧正常脑组织，Cho/Cr、NAA/Cr比值均低于对侧正常脑组织，差异有统计学意义（P＜0.05）；多发脑转移瘤瘤周水肿ADC、Cho/Cr、大于对侧正常脑组织，NAA/Cr低于对侧正常脑组织，差异有统计学意义（P＜0.05）；多发脑转移瘤瘤周水肿ADC值与Cho/Cr比值之间呈负相关（r=-0.678，P=0.025）；单发脑转移瘤瘤周水肿ADC值与Cho/Cr比值无相关性（r=-0.126，P=0.956）。结论 DWI联合MRS测定ADC对脑转移瘤瘤周水肿的鉴别诊断价值具有重要价值，尤其多发脑转移瘤周水肿ADC值与Cho/Cr比值密切相关，可为鉴别单发和多发脑转移瘤提供影像学依据。
Abstract:
Objective To study the differential diagnosis value of magnetic co-diffusion weighted imaging (DWI) and hydrogen proton magnetic resonance spectroscopy(1H-MRS)for brain tumor peritumoral edema.Methods A total of 80 patients with brain metastases who were examined by the First Affiliated Hospital of Jiamusi University from June 2018 to January 2021 and confirmed by surgery and pathology were selected as the research objects.Among them, 42 cases of single brain metastases, 38 cases of multiple brain metastases, all underwent routine MRI examination, enhanced scan, and single voxel 1H-MRS scan.Measure the average apparent dispersion value (ADC) of the peritumor edema and the contralateral normal brain tissue in the two groups,Nitrogen-acetylaspartic acid (NAA), choline (Cho), creatine (Cr) and Cho/Cr, NAA/Cr ratio and the correlation between ADC value and Cho/Cr.Results The ADC of peritumoral edema in the single brain metastasis group was greater than that of the contralateral normal brain tissue, and the ratios of Cho/Cr and NAA/Cr were lower than those of the contralateral normal brain tissue,the difference was statistically significant (P<0.05);The peritumoral edema of brain metastases in the multiple group had higher ADC and Cho/Cr than the contralateral normal brain tissue, and NAA/Cr was lower than the contralateral normal brain tissue,the difference was statistically significant(P<0.05);There was a negative correlation between the ADC value of peritumoral edema of brain metastases in the multiple group and the Cho/Cr ratio (r=-0.678, P=0.025);There was no correlation between ADC value of peritumoral edema of brain metastases in single group and Cho/Cr ratio (r=-0.126, P=0.956).Conclusion DWI combined with MRS measurement of ADC has important value in the differential diagnosis of peritumoral edema in brain metastases.In particular, the ADC value of peritumoral edema of multiple brain metastases is closely related to the Cho/Cr ratio, which can provide imaging evidence for distinguishing single and multiple brain metastases.

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更新日期/Last Update: 1900-01-01