[1]罗章才,钟绍东,陈康福.瑞芬太尼联合丙泊酚靶控输注对超低位直肠癌手术患者术后苏醒时间及并发症的影响[J].医学信息,2021,34(24):77.[doi:10.3969/j.issn.1006-1959.2021.24.016]
　LUO Zhang-cai,ZHONG Shao-dong,CHEN Kang-fu.Effect of Remifentanil Combined with Propofol Target-controlled Infusion on Postoperative Recovery Time and Complications in Patients with Ultra-low Rectal Cancer[J].Medical Information,2021,34(24):77.[doi:10.3969/j.issn.1006-1959.2021.24.016]
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瑞芬太尼联合丙泊酚靶控输注对超低位直肠癌手术患者术后苏醒时间及并发症的影响()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
34卷
期数:
2021年24期
页码:
77
栏目:
论著
出版日期:
2021-12-15

文章信息/Info

Title:
Effect of Remifentanil Combined with Propofol Target-controlled Infusion on Postoperative Recovery Time and Complications in Patients with Ultra-low Rectal Cancer
文章编号:
1006-1959（2021）24-0077-04
作者:
罗章才; 钟绍东; 陈康福
（于都县人民医院麻醉科，江西 于都 342300）
Author(s):
LUO Zhang-cai; ZHONG Shao-dong; CHEN Kang-fu
(Department of Anesthesiology,Yudu County People’s Hospital,Yudu 342300,Jiangxi,China)
关键词:
直肠癌; 超低位手术; 瑞芬太尼; 丙泊酚; 麻醉苏醒时间; 认知功能
Keywords:
Rectal cancer; Ultra-low surgery; Remifentanil; Propofol; Anesthesia recovery time; Cognitive function
分类号:
R735.3+7
DOI:
10.3969/j.issn.1006-1959.2021.24.016
文献标志码:
A
摘要:
目的 探究瑞芬太尼联合丙泊酚靶控输注对超低位直肠癌手术患者术后苏醒时间及并发症的影响。方法 选取2019年7月-2021年7月于都县人民医院收治的62例直肠癌患者，采用随机数字表法分为对照组和观察组，每组31例。所有患者均接受超低位直肠癌手术治疗，对照组采用瑞芬太尼联合丙泊酚静脉持续输注麻醉，观察组采用瑞芬太尼联合丙泊酚靶控输注麻醉。比较两组麻醉优良率、术后恢复时间（呼吸恢复时间、术后苏醒时间、拔管时间）、血流动力学水平[平均动脉压（MAP）、心率（HR）]、认知功能[简易精神状态检查量表（MMSE）评分]及麻醉并发症情况。结果 两组麻醉优良率对比，差异无统计学意义（P＞0.05）。观察组呼吸恢复时间、术后苏醒时间、拔管时间均短于对照组，差异有统计学意义（P＜0.05）。两组围术期MAP、HR水平对比，差异无统计学意义（P＞0.05）。但观察组MAP、HR波动值小于对照组，差异有统计学意义（P＜0.05）。术后，两组MMSE评分均有下降，但观察组术后MMSE评分高于对照组，差异有统计学意义（P＜0.05）。观察组麻醉并发症发生率低于对照组（9.68% vs 32.26%），差异有统计学意义（P＜0.05）。结论 瑞芬太尼联合丙泊酚靶控输注用于超低位直肠癌手术，效果确切，可在保证麻醉效果的同时缩短术后苏醒时间，维持血流动力学稳定，减少认知功能损害，降低并发症风险。
Abstract:
Objective To investigate the effect of remifentanil combined with propofol target controlled infusion on postoperative recovery time and complications in patients with ultra-low rectal cancer.Methods A total of 62 patients with rectal cancer admitted to Yudu County People’s Hospital from July 2019 to July 2021 were selected and randomly divided into control group and observation group, with 31 cases in each group. All patients underwent ultra-low rectal cancer surgery. The control group received remifentanil combined with propofol intravenous continuous infusion anesthesia, and the observation group received remifentanil combined with propofol target controlled infusion anesthesia. The excellent and good rate of anesthesia, postoperative recovery time (respiratory recovery time, postoperative recovery time, extubation time), hemodynamic levels [mean arterial pressure (MAP), heart rate (HR)], cognitive function [mini-mental state examination (MMSE) score] and anesthesia complications were compared between the two groups.Results There was no significant difference in the excellent and good rate of anesthesia between the two groups (P>0.05). The respiratory recovery time, postoperative recovery time and extubation time in the observation group were shorter than those in the control group, and the difference was statistically significant (P<0.05). There was no significant difference in perioperative MAP and HR between the two groups (P>0.05), but the fluctuation values of MAP and HR in the observation group were lower than those in the control group, and the difference was statistically significant (P<0.05). After operation, the MMSE scores of the two groups decreased, but the MMSE score of the observation group was higher than that of the control group, and the difference was statistically significant (P<0.05). The incidence of anesthesia complications in the observation group was lower than that in the control group (9.68% vs 32.26%), and the difference was statistically significant (P<0.05).Conclusion Remifentanil combined with propofol target-controlled infusion for ultra-low rectal cancer surgery is effective, which can shorten the postoperative recovery time, maintain hemodynamic stability, reduce cognitive impairment and reduce the risk of complications while ensuring the anesthetic effect.

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更新日期/Last Update: 1900-01-01