[1]程 瑶,张 震,赵 锐,等.咽喉反流疾病与下咽癌的相关性的研究进展[J].医学信息,2022,35(12):65-67,72.[doi:10.3969/j.issn.1006-1959.2022.12.015]
 CHENG Yao,ZHANG Zhen,ZHAO Rui,et al.Research Progress on the Correlation Between Laryngopharyngeal Reflux Disease and Hypopharyngeal Carcinoma[J].Medical Information,2022,35(12):65-67,72.[doi:10.3969/j.issn.1006-1959.2022.12.015]
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咽喉反流疾病与下咽癌的相关性的研究进展()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
35卷
期数:
2022年12期
页码:
65-67,72
栏目:
综述
出版日期:
2022-06-15

文章信息/Info

Title:
Research Progress on the Correlation Between Laryngopharyngeal Reflux Disease and Hypopharyngeal Carcinoma
文章编号:
1006-1959(2022)12-0065-04
作者:
程 瑶张 震赵 锐
(川北医学院附属医院耳鼻喉头颈外科,四川 南充 637000)
Author(s):
CHENG YaoZHANG ZhenZHAO Ruiet al.
(Department of Otolaryngology,Head and Neck Surgery,Affiliated Hospital of North Sichuan Medical College,Nanchong 637000,Sichuan,China)
关键词:
下咽癌咽喉反流胃蛋白酶
Keywords:
hypopharyngeal cancerLaryngopharyngeal refluxPepsin
分类号:
R766;R739.63
DOI:
10.3969/j.issn.1006-1959.2022.12.015
文献标志码:
A
摘要:
下咽癌是耳鼻咽喉头颈外科最常见的恶性肿瘤之一,其发病率逐年增加,且该疾病预后较差。咽喉反流是导致下咽癌发生发展的危险因素之一,其致病机制为咽喉反流中的内容物,如胃蛋白酶、胆汁酸盐、胃酸等物质均可损伤咽喉部黏膜细胞,从而诱导下咽癌的发生。因此,有效地预防及治疗咽喉反流疾病,对预防下咽癌发生具有重要意义。本文从咽喉反流的发生机制、咽喉反流内容物致病机制及咽喉反流的诊断作一综述。
Abstract:
Hypopharyngeal carcinoma is one of the most common malignant tumors in otolaryngology head and neck surgery. The incidence of hypopharyngeal carcinoma is increasing year by year, and the prognosis is poor. Laryngeal reflux is one of the risk factors leading to the occurrence and development of hypopharyngeal carcinoma. The pathogenic mechanism of laryngopharyngeal reflux is that the contents of laryngopharyngeal reflux, such as pepsin, bile acid salt, gastric acid and other substances can damage the throat mucosal cells, thus inducing the occurrence of hypopharyngeal carcinoma. Therefore, effective prevention and treatment of laryngopharyngeal reflux disease is of great significance to the prevention of hypopharyngeal carcinoma. This paper reviews the pathogenesis of laryngopharyngeal reflux, the pathogenesis of laryngopharyngeal reflux content and the diagnosis of laryngopharyngeal reflux.

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更新日期/Last Update: 1900-01-01