[1]陈云华.肝脏疾病与内分泌代谢疾病的相关性[J].医学信息,2022,35(18):96-98.[doi:10.3969/j.issn.1006-1959.2022.18.025]
　CHEN Yun-hua.Correlation Between Liver Diseases and Endocrine Metabolic Diseases[J].Journal of Medical Information,2022,35(18):96-98.[doi:10.3969/j.issn.1006-1959.2022.18.025]
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肝脏疾病与内分泌代谢疾病的相关性()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
35卷
期数:
2022年18期
页码:
96-98
栏目:
临床研究
出版日期:
2022-09-15

文章信息/Info

Title:
Correlation Between Liver Diseases and Endocrine Metabolic Diseases
文章编号:
1006-1959（2022）18-0096-03
作者:
陈云华
（遂宁市第三人民医院内三科，四川 遂宁 629000）
Author(s):
CHEN Yun-hua
(The Third Department of Internal Medicine,Suining Third People’s Hospital,Suining 629000,Sichuan,China)
关键词:
肝脏疾病; 内分泌代谢; 肝损害; 肝功能
Keywords:
Liver disease; Endocrine metabolism; Liver damage; Liver function
分类号:
R58；R57
DOI:
10.3969/j.issn.1006-1959.2022.18.025
文献标志码:
A
摘要:
目的 研究肝脏疾病与内分泌代谢疾病的相关性。方法 选取2020年7月-2021年7月在我院诊治的122例内分泌代谢疾病患者为研究对象，其中2型糖尿病38例，甲状腺功能亢进26例，肾功能衰竭30例，性功能障碍28例，另选取同期体检健康者120名为对照组，比较各疾病患者及对照组肝功能指标水平、肝功能异常发生率、合并肝脏疾病发生率、预后及转归。结果 2型糖尿病、甲状腺功能亢进、肾功能衰竭、性功能障碍患者血清丙氨酸氨基转移酶（ALT）、天门冬氨酸氨基转移酶（AST）、谷氨酰基转移酶（GGT）水平均高于对照组（P＜0.05）；甲状腺功能亢进、肾功能衰竭患者肝功能异常发生率高于2型糖尿病、性功能障碍患者，且肾功能衰竭患者肝功能异常发生率高于甲状腺功能亢进患者（P＜0.05）；2型糖尿病、性功能障碍患者肝功能异常发生率比较，差异无统计学意义（P＞0.05）；肾功能衰竭患者合并肝脏疾病发生率高于2型糖尿病、甲状腺功能亢进、性功能障碍患者，甲状腺功能亢进患者合并肝脏疾病发生率高于2型糖尿病、性功能障碍患者（P＜0.05）；Pearson相关性分析显示，内分泌代谢疾病患者合并肝脏疾病发生率与肝功能指标水平呈正相关（P＜0.05），与肝功能异常发生率无相关性（P＞0.05）。结论 肝脏疾病与内分泌代谢具有一定的关系，可与肝脏疾病共同存在，肝脏疾病会增加肝功能损害，临床在治疗内分泌代谢疾病的同时，应辅以保肝治疗，使患者随着病情的好转肝功能逐渐恢复正常，进一步改善预后。
Abstract:
Objective To study the correlation between liver diseases and endocrine and metabolic diseases.Methods A total of 122 patients with endocrine and metabolic diseases diagnosed and treated in our hospital from July 2020 to July 2021 were selected as the study subjects, including 38 patients with type 2 diabetes, 26 patients with hyperthyroidism, 30 patients with renal failure, and 28 patients with sexual dysfunction. Another 120 healthy subjects who underwent physical examination during the same period were selected as the control group. The levels of liver function indexes, the incidence of abnormal liver function, the incidence of combined liver disease, prognosis and outcome were compared between the patients with various diseases and the control group.Results The levels of serum alanine aminotransferase (ALT), aspartate aminotransferase (AST) and glutamyl transferase (GGT) in patients with type 2 diabetes, hyperthyroidism, renal failure and sexual dysfunction were higher than those in control group (P＜0.05). The incidence of abnormal liver function in patients with hyperthyroidism and renal failure was higher than that in patients with type 2 diabetes and sexual dysfunction, and the incidence of abnormal liver function in patients with renal failure was higher than that in patients with hyperthyroidism (P＜0.05). There was no significant difference in the incidence of abnormal liver function between patients with type 2 diabetes and sexual dysfunction (P＞0.05). The incidence of liver disease in patients with renal failure was higher than that in patients with type 2 diabetes, hyperthyroidism and sexual dysfunction, and the incidence of liver disease in patients with hyperthyroidism was higher than that in patients with type 2 diabetes and sexual dysfunction (P＜0.05). Pearson correlation analysis showed that the incidence of liver disease in patients with endocrine and metabolic diseases was positively correlated with the level of liver function (P＜0.05), but not with the incidence of abnormal liver function (P＞0.05).Conclusion Liver disease has a certain relationship with endocrine metabolism, which can coexist with liver disease. Liver disease will increase liver function damage. Clinical treatment of endocrine and metabolic diseases should be supplemented by liver protection treatment, so that patients can gradually return to normal liver function with the improvement of the disease, and further improve the prognosis.

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更新日期/Last Update: 1900-01-01