[1]邵景萍.HPV联合TCT检测在宫颈疾病筛查中的应用[J].医学信息,2022,35(10):168-170.[doi:10.3969/j.issn.1006-1959.2022.10.043]
　SHAO Jing-ping.Application of HPV Combined with TCT in Cervical Disease Screening[J].Medical Information,2022,35(10):168-170.[doi:10.3969/j.issn.1006-1959.2022.10.043]
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HPV联合TCT检测在宫颈疾病筛查中的应用()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
35卷
期数:
2022年10期
页码:
168-170
栏目:
诊疗技术
出版日期:
2022-05-15

文章信息/Info

Title:
Application of HPV Combined with TCT in Cervical Disease Screening
文章编号:
1006-1959（2022）10-0168-03
作者:
邵景萍
（天津市蓟州区人民医院妇科，天津 301900）
Author(s):
SHAO Jing-ping
(Department of Gynecology,Tianjin Jizhou District People’s Hospital,Tianjin 301900,China)
关键词:
HPV; TCT; 宫颈疾病; 敏感度
Keywords:
HPV; TCT; Cervical disease; Sensitivity
分类号:
R711.74
DOI:
10.3969/j.issn.1006-1959.2022.10.043
文献标志码:
A
摘要:
目的 研究HPV联合TCT检测在宫颈疾病筛查中的应用价值。方法 选取2020年3月-2021年3月在我院进行宫颈疾病筛查的3160例患者为研究对象，均行人乳头瘤病毒（HPV）、薄层液基细胞学（TCT）以及HPV联合TCT检查，比较不同年龄段HPV分型阳性检出率；以病理活检为诊断标准，比较HPV、TCT及HPV联合TCT检查的诊断敏感度、特异度、准确性。结果 HPV分型阳性检出率为23.41%，35~44岁、45~54岁年龄段阳性率高于18~24岁、25~34岁及≥55岁年龄段（P＜0.05），45~54岁年龄段HPV 16、18型阳性率均高于其他年龄段（P＜0.05）；TCT检出高危HPV阳性率为41.49%，病理学检测阳性符合率为89.25%；HPV联合TCT检查的敏感度高于HPV、TCT检查，且HPV的敏感度高于TCT（P＜0.05）；HPV联合TCT检查的特异度高于TCT、HPV，但TCT与HPV的特异度比较，差异无统计学意义（P＞0.05）；HPV联合TCT检查的准确度高于TCT、HPV，但TCT的准确度高于HPV（P＜0.05）。结论 在宫颈疾病筛查中应用HPV联合TCT检查准确度、敏感度以及特异度均较高，可及早诊断宫颈疾病，为临床及时有效治疗提供参考依据。
Abstract:
Objective To study the application value of HPV combined with TCT in cervical disease screening.Methods A total of 3160 patients who underwent cervical disease screening in our hospital from March 2020 to March 2021 were selected as the subjects. All of them were examined by human papillomavirus (HPV), thin-layer liquid-based cytology (TCT) and HPV combined with TCT. The positive detection rate of HPV typing in different age groups was compared. The diagnostic sensitivity, specificity and accuracy of HPV, TCT and HPV combined with TCT were compared.Results The positive rate of HPV typing was 23.41%, the positive rates of 35-44 years old and 45-54 years old were higher than those of 18-24 years old, 25-34 years old and ≥55 years old (P<0.05), and the positive rates of HPV 16 and 18 in 45-54 age group were higher than those in other age groups (P<0.05). The positive rate of high-risk HPV detected by TCT was 41.49%, and the positive coincidence rate of pathological detection was 89.25%. The sensitivity of HPV combined with TCT was higher than that of HPV and TCT, and the sensitivity of HPV was higher than that of TCT (P<0.05). The specificity of HPV combined with TCT was higher than that of TCT and HPV, but the difference between TCT and HPV was not statistically significant (P>0.05). The accuracy of HPV combined with TCT was higher than that of TCT and HPV, but the accuracy of TCT was higher than that of HPV (P<0.05).Conclusion The accuracy, sensitivity and specificity of HPV combined with TCT in cervical disease screening are high, which can diagnose cervical disease early and provide reference for timely and effective treatment.

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更新日期/Last Update: 1900-01-01