[1]唐伟京.龙胆泻肝汤加味治疗带状疱疹的疗效及对后遗神经痛的影响[J].医学信息,2022,35(01):168-170.[doi:10.3969/j.issn.1006-1959.2022.01.042]
 TANG Wei-jing.Effect of Longdan Xiegan Decoction in the Treatment of Herpes Zoster and its Effect on Postherpetic Neuralgia[J].Medical Information,2022,35(01):168-170.[doi:10.3969/j.issn.1006-1959.2022.01.042]
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龙胆泻肝汤加味治疗带状疱疹的疗效及对后遗神经痛的影响()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
35卷
期数:
2022年01期
页码:
168-170
栏目:
中医中药
出版日期:
2022-01-01

文章信息/Info

Title:
Effect of Longdan Xiegan Decoction in the Treatment of Herpes Zoster and its Effect on Postherpetic Neuralgia
文章编号:
1006-1959(2022)01-0168-03
作者:
唐伟京
(首都医科大学石景山教学医院/北京市石景山医院中医科,北京 100043)
Author(s):
TANG Wei-jing
(Department of Traditional Chinese Medicine,Shijingshan Teaching Hospital of Capital Medical University/Beijing Shijingshan Hospital,Beijing 100043,China)
关键词:
龙胆泻肝汤加味泛昔洛韦带状疱疹后遗神经痛
Keywords:
Longdan Xiegan decoctionFamciclovirHerpes zosterLegacy neuralgia
分类号:
R752.1+2
DOI:
10.3969/j.issn.1006-1959.2022.01.042
文献标志码:
A
摘要:
目的 研究龙胆泻肝汤加味治疗带状疱疹的临床疗效及对后遗神经痛的影响。方法 选取2016年4月-2019年4月在北京市石景山医院接受治疗的90例带状疱疹患者为研究对象,随机分为研究组和对照组,每组45例。对照组采用常规西药治疗,研究组采用龙胆泻肝汤加味治疗。比较两组患者疼痛程度(VAS评分)、治疗效果、后遗神经痛发生率及临床指标改善情况。结果 研究组VAS评分为(1.85±1.37)分,低于对照组的(3.06±1.24)分,差异有统计学意义(P<0.05)。研究组治疗总有效率为93.33%,高于对照组的75.56%,差异有统计学意义(P<0.05)。研究组后遗痛发生率为8.89%,低于对照组的24.44%,差异有统计学意义(P<0.05)。研究组止疱时间、结痂时间、疼痛消失时间分别为(1.18±1.05)d、(3.05±0.68)d、(3.04±0.67)d,均短于对照组的(2.57±1.25)d、(5.21±0.57)d、(4.78±0.87)d,差异有统计学意义(P<0.05)。结论 采用龙胆泻肝汤加味治疗带状疱疹疗效显著,能够有效减轻疼痛程度,降低后遗神经痛发生率,提高治愈率,促进患者康复。
Abstract:
Objective To study the clinical efficacy of Longdan Xiegan decoction in the treatment of herpes zoster and its influence on postherpetic neuralgia.Methods A total of 90 patients with herpes zoster treated in Beijing Shijingshan Hospital from April 2016 to April 2019 were randomly divided into study group and control group, with 45 cases in each group. The control group was treated with conventional western medicine, and the study group was treated with Longdan Xiegan decoction. The degree of pain (VAS score), therapeutic effect, incidence of sequelae and improvement of clinical indicators were compared between the two groups.Results The VAS score of the study group was (1.85±1.37) scores, which was lower than that of the control group (3.06±1.24) scores, and the difference was statistically significant (P<0.05). The total effective rate of the study group was 93.33%, which was higher than 75.56% of the control group , and the difference was statistically significant (P<0.05). The incidence of postoperative pain in the study group was 8.89%, which was lower than 24.44% in the control group, and the difference was statistically significant (P<0.05). The blister stopping time, scab forming time and pain disappearance time in the study group were (1.18±1.05)d,(3.05±0.68)d and (3.04±0.67)d respectively, which were shorter than (2.57±1.25)d, (5.21±0.57)d and (4.78±0.87)d in the control group, the difference was statistically significant (P<0.05).Conclusion Modified Longdan Xiegan decoction is effective in the treatment of herpes zoster, which can effectively reduce the degree of pain, reduce the incidence of postherpetic neuralgia, improve the cure rate and promote the rehabilitation of patients.

参考文献/References:

[1]张学军.皮肤性病学[M].北京:人民卫生出版社,2013:65-67.[2]丁雄,蒋蔚,蒋静.基于健康大数据带状疱疹与抑郁症的关系——现实世界的研究实例[J].中华疾病控制杂志,2021,25(6):730-733.[3]严妍.龙胆泻肝汤治疗带状疱疹随机对照实验的系统评价附:36例肝胆湿热型蛇串疮的临床观察[D].昆明:云南中医学院,2016.[4]刘靖芷,史可梅,马文庭,等.半月神经节阿霉素化学损毁术与射频热凝术对头面部带状疱疹后遗神经痛疗效的比较[J].中华麻醉学杂志,2018,38(8):933-936.[5]国家中医药管理局医政司.中医病证诊断疗效标准[M].北京:中国中医药出版社,2018:31-32.[6]梁家芬,刘玉香,李红毅,等.范瑞强从肝论治皮肤病经验撷粹[J].江苏中医药,2020,52(6):25-27.[7]王中江,张理涛.从心论治带状疱疹后遗神经痛[J].内蒙古中医药,2021,40(2):92-93.[8]陈明玲,过伟峰.从风痰瘀阻论治带状疱疹后遗神经痛[J].湖北民族学院学报(医学版),2019,36(1):62-63.[9]李少波,李程,陈思,等.伐昔洛韦联合膦甲酸钠治疗老年人头面部带状疱疹的疗效[J].武汉大学学报(医学版),2019,40(5):829-832.[10]谢艳秋,徐永梓.栗锦迁教授中医辨治带状疱疹神经痛验案4则[J].中国中西医结合皮肤性病学杂志,2020,19(5):482-485.[11]伍小敏,于泳健,蔡放,等.带状疱疹后遗神经痛的发病相关因素分析[J].中华全科医学,2016,14(3):352-354.[12]陈慧娟,洪文,成林平,等.带痛方治疗带状疱疹后遗神经痛临床观察[J].新中医,2018,50(8):164-166.[13]吴伟莲,黄昌锦,曹桂娴.龙胆泻肝汤治疗带状疱疹的效果及对p38MAPK基因表达的影响[J].中国医药导报,2018,15(12):144-147.[14]秦涛,赵婵.龙胆泻肝汤联合常规抗病毒治疗伴中重度抑郁带状疱疹[J].吉林中医药,2018,38(7):63-66.[15]陆谛.难治性带状疱疹后神经痛危险因素分析[D].太原:山西医科大学,2020.[16]于志国,姚雪靖,粱瑞阁,等.化瘀通络理论指导下中医综合疗法治疗带状疱疹后遗神经痛的临床研究[J].河北中医,2018,40(7):1021-1024.[17]赵炳南,张志礼,主编.简明中医皮肤病学[M].北京:中国中医药出版社,2014:131-133.[18]王建青.龙胆泻肝汤的渊源及临床应用概况[J].中医药通报,2020,19(2):41-43.[19]张颖纯,杨敏,邓田睿.疏肝活血汤合泛昔洛韦片治疗带状疱疹的临床观察[J].中国中西医结合皮肤性病学杂志,2018,17(2):154-155.[20]李晓刚,陈耀辉.芍药甘草汤功用新识[J].辽宁中医杂志,2018,23(10):2083-2085.

更新日期/Last Update: 1900-01-01